Abstract:
Background. The progressive evolutionary forms of liver cirrhosis are especially characterized by the
damage to the hepatic arterial.circuit. Although the blood flow through the hepatic artery is much lower
than through the portal vein, the arterial blood provides the liver with more than 50% of the oxygen
required. The hepatic artery constitutes the nutritional vasculature, reprezenting a branch of the celiac
trunk that brings blood enriched with O2 to the liver. The quadrate lobe is vascularized by the middle
branch of the hepatic artery, and the caudate lobe by the right and left brances of the hepatic artery.
The arteriolar sphincters are positioned anterior to the passage of arterial blood in the sinusoids.
Material and method. A study was conducted, including 32 patients with liver cirrhossis – 22 men
and 12 women, average age - 48±0,37 years. The calculated linear parameters in the hepatic artery by
Doppler quantification.
Result. The arterial circuit in 65% of patients included the dilation of the diameter of the hepatic artery,
which was associated with a decrease in diastolic velocity (38%) and an increase in the volume velocity
of blood flow in the studied segment (57%). A linear increase in blood flow by approximately 70%
was revealed. The volume of blood flow speed in the hepatic artery was 269±115 ml/min. As the
pathology progressed, the flow volume also increased: from 785±0.5 ml/min to -979±138 ml/min.
Conclusions. 1.The change in blood flow in the hepatic artery represents an informative hemodynamic
parameter, which subsequently invokes the process of severe liver damage. 2.In these patients, the
reduction of the elasticity and tone of the large arteries, the decrease in the filling of the small and
medium caliber arteries of the liver with the modification of the gradient of the arterial circuit during
systole was highlighted.
