Based on a study of selective sciens was characterized the farmacokinetics of metoclopramide monohydrochloride, the interaction between metoclopramide and Cytocrome P450, the ability of the substance to inhibit drug – ...
We used Diclofenac and phisico-chemical methods in the pure substance for its analysis in the blood plasma. The identification ofMarquis and Liebermann reaction. Chromatography on the thin layer in the ethylacetate-metanol-ammonia ...
Calypso® 480 SC (active ingredient of tiacloprid) is the chloronicotinil insecticide. It is a product with systematic high activity in the plant, acting on the vermin insects by contact or indigestion. The tiacloprid has ...
Was elaborated and studied 10 formulations orally disintegrating tablets with spironolactone, to increase the pharmaceutical availability and was calculated the time of dissolution of 50% of substance. The solid dispersion ...
The main pharmacokinetic parameters and molecular structure data of captopril were highlighted. On the basis of this parameters of molecular structural data correspondency to Lipinski's rule or "rule of five” were established. ...
Some bibliographical facts about life elements, their topography in human organism, importance for vital activity, periodicity of quantitative content in life substance was generalized.
S-au generalizat unele ...
The project of innovation and technological transfer “Implementation of Floralghin, ointment and dental adhesive paste in medical practice” N 09.824.09.101T intends to elaborate and place into medical use two new domestic ...
The aims of research were to develop a new spectrophotometric Azithromycin assay in pure substance and in capsules, which would be corresponding to all requirements assigned to the instrumental methods of analysis. There ...
It was elaborated a pharmaceutical form for external use – the combined ointment with Izohidrafural and Metiluracil and also it was elaborated the method of extraction of active principles from it. The medicine combines ...
It was researched the physical, chemical compatibility of izohidrafural with metiluracil to be able to combine them in the same pharmaceutical form - ointment. It will have a complex action: antibacterial due to izohidrafural ...
Emergency contraception is an „after sex” method of preventing pregnancy after unprotected intercourse or failed contraception. Most common method of emergency contraception is a special contraceptive pill Escapelle with ...
In toxic liver diseases along with characteristic parametres changes (AST, ALT, necrotic substances etc.) there are some metabolic disturbances (moderate hypoglicemice and hypocreatininemie, hypouricemie), wich can be used ...
In experiments on white rats was established that enterosorbtion with carbo activatus and Medicas E does not prevent the reduction of lipid peroxidation products indices activity in the myocardium after 7 and 14 days in ...
In the last years in Republic of Moldova is observed an inceasing incidence of thyroide pathologies manifested through hypothyroidism, hyperthyroidism, autoimune processes, cysts and thyroid cancer. Along with the improvement ...
Studies in vitro demonstrate that benzil-alcoholic solution of juglone poses a pronounced antibacterial activity against gram-positive (Staphilococcus aureus (Wood-209), Streptococcus faecalis)and gram-negative (Escherichia ...
The sensibility results analysis of pathogenic agents to the antibacterial remedies demonstrated an increseang of the microbial rezistance incidence to the important group of antibiotics and chemotherapeutics. Intrahospital ...
In the experiments on rats the aspects of the isothioureic derivatives interaction with hyperbaric oxygen (HBO) on the lipid metabolism level was studied. HBO (6 ata 50 min) caused the increase of plasmatic concentration ...
We decided to obtain new bioactive substances by inserting the radicals of thyoureea to the N4 atom of Davosine, a sulphamide with important therapeutic properties. We have treated this sulphamide with various aromatics ...
It was studied a new drug of entomologic origin – imupurin, obtained from Lepidoptera pupae, as a monotherapy for AIDS infected patient. The usage of this drug during 9 months leads to descrease of viral load (from 35 400 ...
This review focuses on biological agents in the treatment of rheumatoid arthritis, chronic inflammatory disease that attacks the synovium of joints, which affects about 1% of the world's population. There are various ...