Abstract:
Introduction. Psoriatic arthritis (APs) is a chronic seronegative inflammatory arthropathy,
associated with skin psoriasis. Sometimes it can precede the skin psoriatic lesions. Etiology and
pathogenesis remain unknown, but the genetic predisposition, the influence of the immune
system and the environment are important in the development of the disease. APs is an
invalidating disease with a different presentation in time, at one time it predominates as skin
disease, and another time as articular disease, with erosive and destructive joint changes, which
is found in about 40-60% of patients. Thus, a complex approach of the clinical features of the
disease is needed, in order to make a correct and timely diagnosis of the disease.
