Abstract:
Background.There are many applications of the amniotic membrane in regenerative medicine, it
serves as a source of stem cells and potent growth factors and like a very biocompatible natural
scaffold; also the amniotic membrane serves as an efficacious nanorecipient for medicines delivery,
due to its raised entrapment properties.
Materials and methods. Was performed a controlled clinical study, which were involved 10 patients,
who suffered from neuropathic foot ulcers, and treated by amniotic membrane transplant. The age of
patients was between 18-70 years and suffered from ulceration below the ankle for a month or more.
Results. The main result of this study was to assess the proportion of ulcers, that full closure in 9 weeks
in treated with amniotic membrane. Thus, 78% of all patients obtained full closure.
Conclusion. The clinical application of amniotic membranes maintains the anatomical and structural
configuraAmniotic membrane transplantation is a common practice in regenerative medicine due to
its potential to provide stem cells and potent growth factors. It is also a biocompatible natural scaffold
that can be used as an effective nanorecipient for delivering medicine.
