Conferinţa ştiinţifică anuală "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță", 2021: Recent submissions

  • Perspectives for use of a new unsaturated derivative of 1,2,4–triazol with antifungal and antibacterial action–nitrotriazone 
    Drumea, Maria; Valica, Vladimir; Uncu, Livia; Macaev, Fliur; Crudu, Valeriu (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. 1,2,4-triazole derivatives show increasing interest in the development of antifungal and antibacterial drugs. Due to their dipole character and ability to bind hydrogen, triazoles act as pharmacophores by ...
  • Sepsis: current challenges and new solutions based on modern technologies. A clinical management approach 
    Iapăscurtă, Victor; Belîi, Adrian (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background: Despite high associated mortality and high treatment costs, sepsis remains difficult to diagnose, particularly viral sepsis in COVID-19 infection with bacterial coinfection. A recent supplement to sepsis ...
  • Application of ultrasound in patients with kidney diseases 
    Sabeena, Mohammed Suhail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The use of ultrasound in nephrology has been on the increase in recent years. Doctors are increasingly performing ultrasonography, which has applications including investigations of the kidneys and lower ...
  • Role of epicardial adipose tissue in the pathogenesis of atrial fibrillation 
    Ostap, Felicia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Clinical studies revealed the correlation between epicardial fat volume and atrial fibrillation risk.This fat depot located between the myocardium and the visceral pericardium, due to the proximity to the ...
  • Evaluation of the impact of work-related stress on anesthesiologists and intensive care physicians 
    Tăzlăvan, Tatiana; Popili, Mihail; Ambrosii, Tatiana; Feghiu, Iuliana (Universitatea de Stat de Medicină și Farmacie ”Nicolae Testemițanu” din Republica Moldova, 2021)
    Background: Work-related stress is a major problem for employees and society. It is the second most common work-related health problem and affects 40 millions people in the European Union. Objective of the study. The ...
  • Association of pulmonary tuberculosis and COVID-19 
    Gamaniuc, Marina; Veselovskaia, Ana; Vișnevschi, Anatolie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The World Health Organization (WHO) estimated in 2019 10 million cases of tuberculosis (TB) with 1.6 million deaths worldwide. Since 2020, COVID-19 is a respiratory disease that has spread globally with ...
  • Features of injection drug users diagnosed with tuberculosis 
    Cotelea, Eugeniu; Mahamid, Uday Amir (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Injection drug users (IDUs) are among of the high risk to be screened for TB annually in the Republic of Moldova. It is due to their features which maintain them to be hard-to-reach for detection, treatment ...
  • Calcifying pulmonary nodules – clue to an alternative diagnosis 
    Bradauțan, Adela; Calaraș, Diana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Considering the high burden of TB in our country, a calcifying lung nodule on a chest X ray or chest CT is traditionally interpreted as a TB sequela. In reality calcium accumulation in the lung parenchyma or ...
  • Selection of optimal parameters for the analysis of dioxoindolinone by the method of high pressure liquids chromatography 
    Ștefaneț, Tatiana; Chirița, Cornel; Valica, Vladimir (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Anxiety and depression are among the most common mental disorders worldwide. Thus, the search for and obtaining new compounds used in the treatment of mental disorders is an important research topic, as well ...
  • Principle of formulation of circadian release medicines 
    Ciobanu, Cristina; Guranda, Diana; Ciobanu, Nicolae; Diug, Eugen; Solonari, Rodica (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Rheumatoid arthritis is a chronic disease that causes inflammation of the joints and surrounding tissues. To anticipate morning joint stiffness, chrono-therapeutic systems have been designed that adjust the ...
  • Features of tuberculosis in labour migrants from Chisinau, the Republic of Moldova 
    Zaid, Lafee; Abadi, Ahmad Reyad (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. In high TB burden countries, such as Moldova, TB is mostly diagnosed in young people from high risk groups including the migrant workers. Objective of the study. The aim the assessment of the general ...
  • Particulars of diagnosis and surgical treatment of patients with Mirizzi syndrome 
    Cucu, Ivan; Hotineanu, Adrian; Ferdohleb, Alexandru; Cazac, Anatol; Cazacu, Dimitru (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background: Mirizzi syndrome (SM) is a late and rare complication in the evolution of gallstones, morphologically translated by compression of the hepato-choledochus with stricture formation at this level or cholecysto-biliary ...
  • Application of design of experiments in pharmaceutical analysis 
    Donici, Elena; Crețu, Dionisie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The quality of a drug should be design during the analytical development. Design of experiments are widely used to determine the influence of factors on the output responses of analytical methods. There are ...
  • The erythrocytes’ catalase activity is influenced by Taraxacum officinale 
    Protopop, Svetlana; Fulga, Ala (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The cells developed a series of antioxidant agents, which protect against harmful effects of H2O2. Taraxacumofficinale F. H. Wigg (TO) represents an important source of biologically active substances, whose ...
  • Chemical study of genotypes of Origanum vulgare ssp. vulgare l. and origanum vulgare ssp. Hirtum (Link) Ietswaart from the Republic of Moldova 
    Pompuș, Irina; Benea, Anna; Babina, Iulia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Origanum vulgare, a medicinal and aromatic species is important due to its antibacterial, antioxidant, antiviral, antifungal properties, supported by the complex chemical composition. In the Republic of Moldova ...
  • Dual-guidewire technique of ERCP in difficult biliary cannulation 
    Pitel, Eleferii (Universitatea de Stat de Medicină și Farmacie ”Nicolae Testemițanu” din Republica Moldova, 2021)
    Background: Acute pancreatitis (AP) is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP), and develops in up to 15% of cases. Difficult biliary cannulation is a recognized technical ...
  • In vitro testing of influence of some bioactive compounds on the protein and carbohydrate metabolism indices 
    Sardari, Veronica; Pantea, Valeriana; Garbuz, Olga; Andronache, Lilia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. New data were obtained on the molecular mechanisms of antiproliferative, antiinvasive, antiangiogenic, vasoprotective, antiatherogenic, antioxidant and anti-inflammatory action exerted by bioactive compounds ...
  • Imaging presentation of the orbital dermoid 
    Romanciuc, Anastasia; Păduca, Ala; Tudos, Silvia; Basova, Svetlana; Cepoida, Elena (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Orbital dermoid is a congenital benign cystic teratoma (choristoma) that originates from aberrant ectodermal tissue, displacement along embryonic lines of closure, when the suture lines of skull close, epidermal ...
  • Contemporary approaches in photodermatosis 
    Polizo, Antonina; Nedelciuc, Boris (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The most important skin diseases, produced by photoaggression and / or photosensitization, can be divided into 5 large groups: 1) phototraumatic dermatoses; 2) photoallergic dermatoses; 3) photodynamic ...
  • Renin-angiotensin system, SARS-CoV-2 infection and ocular pathology 
    Bacinschi, Andrei (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The ocular local renin-angiotensin system (RAS) play a significant role in proliferation, angiogenesis, and apoptosis. The presence of angiotensin-converting enzyme 2 and transmembrane serine protease 2 in ...

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