Congresul consacrat aniversării a 75-a de la fondarea USMF „Nicolae Testemițanu”, 21-23 octombrie 2020: Abstract book: Recent submissions

  • Value of some biomarkers of oxidative stress in patients with coraliform nephrolithiasis and chronic calculated pyelonephritis 
    Rotaru, Liliana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Coral nephrolithiasis and chronic calculous pyelonephritis have an important medical and social impact on quality of life and professional or extra-professional performance. Objective of the study. The study ...
  • Carrier frequency of the 35delG mutation in GJB2 gene in the moldavian population 
    Buza, Anastasia; Parii, Sergiu; Butovscaia, Cristina; Galea-Abdusa, Daniela; Curocichin, Ghenadie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The single-nucleotide guanine deletion 35delG in GJB2 exon 2 is the leading pathogenic mutation for up to 70% of cases of congenital nonsyndromic sensorineural hearing loss (NSHL) among Europeans. The early ...
  • Pulmonary embolism syndrome 
    Ursan, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Pulmonary embolism is a common complication of deep vein thrombosis (DVT) or the penetration of amniotic fluid into the maternal circulation. Risk factors include varicose vein disease of the lower limbs, use ...
  • Updates in laboratory diagnosis of primary immunodeficiencies 
    Ivanciuc, Daniela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Primary immunodeficiency disorders (PID) comprise more than 150 disorders that affect the development and/or function of the immune system. PID has the greatest diagnostic burden due to the complexity and ...
  • Role of adipokines in the pathogenesis of atherosclerosis 
    Ostap, Felicia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Obesity is one of the modifiable cardiovascular risk factors. Adipokines, which represent a series of hormones and cytokines secreted by adipose tissue, seem to explain the correlation between obesity and ...
  • Colchicine induced hepatotoxicity: a case report and literature review 
    Caracaș, Anastasia; Vasilache, Eugenia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Colchicine demonstrates the greatest anti-mitotic activity on rapidly dividing tissue and has only infrequently been associated with hepatotoxicity. It has usually been associated with cases of overdose in ...
  • Drug-induced ventricular arrhytmogenesis in patients with COVID-19. A literature review 
    Lablic, Anastasia; Feghiu, Iuliana; Baltaga, Ruslan (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Several existing medications are being repurposed for treatment of COVID-19, including chloroquine and hydroxychloroquine. The use of these medications has been associated with QT prolongation. Their use in ...
  • The role of micro-RNA in fibrinolysis 
    Dumitraș, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Micro-RNAs (miRNAs) were defined as small endogenous non-coding RNAs consisting of 18-24 nucleotides, responsible for the gene expression and involved in many cellular processes. The exact role of miRNA in ...
  • miRNA in oncological pathology: ovarian cancer 
    Pojoga, Maria-Magdalena; Vicol, Adrian (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. miRNAs errors and their defective interference in regulation of gene expression, as well as their long distance action can be correlated with the development and malignization of ovarian cancer, affecting ...
  • The quality of sleep in high school urban students 
    Dumitraș, Mariana; Lupușor, Adrian; Vovc, Victor (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. High school students, in their adolescence age, need at least 8-9 hours of good quality sleep. Their sleeping problems are thought to be due to late melatonin secretion and bad sleep habits, especially in the ...
  • The role of metalloproteinases (MMPS) in tumor development 
    Spoială, Augustina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. MMPs are a family of proteinases that regulate cell behavior by remodeling stromal and cell surface proteins, thereby influencing cell survival, genomic stability, and differentiation. MMPs are key players ...
  • Predictive power of RTS, ASCOT, NISS, ISS and TRISS scores in severe trauma patients from Republic of Moldova. Preliminary data 
    Grabovschi, Ion (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Attempts to predict the evolution course of the pathological conditions led to the traumatic scores’ elaboration based on the distinct medical systems realities that differ in many respects from the local ...
  • The importance of c-reactive protein (CRP) in respiratory infections 
    David, Adrian-Bogdan (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. CRP is a homopentamer protein, an acute phase reactant, present in tissue damage and inflammation. The mechanisms by which it activates the complement, induces apoptosis, phagocytosis, the production of NO ...
  • The role of angiotensin-converting enzyme 2 into the patogenesis of COVID-19 infection 
    Toma, Alina; Vișnevschi, Anatolie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The angiotensin-converting enzyme 2 (ACE2) is an exopeptidase that catalyzes the conversion of angiotensin II to angiotensin 1-7. ACE2 receptor has recently been identified as the entry point of the severe ...
  • Genetic variation of the SCN10A gene in young population of Republic of Moldova 
    Butovscaia, Cristina; Buza, Anastasia; Galea-Abdușa, Daniela; Curocichin, Ghenadie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. PR interval reflects atrial and atrioventricular nodal conduction time, and is an important determinant of arrhythmia risk. Genome-wide association studies (GWAS) have identified association of a nonsynonymous ...
  • The effects of endothelin-1 in doxorubicin disorder of the heart 
    Tacu, Lilia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The cardiotoxicity of doxorubicin, an antineoplastic drug, it is imposed by the development of cardiomyopathy and heart failure. The expression of ET-1 in myocardium under the action of Dx, direct correlates ...
  • Predictive model of treatment result in polytraumatism 
    Arnaut, Oleg (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Assessing the severity of the injuries, as well as estimating the polytrauma patient’s prognosis are the key moments in their management. Predictive models for polytrauma treatment outcome are poorly described ...
  • Molecular and genetic aspects of senescence 
    Pădure, Cătălina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Senescence is the last stage of the physiological development of the human body, in which the cell division stops and the accumulation of damaged cells takes place. Trigger factors are DNA damage, telomere ...
  • Diagnosis of chronic lymphocytic leukemia 
    Motreac, Cristina; Bîcu, Ionela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Chronic lymphocytic leukemia is oncohematological pathologies characterized by the progressive accumulation of monoclonal lymphocytes in blood, bone marrow and lymphoid tissues. In the majority of cases ...
  • Clinical manifestations, diagnostic and contemporary treatment of chronic granulocitary leukemia 
    Ungureanu, Cezara; Plamadeala, Natalia; Dancuța, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Chronic granulocytic leukemia is a chronic myeloproliferative disease characterized by the presence of translocation t(9;22)(q34;q11), also know as the Ph1 and/or BCR-ABL rearrangement. Causal factors remain ...

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