Browsing The Moldovan Medical Journal 2019 by Issue Date

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  • An efficient procedure of isolation, cultivation and identification of bone marrow mesenchymal stem cells 
    Cobzac, Vitalie; Mostovei, Andrei; Jian, Mariana; Nacu, Viorel (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Bone marrow mesenchymal stem cells (MSC) have a wide application in domain of Regenerative Medicine. Of a great importance is utilization of a suitable bone marrow extraction technique that can provide a ...
  • Hepatocytes isolation from adult rats for liver recellularization 
    Jian, Mariana; Cobzac, Vitalie; Vartic, Victoria; Nacu, Viorel (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Currently hepatocytes obtaining is prerequisite to create the necessary conditions for medical research, because it is an important tool in developing of new strategies in tissue engineering domain, which ...
  • Types of extracranial branching of the facial nerve 
    Babuci, Angela (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Interest in anatomical variability and individual specific features of the extracranial branches of the facial nerve, taking into consideration that nowadays, people are so concerned about their physical look, ...
  • Tumor associated macrophages in breast cancer 
    Carpenco, Ecaterina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cancer research was focused on the studying of proper tumor cells for a long time. Despite the huge progress, there are still a lot of questions, that’s why new molecular markers must be identified. These could ...
  • Tuberculosis characteristics and risk factors in urban compared with rural patients 
    Tihon, Aliona; Tafuni, Ovidiu; Malik, Alina; Niguleanu, Radu; Osipov, Tatiana; Lesnic, Evelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Material and methods: A retrospective selective, descriptive study of socioeconomic, epidemiological peculiarities, case-management, diagnosis and microbiological characteristics of 694 patients with tuberculosis registered ...
  • Inoffensivity of imupurin in pregnancy 
    Pogonea, Ina; Catcov, Carolina; Ghicavîi, Victor (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Determination of imupurin inoffensivity on embryogenesis, organogenesis and teratogenesis in rats. Material and methods: The study of immupurin’s safety during pregnancy was performed on 60 rats, divided into ...
  • Informativity of perinatal medical card in fetal growth assessment 
    Bogonovschi, Eugenia; Bologan, Ion (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Failure to provide antenatal information for pregnant women as well as to complete the perinatal medical records at each visit may have negative effects on the child development. Material and methods: A ...
  • Level of cytokines in patients with pulmonary drug susceptible and resistant tuberculosis 
    Lesnic, Evelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cytokines are the regulators of the immune response in tuberculosis: TNF-alpha and CXCL8 (IL-8) are involved in the granuloma formation, IL-10 inhibits the inflammation; some chemokines increase the liver ...
  • Lambert-Eaton myasthenic syndrome – a misdiagnosed condition 
    Fala, Paula; Cojocaru, Ina; Chetrari, Larisa; Gavriliuc, Pavel; Sangheli, Marina; Lisnic, Vitalie (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Lambert-Eaton myasthenic syndrome (LEMS) is a rare disorder of the neuromuscular junction. Clinical features include proximal muscle weakness, markedly in the lower limbs, reduced deep tendon reflexes that can ...
  • Sympathetic-parasympathetic cardiac autonomic tonus during induction of anesthesia with propofol and fentanyl 
    Feghiu, Iuliana; Cobiletchi, Sergiu; Sandru, Serghei (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Administration of propofol and fentanyl for induction of general anesthesia is often associated with cardiovascular instability. This effect can be caused by changes in the cardiac autonomic tonus induced by ...
  • The role of cytomegalovirus in the development of opportunistic infections 
    Cirjau, Elena; Behta, Emilia (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: About one century ago, was found and described a new virus, which, due to its particular way of damaging cells, was called cytomegalovirus. Human is the only natural source of cytomegalovirus infection. The ...
  • Translation and validation of the Russian version of the personality inventory for DSM-5 (PID-5) 
    Lozovanu, Svetlana; Moldovanu, Ion; Vovc, Victor; Ganenco, Andrei; Blajevschi, Andrei; Beşleaga, Tudor (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: The 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) has included major and radical changes in the personality disorder (PD) diagnosis method, from categorical to dimensional ...
  • Distortion products of otoacoustic emissions and their role in assessing hearing loss in young children 
    Chiaburu-Chiosa, Doina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Hearing loss in children is far beyond the scope of otology, since audition is the basis of developing speech and cognitive abilities, as well as the child’s personality. Due to its incidence and severe ...
  • Postoperative cognitive dysfunction: physiopathological aspects and clinical evidence 
    Severin, Ghenadie (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Postoperative cognitive dysfunction (POCD) represents a decrease of cognitive abilities (memory, learning, concentration), which develops in the postoperative period after a variable amount of time (days or ...
  • Atypical pure sensory forms of chronic inflammatory demyelinating polyneuropathies 
    Gavriliuc, Eugen; Lisnic, Vitalie (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: There are still not enough data on clinical and laboratory peculiarities of atypical chronic inflammatory demyelinating polyneuropathy (CIDP), ranging from only sensitive symptoms without weakness to asymmetric ...
  • Prevalence of primary headaches in adolescents 
    Lozan, Tatiana (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: The aim of this study was to estimate overall prevalence of primary headaches and prevalence of migraine (MG) and tension-type headache (TTH) among adolescents in the Republic of Moldova. Metetial and methods: ...
  • The importance of blood cultures in the effective management of bloodstream infections 
    Burduniuc, Olga; Bunescu, Irina; Sofronie, Olga; Bivol, Maria; Craciun, Olga; Burduniuc, Aurelia; Balan, Greta (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Bloodstream infection (BSI) is a major public health concern due to its severity-related consequences. These infections pose a human health risk, as they can result in human morbidity and mortality over a short ...
  • Antibiotic susceptibility and some persistence factors of Gram-negative bacilli isolated from trophic ulcers 
    Balan, Greta (The Scientific Medical Association of the Republic of Moldova, 2019)
    Abstract Background: Infections that are difficult to treat might lead to high morbidity and mortality rates. In some infections, however, despite a proper antibiotic therapy, microorganisms might persist, under certain ...
  • Antiviral therapy in chronic hepatitis C virus infection 
    Rusu, Irina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Hepatitis C is a disease with significant global impact. According to the World Health Organization there are 71 million people chronically infected with the hepatitis C virus. About 399.000 people die each ...
  • Effect of induction of general anesthesia with propofol and fentanyl on hemodynamic response 
    Feghiu, Iuliana (The Scientific Medical Association of the Republic of Moldova, 2019)
    Abstract Background: Induction of general anesthesia with propofol and fentanyl is frequently associated with changes in arterial blood pressure and heart rate. At present, there are no clinical studies investigating the ...

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