1. COLECȚIA INSTITUȚIONALĂ: Recent submissions

  • Epithelial tissue as a component of the immune system 
    Pila, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Epithelial tissue is an essential component of the human body, not only for its basic functions such as protection, secretion and absorption, but also for its significant contribution to the immune system. ...
  • The role of virtual and augmented reality in neuroscience 
    Saranciuc, Ruslana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Virtual (VR) and augmented reality(AR) are new tools that are already being successfully used in neurorehabilitation and therapy. But these technologies are still perceived by some experts with skepticism. ...
  • Gluten intolerance. Celiac disease 
    Volc, Renata (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Celiac disease (CD) is an immune-mediated inflammatory condition of the small intestine that occurs in genetically predisposed individuals when they are exposed to gluten (a plant-based protein component found ...
  • The influence of type 2 pregestational diabetes mellitus on the fetus 
    Surlaru, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of type 2 diabetes among women of reproductive age is increasing. According to the latest data from the International Diabetes Federation in 2019, one in six live births is affected by hyperglycemia ...
  • A case study of cardiovascular disorders and its consequences in a patient with diabetes mellitus type 2 with metabolic dyslipidemia 
    Joseph, Daniel (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The major aim of this case study is to analyse and understand the complicated relationship between cardiovascular disease, in a patient diagnosed with diabetes mellitus type 2 with a mixed complication stage ...
  • The role of gut microbiota metabolites in atherosclerosis 
    Berliba, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Changes in gut microbiota metabolites(GMM) is linked to the development of CVD, which includes atherosclerosis, hypertension, ...
  • Mechanisms of action and metabolic effects of anticoagulants 
    Curelariu, Mădălina; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Anticoagulant drugs antagonize coagulation and are used to prevent or prolong the clotting time. Nowadays physicians from different fields possess a broad panel of multiple anticoagulants to meet a patient's ...
  • A case of suspected lipodystrophy in an insulinresistant patient 
    Tishya, Mukherjee (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Lipodystrophy syndrome, a rare disease associated with leptin deficiency and characterized by disproportionate fat loss, is linked to me tabolic disorders like dyslipidemia and severe insulin resistance. It ...
  • Decoding AMD: exploring lipofuscin accumulation and metabolomics insights 
    Platon, Angela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Age-related macular degeneration (AMD) represents a multifactorial, degenerative pathology of the retina, with mechanisms that remain incompletely understood. Lipofuscin accumulation is believed to play a ...
  • Neurosyphilis case report 
    Rotari, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Neurosyphilis is relatively rare in last decades, due to the epidemiological measures in force. Because of the variety of clinical manifestations, from mild behavioral disturbances to paralysis and death, ...
  • Estrogen therapy - metabolic and clinical consequences 
    Briciuc, Eugenia; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Estrogen therapy has been a cornerstone in the treatment of various medical conditions, especially in menopausal management symptoms, preventing osteoporosis and addressing gynecological concerns. However, ...
  • Interplay of glucose metabolism and its influence on myopia development 
    Dacu, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Available data suggests that by the year 2050, approximately half of the global population will experience nearsightedness, marking myopia as a genuine worldwide epidemic. To this day, the impact of nutrition ...
  • Unlocking the shield: examining retinal protection via macular carotenoids' antioxidant capacity 
    Buraga, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The human retina, crucial for vision, is highly susceptible to oxidative damage due to its exposure to light and high metabolic activity. Three macular xanthophylls (MXs) – zeaxanthin (Z), lutein (L), and ...
  • The biochemical relationship between stress and autoimmunity 
    Buciumaș, Aurelia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Stress is a state of concern or psychological tension which appears because of a difficult situation. Stress is a normal response of our body that helps us survive all the challenges and threats of our ...
  • Molecular aspects of aminoglycoside ototoxicity 
    Cojevnicov, Emanuela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Aminoglycosides are a class of antibiotics widely used in pediatric clinical practice due to their effectiveness against gram-negative bacterial infections. Despite this, they are known to have cochleotoxicity ...
  • Acute viral infection as a trigger for DSNMG: a case report 
    Stafi, Vlada; Stavila, Iulia; Tofan, Lucian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Categorical evidence shows that patients with Acute Respiratory Viral Infections have a higher risk of concurrently developing autoimmune diseases, reflecting phenotypic heterogeneity in MG. The association ...
  • Transcutaneous auricular vagus nerve stimulation efficacy in drug resistant epilepsy treatment 
    Iurcu, Victoria; Olaru, Natalia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Transcutaneous auricular vagus stimulation (taVNS) modulates the locus coeruleus-norepinephrine (LC-NE) network through impulses delivered to the external ear via Aβ fibers using frequencies mostly between ...
  • Methods of term labor induction for women with a previous caesarean section 
    Curlat, Vlad (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The term pertains to diverse methodologies employed for the initiation of parturition in gravid individuals who have previously had a cesarean section(c-sec) and have reached the full term gestational period. ...
  • Ovarian function in women of reproductive age after hysterectomy 
    Vataman, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. As a core reproductive organ, the ovary has two distinct functions, producing mature oocytes for fertilization and secreting sex hormones to sustain the normal activities of multiple organs. Aim of study. ...
  • The clinical and immunological features of myasthenia gravis with anti-musk antibodies 
    Țîrdea, Alexei (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Myasthenia gravis is an autoimmune disorder of the neuromuscular junction, caused by autoantibodies synthesized against AChR, MuSK or LRP4. There is also a seronegative form, where antibodies are not detected. ...

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