1. COLECȚIA INSTITUȚIONALĂ: Recent submissions

  • Tumor-infiltrating CD79α positive lymphocytes in breast cancer 
    Portnoi, Elena; Brînza, Dumitru; Foca, Ecaterina; Adam, Consuela; Pînzaru, Valeria; Stratan, Valentina; Fulga, Veaceslav (CEP Medicina, 2026)
    Introduction. Tumor-infiltrating lymphocytes (TILs) represent a critical component of the immune microenvironment in breast cancer, influencing tumor progression and patient prognosis. Among Bcell markers, CD79α is a ...
  • PAX5 expression in breast carcinoma 
    Portnoi, Elena; Brînza, Dumitru; Foca, Ecaterina; Adam, Consuela; Pînzaru, Valeria; Stratan, Valentina; Fulga, Veaceslav (CEP Medicina, 2026)
    Introduction. PAX5 is a transcription factor essential for B-cell lineage differentiation, but recent studies suggest its involvement in other types of neoplasms, including breast carcinoma. Understanding PAX5 expression ...
  • Medication non-adherence in chronic conditions 
    Caracaș, Anastasia; Latus, Svetlana; Bacinschi, Nicolae (CEP Medicina, 2026)
    Introduction: Medication adherence in chronic diseases is conceptualized as a multidimensional, longitudinal construct encompassing initiation, implementation, and discontinuation of therapy. Failure to initiate prescribed ...
  • Kinking sydrome of the abdominal aorta: case presentation 
    Botnari, Tatiana; Zorina, Zinovia; Babuci, Angela; Cealan, Andrei; Catereniuc, Ilia; Botnaru, Doina; Ostahi, Nadia (CEP Medicina, 2026)
    Introduction: Abdominal aortic kinking syndrome is a rare congenital malformation characterized by angulation of the abdominal aorta (AA), which, depending on the degree of inflection, can alter the origin and trajectory ...
  • The role of angiogenesis in osteoarthritis 
    Basistii, Alexander; Pulucciu, Elena; Grusac, Evgheni; Bețisor, Alexandru; Cepoi, Daniela; Sardari, Veronica (CEP Medicina, 2026)
    Background. Osteoarthritis (OA), a degenerative joint disease, involves synovial inflammation, subchondral bone erosion, and cartilage degeneration affecting nowadays more than 630M people worldwide for which there is ...
  • Correlation between the width of the facial nerve trunk and greater auricular nerve 
    Babuci, Angela; Midrigan, Corina; Zorina, Zinovia; Bendelic, Anastasia; Ostahi, Nadia; Botnari, Tatiana; Botnaru, Doina; Lehtman, Sofia; Motelică, Gabriela; Nastas, Liliana (CEP Medicina, 2026)
    Introduction. Surgical repair of the facial nerve trunk (FNT) after iatrogenic injures, trauma or tumor removal is one of the primary goals in head and neck surgery. As grafts for facial nerve repair in large nerve defects ...
  • Brainstem in morphoclinical aspect 
    Armașula, Mihaela; Zorina, Zinovia (CEP Medicina, 2026)
    Introduction. Morphoclinical analysis of the brainstem is essential due to its structural complexity and the severity of associated disorders. Stroke represents the main acute neurological pathology, presenting a wide ...
  • Cellular therapy in diabetic retinopathy 
    Vicol, Catalina; Nacu, Viorel (CEP Medicina, 2026)
    Introduction. Diabetic retinopathy is one of the most common microvascular complications of type 1 and type 2 diabetes and a major cause of visual impairment and blindness in adults. Its pathogenesis involves complex ...
  • Complex reconstruction of the postoperative cavity in type B1 tympanic paraganglioma using autologous tissues 
    Ursachi, Anastasia; Vetricean, Sergiu; Buracovschi, Nicolai; Osman, Victor; Sencu, Eusebiu (CEP Medicina, 2026)
    Introduction. Tympanic paragangliomas are rare, highly vascular tumors that can resemble chronic ear infections, which may delay diagnosis and treatment. Removing large tumors can leave wide tissue defects and carries a ...
  • ADSC - enriched autologus fat grafting in facial rejuvenation 
    Tripadus, Cristiana; Ghețiu, Alexandru; Chele, Nicolae; Sîrbu, Dumitru (CEP Medicina, 2026)
    Introduction: Autologous fat transfer (AFT) is widely applied in facial rejuvenation due to its biocompatibility and capacity to restore age-related volume loss. Although patient satisfaction remains high, long-term ...
  • Methods for inducing glaucoma in animal models: experimental approaches and research applications 
    Țarălungă, Tatiana; Scheghelskaya, Elena; Țarălungă, Maxim; Vicol, Adrian; Iacubițchi, Maria; Paduca, Ala; Bendelic, Eugeniu; Nacu, Viorel (CEP Medicina, 2026)
    Introduction. Glaucoma is a leading cause of irreversible blindness worldwide, characterized by progressive optic neuropathy and retinal ganglion cell loss, often associated with elevated intraocular pressure. Experimental ...
  • Applications of neural stem cells-literature review 
    Țarălungă, Tatiana; Scheghelskaya, Elena; Crăciun, Ion; Costru-Tașnic, Elena; Nacu, Viorel (CEP Medicina, 2026)
    Background. Neural stem cells (NSCs) are multipotent progenitor cells capable of self-renewal and differentiation into the principal cellular components of the central nervous system, including neurons, astrocytes, and ...
  • Lymphatic tissue engineering: experience of the laboratory of tissue engineering and cell culture at Nicolae Testemitanu State University of Medecine and Pharmacy 
    Aparece, Alexandra; Jian, Mariana; Cobzac, Vitalie; Nacu, Ana-Maria; Hîncota, Dumitru; Verega, Grigore; Nacu, Viorel; Stoian, Alina (CEP Medicina, 2026)
    Introduction: Lymphedema (LE) is a chronic and progressive disease caused by damage to lymphatic vessels and/or lymph nodes (LNs). Conservative treatment includes complex decongestive therapy, physiotherapy, exercise, ...
  • Impact of donor age on 10-year graft survival in deceased-donor kidney transplantation: a modern registry analysis 
    Scevenels, Laura; Bogdanov, Alan; Topor, Boris (CEP Medicina, 2026)
    Introduction: The growing shortage of donor kidneys has led to the increased utilization of older deceased donors. Age-related structural changes in the renal parenchyma may reduce graft longevity, raising clinical ...
  • Hyperglycemic modulation of human retinal pericytes: morphological responses and osmotic controls in an in vitro model of microvascular stress 
    Pavlovschi, Ecaterina; Mărițoi, Tatiana; Kurtev, Stefan; Tagadiuc, Olga (CEP Medicina, 2026)
    Introduction. Retinal pericytes play an emphasizing role in maintaining microvascular integrity and are among the earliest cells affected during diabetic microangiopathy. Robust experimental hyperglycemia models are ...
  • In vitro modulation of pseudocholinesterase activity by Cu-thiosemicarbazone compounds in rat C6 glioma cells 
    Pantea, Valeriana; Pavlovschi, Ecaterina; Sardari, Veronica; Șveț, Inna; Tagadiuc, Olga (CEP Medicina, 2026)
    Introduction. Glioma represents one of the most aggressive forms of primary tumors of the central nervous system, characterized by rapid proliferation, high invasiveness, and resistance to conventional therapies. The C6 ...
  • Antitumor potential of sanguinarine: molecular mechanisms and emerging role in targeted cancer therapy 
    Mihalciuc, Olga; Reabîșeva, Marina; Gudumac, Valentin; Andronache, Lilia (CEP Medicina, 2026)
    Intoduction. Conventional chemotherapy is often limited by primary and secondary tumor resistance, systemic toxicity, and reduced efficacy in advanced disease stages. These limitations have increased interest in natural ...
  • The immediate and delayed loading of dental implants 
    Melnic, Svetlana; Uncuța, Diana; Poștaru, Cristina (CEP Medicina, 2026)
    Introduction: Implant supported restorations for partially edentulous patients are a well-accepted and predictable treatment modality. Provisional restorations may be used at the time of implant placement or after an ...
  • Evaluation of BCL-2 expression in 33 consecutive cases of serous ovarian carcinoma 
    Mărițoi, Tatiana; Pînzaru, Valeria; Tașci, Xenia; Fulga, Veaceslav; Șaptefrati, Lilian; David, Valeriu (CEP Medicina, 2026)
    Introduction: Serous ovarian carcinoma, the most frequent subtype, exhibits aggressive behavior and late diagnosis. The BCL-2 protein, with its anti-apoptotic role, promotes tumor cell survival. BCL-2 expression is ...
  • Spectral analysis of the submandibular gland sialoliths 
    Lehtman, Sofia; Babuci, Angela; Motelica, Gabriela; Zorina, Zinovia; Dandara, Mihaela; Procopenco, Olga (CEP Medicina, 2026)
    Introduction. Sialoliths are intraductal or intraparenchymal calculi of the large salivary glands. They consist of organic and inorganic mater, with a nucleus and plastic peripheral structures. The sialoliths predominantly ...

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