dc.contributor.author |
Corciovă, Andreia |
|
dc.contributor.author |
Ciobanu, Constantin |
|
dc.date.accessioned |
2019-11-22T10:45:26Z |
|
dc.date.available |
2019-11-22T10:45:26Z |
|
dc.date.issued |
2014 |
|
dc.identifier.citation |
CORCIOVĂ, Andreia, CIOBANU, Constantin. Determinarea spectrofotometrică a codeinei din comprimate. In: Sănătate Publică, Economie şi Management în Medicină. 2014, nr. 6(57), pp. 31-33. ISSN 1729-8687. |
en_US |
dc.identifier.issn |
1729-8687 |
|
dc.identifier.uri |
http://repository.usmf.md/handle/20.500.12710/7147 |
|
dc.identifier.uri |
http://revistaspemm.md/wp-content/uploads/2019/05/cm6_57_2014.pdf |
|
dc.description |
Universitatea de Medicină şi Farmacie Grigore T. Popa,
Iaşi, România,
Facultatea de Farmacie,
Disciplina Analiza Medicamentului, Conferința științifico-practică cu participare internațională Centrul de Sănătate Publică din municipiul Chișinău – 70 de ani la straja sănătăţii 23 octombrie 2014 |
en_US |
dc.description.abstract |
A spectrophotometric method for the determination of codeine phosphate in tablet dosage forms has been described, based on the codeine ability to form with bromphenol blue in acidic media, a complex extractible in chloroform. The absorbance of the formed ion-pair complex was monitored spectrophotometrically at 413 nm. The range of linearity for the obtained complex was found to be 0.1–0.5 mg/ml. The proposed method has been successfully applied for the determination of codeine in industrial pharmaceutical forms |
en_US |
dc.description.abstract |
В данной статье представлен один из методов спектрофотометрического определения кодеина фосфата в таблетках, который основан на способности образовывать с бромфеноловым синем в кислой среде комплексное соединение, извлекаемое в хлороформе. Оптическую плотность образованного комплекса измеряли при длине волны 413 нм. Аналитический ответ был линейным в интервале концентраций 0,1 – 0,5 мг/ мл. Предлагаемый способ был успешно применен для определения фосфата кодеина в фармацевтических препаратах, производимых промышленным способом. |
|
dc.language.iso |
ro |
en_US |
dc.publisher |
Asociația Obștească ”Economie, Management și Psihologie în Medicină” din Republica Moldova |
en_US |
dc.subject |
codeine phosphate |
en_US |
dc.subject |
bromphenol blue |
en_US |
dc.subject |
ion-pair complex |
en_US |
dc.subject.mesh |
Codeine--analysis |
en_US |
dc.subject.mesh |
Codeine--pharmacology |
en_US |
dc.subject.mesh |
Codeine--chemistry |
en_US |
dc.subject.mesh |
Bromphenol Blue--analysis |
en_US |
dc.subject.mesh |
Pharmaceutical Preparations--chemistry |
en_US |
dc.subject.mesh |
Drug Dosage Calculations |
en_US |
dc.title |
Determinarea spectrofotometrică a codeinei din comprimate |
en_US |
dc.title.alternative |
Spectrophotometric determination of codeine in tablet dosage |
en_US |
dc.title.alternative |
Спектрофотометрическое определение кодеина в таблетках |
en_US |
dc.type |
Article |
en_US |