The clinic and paraclinic particularities of systemic lupus erythematosus

Abstract

Introduction. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect any organ or system. It is found in all geographical areas. The incidence is 1: 10000. About 15% of all patients must be diagnosed before 18 years. Women of childbearing age (15- 45 years) are the most affected. Aim of the study. Purpose: To represent the particularities of the systemic disorder in SLE. • Objectives: Elucidation of the incidence of SLE for age and sex groups. Highlighting multiorgan disorders in the case of SLE. Determination of paraclinical changes in SLE. Materials and methods. The present research was focused on studying 94 electronic files of the Hospital Medical Information System (SIA AMS) of the Public Medical-Sanitary Institution Clinical Republican Hospital (IMSP SCR) ”T. Moşneaga ". The discharge records for the year 2019 were selected from the section Atrology and Rheumatology, that had the diagnosis of systemic lupus erythematosus after CIM-10 (code M32). Results. 11% (N = 11) and 83% women (N = 88) were in the study. The average age of the people in the hospital with systemic lupus erythematosus was 51.27 ± 12.43 years. The average diagnostic age of SLE was 44.18 ± 14.22 years. Articular impairment is found in 98%, neurological affects 58%, hematological affects 88%, serositis 29%, skin disorders 89%, kidney damage 65%, double-stranded DNA antibodies detected at 70%. Conclusions. Based on the results obtained, you can conclude that LES is a multi-organ autoimmune disease frequently encountered. The incidence is higher for women. The average age of the patients interned with SLE - 51.27 and those diagnosed - 44.18 years. From a systematic point of view, most frequently encountered is the articular (98%), hematological (88%) and tegumentary (89%) disease.