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Association between essencial hypertension and bone mineral density

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dc.contributor.author Jubran, Rany
dc.date.accessioned 2020-10-21T07:05:16Z
dc.date.available 2020-10-21T07:05:16Z
dc.date.issued 2020
dc.identifier.citation JUBRAN, Rany. Association between essencial hypertension and bone mineral density. In: MedEspera: the 8th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2020, p. 162-163. en_US
dc.identifier.uri https://medespera.asr.md/wp-content/uploads/ABSTRACT-BOOK.pdf
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/12264
dc.description Department of Internal Medicine Rheumatology and Nephrology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova, The 8th International Medical Congress for Students and Young Doctors, September 24-26, 2020 en_US
dc.description.abstract Introduction. With society trending towards aging and unhealthy lifestyle changes the prevalence rate of essential hypertension (EH) and osteoporosis (OP) increases every year, to a point where they have become the two most common diseases in the world. Aim of the study. To highlight the relationship between essential hypertension (EH) and bone mineral density (BMD). Materials and methods. A systematic review on the published literature was conducted. 17 articles on the topic of association between EH and BMD were selected after searching PubMed, Medline, Medscape, and Google Scholar. The data were anaysed and statistically compared . Results. The 17 articles used have a total of 39,491patients. Of these, 13,375 were patients with EH and 26,116 were patients without EH. The most relevant meta-analysis results showed that EH can reduce the BMD of the lumbar spine (95% CI: −0.08∼0.01, P=0.006), femoral neck (95% CI: −0.09∼-0.02, p = 0.001), ward's triangle (95% CI: −0.45∼-0.25, p=0.000), femoral intertrochanteric (95% CI: −0.90∼-0.64, p = 0.000), calcaneus (95% CI: −0.31∼-0.18, p = 0.000) and distal forearm (95% CI: −0.09∼-0.03, p = 0.000), but EH cannot reduce the BMD of the femur rotor (95% CI: −0.07∼0.24, p = 0.273). Another valuable study showed that EH can reduce the BMD of the lumbar spine (95% CI: −0.11∼-0.03, p = 0.000) and femoral neck (95% CI: −0.11∼-0.07, p = 0.000) in Asian populations. In non-Asian populations, EH can reduce the BMD of the femoral neck (95% CI: 0.04∼0.19, p = 0.002), but cannot reduce the BMD of the lumbar spine (95% CI: −0.04∼0.11, p = 0.346). Conclusions. Summarizing the articles and results analysis suggests that EH can have a negative effect on BMD, for different parts of bone, the degree of reduction is different. Furthermore, the reduction level of BMD can vary for different regions and populations. en_US
dc.language.iso en en_US
dc.publisher MedEspera en_US
dc.subject association en_US
dc.subject essential hypertension en_US
dc.subject bone mineral density en_US
dc.subject meta-analysis en_US
dc.title Association between essencial hypertension and bone mineral density en_US
dc.type Article en_US


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  • MedEspera 2020
    The 8th International Medical Congress for Students and Young Doctors, September 24-26, 2020

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