Unele aspecte epigenetice ale disfuncțiilor spermatogenezei

Abstract

Contemporary society faces a relatively high frequency of spermatogenesis dysfunctions. The factors that cause these dysfunctions can affect the structure of DNA, as well as lead to various epigenetic changes. The main epigenetic mechanisms of gene function regulation are DNA methylation, histone changes, and chromatin remodeling. Currently, research on sperm epigenome has a a direction of perspective.