Abstract:
Aim: Evaluation of the etiology of the bronchial exudate by bacteriological examination in
children with chronic bronchopulmonary diseases complicated by Aspergillus fumigatus infection.
Material and methods: In the retrospective clinical study, Aspergillus fumigatus co-infections
with bacterial infections were evaluated in 53 children with chronic bronchopulmonary diseases. The
bacteriological analysis was performed by examining the bronchial exudate. The infection with
Aspergillus fumigatus was evaluated serologically (indirect hemaglutination), immunoenzymatic
antigen. Statistically analyzed materials: Microsoft Excel, Epi Info –3.5.
Results: The children in the study were distributed according to the nosological entity, such as
with cystic fibrosis (CF) – 27 children (50,9%) and chronic bronchopulmonary diseases – 26 children
(49,1%). In the children from the bacteriological study, infections were indentified with: unspecified
gram negative germs (BNGN) were identified - 2 children (2,3%); Klebsiella pneumoniae – 5 children
(5,8%); Ps.aeruginosa- 16 children (18,6%); Neisseria spp - 2 children (2,3%); Staphylococcus aureus
– 20 children (23,3%); Streptococcus mitis/oralis – 1 child (1,2%); Streptococcus viridans – 9 children
(10,5%), Titer of infection with Aspergillus fumigatus in the serum (IgM, IgA, IgG) of 21 children
from the study equal to 1/803,8±17,3.
Conclusions: Children with chronic bronchopulmonary diseases, Aspergillus fumigatus
infection colonizes more frequently with Ps.aeruginosa (18,6%); Staphylococcus aureus (23,3%);
Streptococcus viridans (10,5%).
