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| dc.contributor.author | Tagadiuc, Olga | |
| dc.contributor.author | Gudumac, Valentin | |
| dc.contributor.author | Andronache, Lilia | |
| dc.contributor.author | Rîvneac, Elena | |
| dc.date.accessioned | 2019-06-25T11:34:57Z | |
| dc.date.available | 2019-06-25T11:34:57Z | |
| dc.date.issued | 2010 | |
| dc.identifier.citation | TAGADIUC, O., GUDUMAC, V., ANDRONACHE, L., RÎVNEAC, E. Sinfluenţa compuşilor coordinativi ai cuprului asupra activităţii proteazelor lizozomale hepatice. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 11-a. Chișinău: CEP Medicina, 2010, vol. 1: Probleme medico-biologice si farmaceutice, pp. 266-270. ISSN 1857-1719, | en_US |
| dc.identifier.isbn | 978-9975-113-45-8 | |
| dc.identifier.issn | 1857-1719 | |
| dc.identifier.uri | http://repository.usmf.md/handle/20.500.12710/3972 | |
| dc.description | Laborator biochimie USMF “N.Testemiţanu” | en_US |
| dc.description.abstract | The aim of the study was to investigate the influence of copper coordinative compounds CMT-28 and CMT-67 and their combinations with the cyanobacterial bioremedy BioR on the activity of lysosomal proteases in the liver of intact rats. It was established that all studied substances enhance the activity of cathepsines D, G, L, H, B and leucineaminopeptidase. CMT-67 and BioR show synergism in the modulation of the lysosomal proteases in the liver of intact animals, causing overlapping of the effects of these remedies. | en_US |
| dc.description.abstract | Studiul a avut scopul de a cerceta influenţa compuşilor coordinativi ai cuprului CMT-28 şi CMT-67 şi a combinaţiilor lor cu remediul de origine cianobacterială BioR asupra activităţii proteazelor lizozomale în ficatul animalelor intacte. S-a stabilit că toate substanţele studiate amplifică activitatea catepsinelor D, G, L, H, B şi a leucinaminopeptidazei. CMT-67 şi BioR manifestă sinergism în modularea activităţii proteazelor lizozomale hepatice la animalele sănătoase, administrarea lor concomitentă determinînd cumularea efectelor acestor remedii. | ro |
| dc.language.iso | ro | en_US |
| dc.publisher | CEP Medicina | en_US |
| dc.title | Sinfluenţa compuşilor coordinativi ai cuprului asupra activităţii proteazelor lizozomale hepatice | en_US |
| dc.title.alternative | Influence of the coordinative copper compounds on the activity of liver lisosomal proteases | en_US |
| dc.type | Article | en_US |
