Browsing The Moldovan Medical Journal 2019 by Issue Date

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  • The importance of blood cultures in the effective management of bloodstream infections 
    Burduniuc, Olga; Bunescu, Irina; Sofronie, Olga; Bivol, Maria; Craciun, Olga; Burduniuc, Aurelia; Balan, Greta (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Bloodstream infection (BSI) is a major public health concern due to its severity-related consequences. These infections pose a human health risk, as they can result in human morbidity and mortality over a short ...
  • Optimizing diagnose for visual disturbances after head trauma in school children 
    Verejan, Victoria; Bendelic, Eugeniu; Bernic, Jana (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Despite the unprecedented evolution of medical science in recent decades, trauma, especially traumatic brain injury, is one of the most common and widespread injuries worldwide. WHO reports annually over 1 ...
  • Treatment of dental subtotal coronal lesion through atraumatic surgical extrusion 
    Tapes, Adelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Clinical short crowns or teeth with insufficient height of the supragingival part are a provocation for restorative dentistry. Restoring severely damaged teeth requires a comprehensive approach, a well-planned ...
  • The key players of tumor microenvironment and their role in breast cancer 
    Carpenco, Ecaterina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cancer studies were focused mainly on tumor cells. But not that much time passed since researchers began to focus not only on neoplastic cells, but also on significant alterations in the surrounding stroma or ...
  • Features of signal transmission and aqueous media in tumorogenesis 
    Draguta, Ilarion; Mustea, Anatol; Popescu, Constantin; Iurcu, Corneliu (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: The latest studies highlight the importance of a holistic bioelectric field in the development of tumor diseases. According to some researchers, carcinogens prevent formation of a single morphogenetic field and ...
  • Janus Kinase-Signal Transducer and Activator of Transcription in target therapy of cancer 
    Shoev, Lior; Simionica, Eugeniu (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Janus kinase-signal transducer and activator of transcription (JAK-STAT) is a family of intracellular, nonreceptor tyrosine kinases that transduce cytokine-mediated signals. In the beginning of 20th century, ...
  • Specific conventional epileptic crisis 
    Cobileanschi, Oleg; Prospit, Tatiana; Dandara, Alexandru; Jelaga, Dorel (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: The brain controls how the body moves by sending small electrical signals along the nerves to the muscles. Seizures occur when abnormal signs in the brain change the way the body works. Seizures vary from person ...
  • An efficient procedure of isolation, cultivation and identification of bone marrow mesenchymal stem cells 
    Cobzac, Vitalie; Mostovei, Andrei; Jian, Mariana; Nacu, Viorel (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Bone marrow mesenchymal stem cells (MSC) have a wide application in domain of Regenerative Medicine. Of a great importance is utilization of a suitable bone marrow extraction technique that can provide a ...
  • Hepatocytes isolation from adult rats for liver recellularization 
    Jian, Mariana; Cobzac, Vitalie; Vartic, Victoria; Nacu, Viorel (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Currently hepatocytes obtaining is prerequisite to create the necessary conditions for medical research, because it is an important tool in developing of new strategies in tissue engineering domain, which ...
  • Tumor associated macrophages in breast cancer 
    Carpenco, Ecaterina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cancer research was focused on the studying of proper tumor cells for a long time. Despite the huge progress, there are still a lot of questions, that’s why new molecular markers must be identified. These could ...
  • Tuberculosis characteristics and risk factors in urban compared with rural patients 
    Tihon, Aliona; Tafuni, Ovidiu; Malik, Alina; Niguleanu, Radu; Osipov, Tatiana; Lesnic, Evelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Material and methods: A retrospective selective, descriptive study of socioeconomic, epidemiological peculiarities, case-management, diagnosis and microbiological characteristics of 694 patients with tuberculosis registered ...
  • Inoffensivity of imupurin in pregnancy 
    Pogonea, Ina; Catcov, Carolina; Ghicavîi, Victor (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Determination of imupurin inoffensivity on embryogenesis, organogenesis and teratogenesis in rats. Material and methods: The study of immupurin’s safety during pregnancy was performed on 60 rats, divided into ...
  • Informativity of perinatal medical card in fetal growth assessment 
    Bogonovschi, Eugenia; Bologan, Ion (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Failure to provide antenatal information for pregnant women as well as to complete the perinatal medical records at each visit may have negative effects on the child development. Material and methods: A ...
  • Level of cytokines in patients with pulmonary drug susceptible and resistant tuberculosis 
    Lesnic, Evelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cytokines are the regulators of the immune response in tuberculosis: TNF-alpha and CXCL8 (IL-8) are involved in the granuloma formation, IL-10 inhibits the inflammation; some chemokines increase the liver ...
  • Interests in knowledge and assistance of epilepsy 
    Cobileanschi, Oleg; Baba, Ludmila; Dandara, Alexandru; Bobea, Alexandru (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Many problems with differential treatment of epilepsy require further clarification. As far as we are concerned, we have developed therapeutic recommendations which, in our opinion, demonstrated to be effective ...
  • Topographico-anatomic peculiarities of the external carotid artery in the perinatal period 
    Slobodian, Oleksandr; Gerasym, Lalita (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: the importance of the given issue is in clarification of ontogenetic transformations of the external carotid artery during the perinatal and early neonatal periods, which is essential from the view of surgical ...
  • Aqueous humor’s biochemical composition in ocular pathologies 
    Iacubitchii, Maria; Bendelic, Eugeniu; Alsaleim, Suleiman (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Being analogous to a blood surrogate, the aqueous humor has an important role in the regulation of the homeostasis of the ocular tissues. It has many functions: provides nutrition, removes excretory products, ...
  • Treatment of inflamed skin wounds with biodegradable polymeric film “Biodep nano” 
    Popadyuk, Oleg; Kutsyk, Roman; Voloshyn, Maryana (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Experimental and clinical studies show that wound healing cannot be evaluated as optimally effective today. For the treatment of wounds today, various methods and means are used. Wound dressing was developed ...
  • Disturbance of bioelectric transmission in carcinogenesis 
    Draguta, Ilarion; Mustea, Anatolie; Popescu, Constantin; Iurcu, Cornel; Palade, Valeriu (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Despite significant financial resources invested in the field of cancer research, there has been a steady increase in the registration of new cases of malignant neoplasms. Modern technical capabilities for ...
  • Antibiotic susceptibility and some persistence factors of Gram-negative bacilli isolated from trophic ulcers 
    Balan, Greta (The Scientific Medical Association of the Republic of Moldova, 2019)
    Abstract Background: Infections that are difficult to treat might lead to high morbidity and mortality rates. In some infections, however, despite a proper antibiotic therapy, microorganisms might persist, under certain ...

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