Rolul factorilor epigenetici în procesul de derulare a spermatogenezei

Abstract

The special properties of spermatozoa are established by the processes of spermatogenesis and maturation simultaneously with their epigenome. It is known that there is a close correlation between environmental factors and the outcome of their action on the phenotype, which is particularly significant for spermatogenesis, reproduction and development. Environmental epigenetic effects on sperm genesis and maturation influence male reproductive health and the epigenetic inheritance of offspring. The effect of environmental factors in epigenetics and its reversibility can present intragenerational adaptive implications, with the subsequent transmission to the next generations through the semen of the acquired traits, and the adaptive responses will favor long-term natural selection, changing their frequency in the population.