Browsing The Moldovan Medical Journal 2020 by Issue Date

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  • Diagnosis and management of ischemic stroke: time is critical 
    Groppa, Stanislav; Zota, Eremei; Bodiu, Adrian; Gasnas, Alexandru; Manole, Elena; Ciobanu, Natalia; Leahu, Pavel; Efremova, Daniela; Crivorucica, Igor; Glavan, Danu; Balanuta, Tatiana (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: It is predicted that stroke’s incidence and impact will increase considerably over time. Proper management of stroke depends on a reliable and urgent diagnosis that includes patient / relative - emergency team ...
  • The influence of entomological preparations on oxidative stress in subacute inflammation 
    Guțu, Ina (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: It was found out that the development of oxidative stress in the inflammatory processes is determined by the action of harmful factors, as well as by the activity of leukocytes, macrophages, monocytes with the ...
  • Antimycotic activity of phenoxythiazolchloralum 
    Podgornii, Ana; Valica, Vladimir; Pogrebnoi, Serghei; Lupascu, Lucian; Uncu, Andrei; Macaev, Fliur (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: The therapeutic options in invasive candidiasis and aspergillosis are limited and don’t provide expected results. Introducing a new drug in the therapeutic practice can improve the quality of life of ...
  • Inflammatory glaucoma. Elements of etiology and pathology 
    Cușnir, Valeriu; Dumbraveanu, Lilia; Groppa, Liliana; Cușnir, Vitalie; Bobescu, Nicolae; Cușnir, Valeriu Jr. (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Inflammatory glaucoma, also known as uveitic glaucoma is a multifactorial process of inflammation that causes the rising of intraocular pressure (IOP) accompanied by morphological and physiological modifying ...
  • Particularities of ensuring with medicines the patients with rare diseases in the Republic of Moldova 
    Zgircu, Elena (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: To ensure rare disease patients with medicines is a challenge for the health system. Treatments for rare diseases are very expensive, so the main financial burden for providing patients with medicines lies ...
  • Clostridium difficile infection in the intensive care unit 
    Placinta, Gheorghe; Vorojbit, Valentina; Pantea, Victor; Cojuhari, Lilia; Cebotarescu, Valentin; Placinta, Lidia; Croitoru, Dan (The Scientific Medical Association of the Republic of Moldova, 2020)
    Abstract Background: Clostridium difficile (CD) infection is widespread throughout the world, showing an increased incidence over the recent years and may cause severe forms of disease. This infection most commonly affects ...
  • Determination of carotenoids in extracts from species of Tagetes and Calendula 
    Benea, Anna; Ciobanu, Cristina; Cojocaru-Toma, Maria; Ciobanu, Nicolae (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Carotenoids have played a significant role in reducing the risk of chronic diseases. The most studied in this regard is β-carotene, present in species of Tagetes and Calendula genus. Objective of the study: ...
  • Compatibility determination of potassium orotate with spironolactone by high-performance liquid chromatography 
    Mazur, Ecaterina; Schmid, Martin; Uncu, Livia (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Compatibility determination between active pharmaceutical ingredients (APIs) in fixed-dose combinations is an indispensable step in the elaboration. High-performance liquid chromatography provides information ...
  • Immunoexpression of matrix metalloproteinases MMP-1, MMP-2, MMP-9 and MMP-14 in extragenital endometriosis and eutopic endometrium 
    Cazacu, Eugeniu; Zota, Eremei; Margaritescu, Claudiu; Niguleanu, Radu; Pretula, Ruslan (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Matrix metalloproteinases are proteolytic enzymes responsible for the disorder of extracellular matrix modeling in endometriosis and their involvement in the invasion process. The aim of this study was to ...
  • Macrophages and dendritic cells density correlates with depth of invasion in the prostate carcinoma 
    Globa, Tatiana; Globa, Lilian; David, Valeriu; Globa, Pavel; Pelin, Elina; Saptefrati, Lilian (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Immune cells interact not only with tumor cells but also with stromal cells facilitating the progression of neoplasia. The ongoing battle between immune cells and the tumor is an important factor influencing ...
  • Stability studies of isohydrafural and fluocinolone acetonide combined ointment 
    Donici, Elena; Valica, Vladimir; Uncu, Livia (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: The isohydrafural and fluocinolone acetonide combined ointment contributes to the diversification of the treatment of dermatitis and psoriasis associated with bacterial infections. Complex stability studies ...
  • The role of endothelin-1 in the doxorubicin cardiotoxicity 
    Tacu, Lilia (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: The cardiotoxicity of doxorubicin (Dx), an antineoplastic drug, is imposed by the development of cardiomyopathy and heart failure. The expression of endothelin-1 (ET-1) in myocardium under the action of Dx, ...
  • Identifying levels of professional communication language skills training 
    Busuioc, Aliona; Vintu, Victoria (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: The characteristic of the levels of professional communication skills is used by foreign medical students in the formation of the specialized language in Romanian. The professional communication is presented ...
  • Thiol-disulfide metabolism in kidney tissue at the administration of some copper coordination compounds 
    Sardari, Veronica; Pantea, Valeriana; Gulea, Aurelian; Tagadiuc, Olga; Andronache, Lilia; Svet, Inna; Tapcov, Victor; Gudumac, Valentin (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Thiol-disulfide metabolism is essential for normal function of the organism. Thus the interest of the scientists in this area of research continues to grow. Material and methods: Copper coordination compounds ...
  • Isolated renal hydatid cyst in the primary generation of the larval cyst 
    Bernic, Jana; Petrovici, Vergil; Roller, Victor; Curajos, Anatolii; Gudumac, Eva (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: In the Republic of Moldova echinococcosis has a uniform geographical distribution, with an incidence of 10/100000 inhabitants. Renal hydatidosis occupies an important place in surgical pathology. Today’s modern ...
  • Contemporary diagnosis of rhinosinusitis in children 
    Mariana, Turcan; Maniuc, Mihail (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Inflammatory disease of the paranasal sinuses, due to its high incidence in the nosological structure of morbidity, is a constant problem of modern otorhinolaryngology. The purpose of this study was to assess ...
  • Clinical indicators of gait freezing in Parkinson’s disease 
    Gavriliuc, Olga; Andrușca, Alexandru; Gavriliuc, Mihail (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Freezing of gait is a common (FOG) episodic gait disorder in advanced Parkinson’s disease (PD). FOG is one of the main risk factors for falls; therefore FOG’s consequences can be devastating. This symptom is ...
  • Transcatheter aortic valve implantation. First experience of minimally invasive treatment in the Republic of Moldova 
    Abraș, Marcel; Surev, Artiom; Vasa-Nicotera, Mariuca; Moscalu, Vitalie; Grib, Andrei; Popovici, Ion; Beiu, Catalina (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Aortic stenosis (AS) is the most prevalent primary heart valve disease and the third most prevalent cardiovascular disease in the world, having a severe and slowly progressive evolution. The implementation of ...
  • Correlation between nitric oxide levels and clinical features in patients with nasal polyposis 
    Istratenco, Ala (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Nasal polyposis (NP) is a multifactorial pathology with negative impact on quality of life. The pathogenesis of NP has not been fully elucidated. This limits the pathogenic treatment. Recent studies suggest ...
  • Pelvic ring stabilization in the peripartum injuries 
    Kusturov, Vladimir; Ghidirim, Gheorghe; Kusturova, Anna; Paladii, Irina (The Scientific Medical Association of the Republic of Moldova, 2020)
    Background: Parturition-induced pelvic injuries after spontaneous vaginal delivery sometimes happen causing deformation of the pelvic ring. The frequency of these lesions is from 1:300 to 1:30000 births, creating many ...

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