Abstract:
Transplant medicine in the Republic of Moldova involves numerous psychological challenges for patients,
involving significant risks of depression, anxiety and post-traumatic stress, which influence psychosocial
adaptation and therapeutic outcomes with the need for specialized psychological support. The study purpose is
to evaluate psychological problems in transplant patients from the Republic of Moldova and determine their
impact on therapeutic adherence and post-operation quality of life. The analysis is based on the specialized
literature of mental health and on the available information on patients who have benefited from kidney and
liver transplantation in the Republic of Moldova. The parameters included the prevalence of depression,
anxiety and cognitive disorders. The analysis was performed using descriptive statistics. A detailed review of
the literature revealed that depression is a significant challenge, manifested by loss of interest in daily activities
and feelings of worthlessness. The anxiety is manifested by persistent fear of rejections of the transplanted
organ and excessive concerns about health. Cognitive disorders, such as difficulty concentrating, impaired
memory, and periodic confusion, have been identified as factors that compromise the appropriate management
of postoperative treatment. All of these psychological problems negatively influence therapeutic adherence,
social integration, and overall quality of life. The hypothesis regarding the negative influence of psychological
disorders on transplant outcomes and treatment adherence was validated. It is imperative to integrate
organized psychological support into current medical practice for transplant patients in the Republic of
Moldova.
