1. COLECȚIA INSTITUȚIONALĂ: Recent submissions

  • Erectile dysfunction in patients with periodontal disease 
    Gamureac, Oxana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Erectile dysfunction (ED) is the inability to achieve or maintain an erection for a sufficient duration for sexual intercourse. Periodontal disease is primarily the result of infection and inflammation of the ...
  • From oxidative stress to bone healing: a biochemical insight into the fracture recovery process 
    Dănilă, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Within bone tissue, osteoclasts release oxidative stress (OS) compounds, vital for calcified tissue breakdown and bone healing after fractures. However, imbalances between oxidant compounds like reactive ...
  • Bioethical aspects of the rehabilitation of patients with type 2 diabetes in conditions of anti-pandemic restrictions 
    Croitoru, Vera (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rehabilitation is essential for many health conditions such as acute stroke, cardiac events and endocrine diseases and others. It is estimated that due to the SARS COV-2 pandemic, an estimated range of 1.3–2.2 ...
  • The involvement of micro-RNAs in cardiovascular pathologies 
    Bairamculov, Azamat (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Micro-RNAs are short molecules of ribonucleic acid with significant regulatory functions in controlling gene expression within eukaryotic cells. These small molecules play a crucial role in post-transcriptional ...
  • Nonalcoholic fatty liver disease pathogenic mechanisms and non-invasive diagnosis 
    Uncu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-alcoholic fatty liver disease (NAFLD) affects a quarter of the world's population and is one of the most common liver diseases. It can progress to liver cirrhosis and hepatocellular carcinoma (HCC). ...
  • Clinical characteristic of adults hospitalized with COVID-19 in the Republic of Moldova 
    Ciobanu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The global impact of the unprecedented COVID-19 pandemic has prompted an urgent need to comprehensively understand the clinical characteristics of affected individuals for effective healthcare management. ...
  • The role of JAK-inhibitors in the treatment of rheumatoid arthritis 
    Cozma, Octavian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis is a systemic chronic autoimmune inflammatory disease characterized by persistent destructive synovitis with extra-articular manifestations. Despite the recent development and recommended ...
  • Genetic aspects of thrombophilia in pregnancy 
    Antoci, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Thrombophilia represents a condition that increases blood coagulability and the risk of clots. Physiological changes during pregnancy, such as excess fibrinogen synthesis and increased concentration of ...
  • Hormonal disturbances in the polycystic ovary syndrome 
    Colin, Mihai; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Polycystic ovary syndrome (PCOS) is an endocrine pathology that affects women of reproductive age. Hormonal disturbances in the PCOS are the central cause of heterogenous clinical presentation involving ...
  • Obesity: particular complications in pregnant women 
    Sofonov, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity is a nosological entity determined by the body's psychosomatic imbalance, resulting in energy excess and pathological expansion of adipose tissue causing severe complications and increased overall ...
  • Vitamin D metabolism in hepatorenal syndrome 
    Harees, Noushad Juguma (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hepatorenal syndrome (HRS) is a consequence of liver cirrhosis, which is the final stage of chronic liver disease with irreversible damage and the existence of regenerating nodules. Renal function is disturbed ...
  • Medical and social patterns of pelvic inflammatory disease in the Republic of Moldova 
    Căldare, Arina; Grăjdean, Victor; Vicol, Adrian; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pelvic inflammatory disease (PID) represents a significant medical and social problem. It encompasses conditions such as endometritis, salpingitis, hydrosalpinx, pyosalpinx, and tubo-ovarian abscess. The ...
  • Application of virtual reality (VR) in the planning and simulation of urgent neurosurgical interventions 
    Todica, Vladislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Emergency neurosurgery is required for acute cerebrovascular disorders, intracranial and spinal cord traumas, and pre-cerebral artery occlusion/stenosis. It requires immediate and accurate management. Virtual ...
  • Chorio-villous mesenchymal stromal dysplasia in the course of pregnancies 
    Grosu, Eugenia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Mesenchymal stromal dysplasia is a developmental anomaly of the placenta that is characterized microscopically by dilated stem villi with a myxoid or hydropic appearance, cisterna lacunae, and lack of ...
  • Case report of a perforated intrauterine device into sigmoid colon 
    Prepeliță, Mădălina; Lavric, Irina; Găină, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intrauterine devices (IUD) have become one of the most popular birth control methods worldwide. Uterine perforation is an uncommon complication of IUD, with an incidence 1: 1,000 insertions. Perforation may ...
  • The impact of the 3 endothelium derived gasses (H2S, No, Co) on vascular endothelium homeostasis 
    Leca, Magdalena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Vascular endothelial fulfills a lot of functions having a decisive role in the control of circulatory and general homeostasis. Among the endothelium derived factors three gasses occupy a special position being ...
  • The pathophysiology of iron deficiency in the body, endangerment of the absorption, transport and storage of the cation. The main mechanisms 
    Gumeniuc, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Iron plays an important role in a multitude of physiological processes, such as the transport of oxygen from the lungs to the tissues, the release of molecular oxygen from organic compounds, favors the exchange ...
  • The role of genetic aspects in pathophysiology of cushing syndrome 
    Pascari, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cushing's syndrome is considered a rare disease with an incidence of 0.2– 0.5 million population per year, with an average age of 41 years at diagnosis and 1–2 cases per 100,000 population per year. As known, ...
  • Iron metabolism aspects: malabsorption, transport and storage related diseases 
    Rimbu, Damiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Iron Deficiency Anemia (IDA), the main Iron deficiency-based disorder, is one of the leading global health problems, affecting 22,8% (2019) of the population, the most exposed groups being rapidly growing ...
  • The morphopathological aspect of metabolicassociated fatty liver disease 
    Trocin, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Being proposed in 2020, the novel terminology for Metabolic-Associated Fatty Liver Disease (MAFLD) involves the strong association of fatty liver disease with metabolic factors rather than NAFLD, the term ...

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