Particularities in the evolution of psoriatic arthritis without skin psoriasis

Abstract

Introduction. Psoriatic arthritis (APs) is a chronic seronegative inflammatory arthropathy, associated with skin psoriasis. Sometimes it can precede the skin psoriatic lesions. Etiology and pathogenesis remain unknown, but the genetic predisposition, the influence of the immune system and the environment are important in the development of the disease. APs is an invalidating disease with a different presentation in time, at one time it predominates as skin disease, and another time as articular disease, with erosive and destructive joint changes, which is found in about 40-60% of patients. Thus, a complex approach of the clinical features of the disease is needed, in order to make a correct and timely diagnosis of the disease.