The neurogenic retroperitoneal primitive tumors

Abstract

Introduction. The histological ambiguity of the retroperitoneal space is the cause of the large specter of primitive tumors. Primitive tumors are classified in those with a mesodermal origin, neurogenic, vestigial, retroperitoneal cysts and various tumors. The neurogenic tumors may have different origins: ganglion cell (ganglioneuromas, ganglioneuroblastomas, neuroblastomas), paraganglionic system (paragangliomas, pheochromocytomas) and nerve sheath (schwannomas, neurofibromas, malignant schwannomas). The neurogenic primitives tumors usually present late symptoms or become palpable once they have reached a significant size (>10cm). The medical imaging (USG, CT, IRM) does not distinguish benign and malign tumors, and it does not reveal the histological origin. The biopsy and the histological examination of the removed tumor remain the main diagnostic methods.