Congresul consacrat aniversării a 75-a de la fondarea USMF „Nicolae Testemițanu”, 21-23 octombrie 2020: Abstract book: Recent submissions

  • Laboratory diagnosis of multiple sclerosis 
    Ichim, Mădălina; Istratenco, Ala (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The complexity of the clinical picture of multiple sclerosis can lead to delayed diagnosis. In this sense, the results of laboratory tests are useful in establishing the final diagnosis, choosing the right ...
  • The role of cerebrospinal fluid biomarkers in Alzheimer’s disease diagnosis 
    Chiriac, Maria; Ticot, Cristina; Andrușca, Diana; Țurcanu, Larisa (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Alzheimer’s disease (AD) is the most common neurodegenerative disorder. As the prevalence of AD increases, the searching for specific biomarker has become increasingly important. The most explored CSF ...
  • The role of autophagy in the evolution of tumors 
    Țurcan, Larisa; Andrușca, Diana; Chiriac, Maria (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Oncological diseases are complex polygenic pathologies in the development of which multiple signaling cascades are involved. Objective of the study. Had been studied the role of autophagy in the human body ...
  • The role of miRNA in acute myeloid leukemia 
    Seu, Sorina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a vital role in the post-transcriptional regulation of gene expression. Deregulated miRNA expression is a prominent feature in acute myeloid ...
  • Micro-RNA (miRNA) aspects in cardiovascular diseases 
    Oboroc, Sandu (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. MiRNA is involved in the evolution of heart diseases through regulation of gene expression with the development of pathological phenotype. Deviations of miRNA expression were described in various cardiovascular ...
  • Biochemical markers of cardiac remodeling 
    Botezatu, Diana; Timercan, Tatiana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Cardiac remodelling is one of the pathogenic pathways leading to heart failure, which occurs due to ischemic, mechanical and inflammatory damage to cardio myocytes and cardiac interstitium. Objective of the ...
  • Cellular-molecular mechanisms in the development of peritonitis 
    Baluțel, Ana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Peritonitis is an inflammatory process involving cells, vascular changes, synthesis of proinflammatory (IL-6, TNF-α) and anti-inflammatory (IL-10, IL-27) mediators which maintain inflammation. The mechanisms ...
  • The role of micro-RNA (miRNA) in development of lymphomas 
    Nica, Loredana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Small miRNA molecules, non-coding, regulate the expression of approximately 2/3 of total human genes, most of which are located in cancer-associated genomic regions. Moreover, in all types of cancer an abnormal ...
  • Changes in vegetative heart tonus after endotracheal intubation during induction of general anesthesia with propofol and fentanyl 
    Smelansky, Emily Ghenady; Feghiu, Iuliana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Induction of general anesthesia, especially the stage of endotracheal intubation is frequently associated with changes in heart rhythm and cardiac arrhythmias triggered by changes in vegetative tonus of the ...
  • Disorders of catalase activity in hypertensive retinopathy 
    Pavlovschi, Ecaterina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The pathobiochemical mechanism of hypertensive retinopathy (HR) is with certainty not established. High blood pressure by itself could not explain the retinal changes that occur, therefore additional pathogenetic ...
  • Indirect lung injury predictive model in experimental trauma 
    Arnaut, Oleg (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Trauma remains a medical-social problem, still having high lethality rate. Indirect lung injury (ILI) occurs in trauma due to systemic neutrophils activation and proteases release into primary intact tissues. ...
  • Challenges in laboratory diagnosis of infection with COVID-19: negative but positive 
    Toma, Alina; Vișnevschi, Anatolie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. As of December 2019, in just 5 months, the new disease (COVID-19) pandemic has expanded to 216 countries and affected more than four million people. This has led to numerous challenges in the laboratory ...
  • Cytogenetic analysis in men with azoospermia 
    Racoviță, Stela; Moșin, Veaceslav; Capcelea, Svetlana; Mișina, Anna; Cemortan, Igor; Sprincean, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. It is estimated that one in six couples are infertile for different reasons, and the male factor is involved in half of the cases. Azoospermia is detected in up to 8% of male infertility situations. The prevalence ...
  • Native vegetable oils: properties and mechanisms 
    Rakovskaia, Tatiana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Vegetable oils with lipophilic compounds (polyunsaturated fatty acids, tocopherols, phytosterols, carotenoids, organic acids, alcohols, esters, aldehydes, ketones) and hydrophilic (phenolic acids, aldehydes, ...
  • Evaluation of the rationality of perioperative antibiotic prophylaxis 
    Coretchi, Ianoș; Garaba, Cristina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Irrational perioperative antibacterial prophylaxis increases microbial resistance, treatment cost, and length of hospital stay. Objective of the study. Evaluation of the rationality of perioperative antibiotic ...
  • Evaluation of serum and tissue nitric oxid levels in patients with nasal polyposis 
    Istratenco, Ala (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Nasal polyposis (NP) - a multifactorial pathology with negative impact on quality of life. The pathogenesis of NP has not yet been fully elucidated. This limits the pathogenic treatment. Recent studies suggest ...
  • The level of knowledge and attitude towards adverse drug reaction reporting 
    Guțanu, Diana; Corețchi, Ianoș; Țurcan, Lucia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The action of drugs is like a balance, on the one side being placed the benefits and on the other the risks. Each drug has a wide range of adverse reactions, so their detection, analysis and reporting have a ...
  • The influence of entomological preparations on oxidative stress in subacute inflammation 
    Guțu, Ina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The role of oxidative stress in the evolution of inflammation is demonstrated. Preparations of entomological origin have revealed antioxidant effect in various pathological processes. Objective of the study. ...
  • Changes of glutathione peroxidase activity in the blood serum on the administration of some local coordination compounds 
    Pantea, Valeriana; Popa, Veaceslav; Fulga, Ala; Șveț, Inna; Tagadiuc, Olga (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Testing of new remedies to correct the redox imbalance are of particular interest. In this aspect an important role is assigned to glutathione peroxidase - the key enzyme, maintaining the optimum level of ...
  • The prognostic value of D-Dimer in COVID-19 infection 
    Martîn, Cristina; Tagadiuc, Olga (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The infection with novel Coronavirus (COVID-19) represents a new form of infection, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Thrombotic complications are manifested paraclinically ...

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