Evaluarea modificărilor cardiovasculare la copii cu astm bronşic sever în funcţie de tratament

Abstract

Bronchial asthma (BA) is one from most frequent chronic obstructive bronchopulmonary diseases in children. Conformable to ISAAC data (International Study of Asthma and Allergy in Children), BA affects 5-20% of children on earth. The programs of actual treatment depend from evolutionary forms and complications. The persistent severe forms need administration of combined therapy, including drugs with secondary effects on cardiovascular system. Our retrospective study aimed the analysis of cardiovascular modifications in 240 children with BA. In children with severe BA (142 (51,9%) children from total 240) arrhythmias and other modifications of repolarization processes were present in over 80% of patients, including 3 children which had signs of cor pulmonale, independent from age.

Astmul bronşic (AB) este una din cele mai frecvente maladii cronice bronho-pulmonare obstructive la copii. Conform datelor ISAAC (Studiul Internaţional al astmului şi alergiei la copii), AB afectează 5-20% din copiii de pe globul pământesc. Programele de tratament actual depind de formele evolutive şi complicatii. Formele severe persistente necesită administrarea terapiei combinate, inclusiv de medicamente cu efecte secundare asupra sistemului cardiovascuar. La copii cu AB sever (142 (51,9%) copii din 240 pacienţi total) aritmii şi alte modificări ale proceselor de repolarizare au fost prezente în peste 80% dintre pacienţi, inclusiv 3 copii care au avut semne de cord pulmonar, independent de vârstă.