The role of apicle products in ointments formulation

Abstract

Introduction. Now Propolis-containing preparations are widely used in medical practice, due to their bactericidal, antiviral, antifungal, anti-inflammatory, analgesic, regenerative, antioxidant properties. Propolis is a natural preparation, the most powerful anti-infectious drug known, which destroy 21 bacteria, 9 species of parasitic fungi, 30 types of viruses (including their varieties). The development of new pharmaceutical forms containing propolis for the treatment of dermatological diseases is an important research direction in the health branch for Republic of Moldova. According to data estimated by WHO, the prevalence of skin diseases remains a current problem due to the rather high statistical index. Aim of the study. The formulation and efficacy of the preparations with propolis extract in the treatment of skin diseases for adults and children. Completing the information level questionnaires of the population on the efficacy of bee products in medicine. Materials and methods. Synthesis and study of the data of the specialized scientific literature, the results of the population interview, as well as the documentation with magistral prescriptions of the University Pharmaceutical Center (CFU) “Vasile Procopisin”. Results. Propolis is called a "cocktail" of healing substances, gathered from the buds and from the bark of poplars, of birch trees, chestnuts, willows, ash trees, blueberries and some species of fruit trees. In CFU "Vasile Procopisin" ointments were made with propolis extract based on different excipients: Vaseline, lanolin, polyethylene glycols. The pharmaceutical factors that influence the kinetics of the release of the active substance from excipients were analyzed. Population questioning (30 questionnaires) demonstrated the use and efficiency of propolis extract preparations in the treatment of skin diseases and other diseases, as well as a high degree of knowledge of different preparations. Currently, dermatologists from the Health Institutions of the Republic of Moldova prescribe for the treatment of skin diseases soft medicinal preparations with propolis extract, both in the form of industrial preparations and compounded medications. Conclusions. The use of semi-solid preparations with propolis extract gives effective results in the therapy of skin diseases for adults and among children. This offers a higher hope of using natural preparations as compared to those of synthetic origin. The treatment of skin diseases is a complicated complex, which includes an environment of preparations for internal and topical use.