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Determinarea spectrofotometrică a codeinei din comprimate

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dc.contributor.author Corciovă, Andreia
dc.contributor.author Ciobanu, Constantin
dc.date.accessioned 2019-11-22T10:45:26Z
dc.date.available 2019-11-22T10:45:26Z
dc.date.issued 2014
dc.identifier.citation CORCIOVĂ, Andreia, CIOBANU, Constantin. Determinarea spectrofotometrică a codeinei din comprimate. In: Sănătate Publică, Economie şi Management în Medicină. 2014, nr. 6(57), pp. 31-33. ISSN 1729-8687. en_US
dc.identifier.issn 1729-8687
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/7147
dc.identifier.uri http://revistaspemm.md/wp-content/uploads/2019/05/cm6_57_2014.pdf
dc.description Universitatea de Medicină şi Farmacie Grigore T. Popa, Iaşi, România, Facultatea de Farmacie, Disciplina Analiza Medicamentului, Conferința științifico-practică cu participare internațională Centrul de Sănătate Publică din municipiul Chișinău – 70 de ani la straja sănătăţii 23 octombrie 2014 en_US
dc.description.abstract A spectrophotometric method for the determination of codeine phosphate in tablet dosage forms has been described, based on the codeine ability to form with bromphenol blue in acidic media, a complex extractible in chloroform. The absorbance of the formed ion-pair complex was monitored spectrophotometrically at 413 nm. The range of linearity for the obtained complex was found to be 0.1–0.5 mg/ml. The proposed method has been successfully applied for the determination of codeine in industrial pharmaceutical forms en_US
dc.description.abstract В данной статье представлен один из методов спектрофотометрического определения кодеина фосфата в таблетках, который основан на способности образовывать с бромфеноловым синем в кислой среде комплексное соединение, извлекаемое в хлороформе. Оптическую плотность образованного комплекса измеряли при длине волны 413 нм. Аналитический ответ был линейным в интервале концентраций 0,1 – 0,5 мг/ мл. Предлагаемый способ был успешно применен для определения фосфата кодеина в фармацевтических препаратах, производимых промышленным способом.
dc.language.iso ro en_US
dc.publisher Asociația Obștească ”Economie, Management și Psihologie în Medicină” din Republica Moldova en_US
dc.subject codeine phosphate en_US
dc.subject bromphenol blue en_US
dc.subject ion-pair complex en_US
dc.subject.mesh Codeine--analysis en_US
dc.subject.mesh Codeine--pharmacology en_US
dc.subject.mesh Codeine--chemistry en_US
dc.subject.mesh Bromphenol Blue--analysis en_US
dc.subject.mesh Pharmaceutical Preparations--chemistry en_US
dc.subject.mesh Drug Dosage Calculations en_US
dc.title Determinarea spectrofotometrică a codeinei din comprimate en_US
dc.title.alternative Spectrophotometric determination of codeine in tablet dosage en_US
dc.title.alternative Спектрофотометрическое определение кодеина в таблетках en_US
dc.type Article en_US


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