Browsing The Moldovan Medical Journal 2019 by Issue Date

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  • An efficient procedure of isolation, cultivation and identification of bone marrow mesenchymal stem cells 
    Cobzac, Vitalie; Mostovei, Andrei; Jian, Mariana; Nacu, Viorel (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Bone marrow mesenchymal stem cells (MSC) have a wide application in domain of Regenerative Medicine. Of a great importance is utilization of a suitable bone marrow extraction technique that can provide a ...
  • Hepatocytes isolation from adult rats for liver recellularization 
    Jian, Mariana; Cobzac, Vitalie; Vartic, Victoria; Nacu, Viorel (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Currently hepatocytes obtaining is prerequisite to create the necessary conditions for medical research, because it is an important tool in developing of new strategies in tissue engineering domain, which ...
  • Tumor associated macrophages in breast cancer 
    Carpenco, Ecaterina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cancer research was focused on the studying of proper tumor cells for a long time. Despite the huge progress, there are still a lot of questions, that’s why new molecular markers must be identified. These could ...
  • Tuberculosis characteristics and risk factors in urban compared with rural patients 
    Tihon, Aliona; Tafuni, Ovidiu; Malik, Alina; Niguleanu, Radu; Osipov, Tatiana; Lesnic, Evelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Material and methods: A retrospective selective, descriptive study of socioeconomic, epidemiological peculiarities, case-management, diagnosis and microbiological characteristics of 694 patients with tuberculosis registered ...
  • Inoffensivity of imupurin in pregnancy 
    Pogonea, Ina; Catcov, Carolina; Ghicavîi, Victor (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Determination of imupurin inoffensivity on embryogenesis, organogenesis and teratogenesis in rats. Material and methods: The study of immupurin’s safety during pregnancy was performed on 60 rats, divided into ...
  • Informativity of perinatal medical card in fetal growth assessment 
    Bogonovschi, Eugenia; Bologan, Ion (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Failure to provide antenatal information for pregnant women as well as to complete the perinatal medical records at each visit may have negative effects on the child development. Material and methods: A ...
  • Level of cytokines in patients with pulmonary drug susceptible and resistant tuberculosis 
    Lesnic, Evelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cytokines are the regulators of the immune response in tuberculosis: TNF-alpha and CXCL8 (IL-8) are involved in the granuloma formation, IL-10 inhibits the inflammation; some chemokines increase the liver ...
  • Antibiotic susceptibility and some persistence factors of Gram-negative bacilli isolated from trophic ulcers 
    Balan, Greta (The Scientific Medical Association of the Republic of Moldova, 2019)
    Abstract Background: Infections that are difficult to treat might lead to high morbidity and mortality rates. In some infections, however, despite a proper antibiotic therapy, microorganisms might persist, under certain ...
  • Antiviral therapy in chronic hepatitis C virus infection 
    Rusu, Irina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Hepatitis C is a disease with significant global impact. According to the World Health Organization there are 71 million people chronically infected with the hepatitis C virus. About 399.000 people die each ...
  • Effect of induction of general anesthesia with propofol and fentanyl on hemodynamic response 
    Feghiu, Iuliana (The Scientific Medical Association of the Republic of Moldova, 2019)
    Abstract Background: Induction of general anesthesia with propofol and fentanyl is frequently associated with changes in arterial blood pressure and heart rate. At present, there are no clinical studies investigating the ...
  • The anatomical variations of the posterior circumflex humeral artery 
    Croitoru, Dan; Zorina, Zinaida; Certan, Galina; Galescu, Mihaela; Cerevan, Eugen (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Arteries have a very variable origin, diameter, path, correlation, branching and terminal pattern. An honorable mention is necessary for the individual anatomical variations of the axillary artery branches, ...
  • Interests in knowledge and assistance of epilepsy 
    Cobileanschi, Oleg; Baba, Ludmila; Dandara, Alexandru; Bobea, Alexandru (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Many problems with differential treatment of epilepsy require further clarification. As far as we are concerned, we have developed therapeutic recommendations which, in our opinion, demonstrated to be effective ...
  • Topographico-anatomic peculiarities of the external carotid artery in the perinatal period 
    Slobodian, Oleksandr; Gerasym, Lalita (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: the importance of the given issue is in clarification of ontogenetic transformations of the external carotid artery during the perinatal and early neonatal periods, which is essential from the view of surgical ...
  • Aqueous humor’s biochemical composition in ocular pathologies 
    Iacubitchii, Maria; Bendelic, Eugeniu; Alsaleim, Suleiman (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Being analogous to a blood surrogate, the aqueous humor has an important role in the regulation of the homeostasis of the ocular tissues. It has many functions: provides nutrition, removes excretory products, ...
  • Treatment of inflamed skin wounds with biodegradable polymeric film “Biodep nano” 
    Popadyuk, Oleg; Kutsyk, Roman; Voloshyn, Maryana (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Experimental and clinical studies show that wound healing cannot be evaluated as optimally effective today. For the treatment of wounds today, various methods and means are used. Wound dressing was developed ...
  • Disturbance of bioelectric transmission in carcinogenesis 
    Draguta, Ilarion; Mustea, Anatolie; Popescu, Constantin; Iurcu, Cornel; Palade, Valeriu (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Despite significant financial resources invested in the field of cancer research, there has been a steady increase in the registration of new cases of malignant neoplasms. Modern technical capabilities for ...
  • Lambert-Eaton myasthenic syndrome – a misdiagnosed condition 
    Fala, Paula; Cojocaru, Ina; Chetrari, Larisa; Gavriliuc, Pavel; Sangheli, Marina; Lisnic, Vitalie (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Lambert-Eaton myasthenic syndrome (LEMS) is a rare disorder of the neuromuscular junction. Clinical features include proximal muscle weakness, markedly in the lower limbs, reduced deep tendon reflexes that can ...
  • Sympathetic-parasympathetic cardiac autonomic tonus during induction of anesthesia with propofol and fentanyl 
    Feghiu, Iuliana; Cobiletchi, Sergiu; Sandru, Serghei (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Administration of propofol and fentanyl for induction of general anesthesia is often associated with cardiovascular instability. This effect can be caused by changes in the cardiac autonomic tonus induced by ...
  • The role of cytomegalovirus in the development of opportunistic infections 
    Cirjau, Elena; Behta, Emilia (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: About one century ago, was found and described a new virus, which, due to its particular way of damaging cells, was called cytomegalovirus. Human is the only natural source of cytomegalovirus infection. The ...
  • Translation and validation of the Russian version of the personality inventory for DSM-5 (PID-5) 
    Lozovanu, Svetlana; Moldovanu, Ion; Vovc, Victor; Ganenco, Andrei; Blajevschi, Andrei; Beşleaga, Tudor (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: The 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) has included major and radical changes in the personality disorder (PD) diagnosis method, from categorical to dimensional ...

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