Conferinţa ştiinţifică anuală "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță", 2021: Recent submissions

  • Minimally invasive surgery approach in case of solitary aortic defect 
    Cretu, Stefan; Rotaru, Adrian (Universitatea de Stat de Medicină și Farmacie ”Nicolae Testemițanu” din Republica Moldova, 2021)
    Background: Mini-sternotomy for plastic surgery or isolated aortic valve replacement requires rapid recovery with diminished convalescence time, improved cosmetic outcome and lower hospital costs. The basic clinical ...
  • Diastolic disorder inherent to Doxorubicin cardiotoxicity 
    Tacu, Lilia; Cobeţ, Valeriu (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Doxorubicin (Dx), antibiotic of anthracycline group, used with predilection in treatment of oncologic diseases, often results in cardiotoxicity manifested by endangering diastolic relaxation, which requires ...
  • Management of polytraumatized patients with dominance of the locomotor 
    Pascari, Vasile; Moșneguțu, Serghei; Malacinschi-Codreanu, Tatiana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Polytraumas represent approximately 16% of all traumas and are burdened by a still high mortality (15-50%), being the main cause of death in the population under 40 years and the third cause of death at all ...
  • Optimization of the surgical management of gastric cancer 
    Bortă, Eduard; Hotineanu, Adrian; Burgoci, Serghei (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background: The stomach IS one of the most frequently localization of malignant neoplastic disease in the digestive tract. The incidence of gastric cancer is declining in the world, but it remains very high, occupying the ...
  • The particularities of tuberculosis in early children 
    Abu, Arar Omran (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Diagnosis of TB in early age children is very difficult, due to the evolution of TB in the form of various masks of other diseases, rapid spread of the infectious process, diversity of forms of TB, increasing ...
  • Contemporary aspects in aortocoronary by-pass on beating string 
    Plataș, Victor; Morozan, Vladislav; Barnaciuc, Sergiu; Cheptanaru, Eduard; Bostan, Ghenadie; Guzgan, Iurie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background: The tendency to minimize the intra- and postoperative danger led to the implementation of the method of revascularization of the myocardium on the beating heart. Some authors consider that compared to traditional ...
  • Phenolic compounds of Lavandulae angustifoliae Mill. residues 
    Cojocaru-Toma, Maria; Vameș, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Lavandula angustifolia Mill. is a species of the family Lamiaceae, native to the Mediterranean Basin, which shows antibacterial, antifungal, carminative, sedative and antidepressant effects, based on acyclic ...
  • Biochemical mechanisms of insulin resistance 
    Condrea, Cătălin; Sardari, Veronica (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The mutation of the Insulin Receptor Substrate-1 gene is a cause for insulin resistance. The mutations is due to the replacement of Gly with Arg at codon 972, which leads to the formation of a defective protein ...
  • Optimization of magistral semi-solid forms used in urogenital diseases 
    Guranda, Diana; Ciobanu, Cristina; Ciobanu, Nicolae; Solonari, Rodica (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Urinary tract infections are the most common urogenital diseases, with an increased incidence in women and the elderly. Urogenital infections are caused by Gram-negative germs, in which E. coli predominates ...
  • Validation of the spectrophotometric method for the dosing of some combined capsules 
    Uncu, Livia; Evtodienco, Vladilena; Mazur, Ecaterina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. UV spectrophotometry remains the most accessible spectral method, with a high degree of sensitivity and informativeness. The advantage of the method consists in its universality, the ability to combine with ...
  • Features of the pediatric patients with tuberculosis 
    Haj, Tamer Yusuf; Ghelis, Iulia; Abadi, Ahmad Reyad (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The receptivity for TB is higher during the childhood period due to social, epidemiological and biological risk factors. Objective of the study. To establish the peculiarities of pediatric patients diagnosed ...
  • Rosavin and salidroside content in extracts from rhizomes of Romanian Carpathian population of Rhodiola rosea L. 
    Călugăru-Spătaru, Tatiana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. R. rosea L. is a valuable medicinal plant. Due to its precious properties it is intensively collected and is on the verge of extinction. The active components, such as rosavin and salidroside, accumulate ...
  • Iron deficiency in Restless Leg Syndrome Willis-Ekbom 
    Goian, Daniela; Lupușor, Adrian (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Restless Leg Syndrome (RLS) is recognized as a neurological disorder characterized by abnormal sensations in the legs, that can cause insomnia. Its prevalence in the general population is between 5.5% and ...
  • Medico-surgical approach to recurrent non-cirrhotic bleeding esophageal varices 
    Cazacov, Vladimir; Iliadi, Alexandru; Focșa, Alexandru; Lisnic, Natalia; Găină, Cristina (Universitatea de Stat de Medicină și Farmacie ”Nicolae Testemițanu” din Republica Moldova, 2021)
    Background: The management of the patient with digestive hemorrhage from esophageal varices represent a real challenge for the multidisciplinary team and encompass a broad spectrum of therapeutical gestures. Objective ...
  • Magnetic nanoparticles in the detection of SARS-CoV-2 virus 
    Fiodorova, Svetlana; Diug, Eugen; Ciobanu, Nicolae; Guranda, Diana; Ciobanu, Cristina; Anton, Mihail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The new COVID-19 infection, caused by the SARS-CoV-2 virus, has hit the global health care system due to its rapid spread from person to person. A prompt and accurate detection method is crucial in detecting ...
  • Features of the COVID-19 patients hospitalised in the Municipal Hospital of Phthisiopneumology, Chisinau, Republic of Moldova 
    Ungurean, Andrei; Lesnic, Evelina; Malic, Alina; El Abiat, Gamil Ali; Osipov, Tatiana; Kulcitkaia, Stela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The evolution of the COVID-19 patients is characterized by the poliorganic involvement in 5% of the patients and with mild evolution in more than 2/3 affected patients. Objective of the study. The evaluation ...
  • Monoclonal antibodies in SARS-CoV-2 infection therapy 
    Ananco, Alexandru; Diug, Eugen; Ciobanu, Nicolae; Guranda, Diana; Ciobanu, Cristina; Anton, Mihail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Immunotherapy has its potential in the treatment of various infectious diseases. Monoclonal antibodies (mAbs), in particular, represent a relatively new approach in the therapy of SARS-CoV-2 infection. Objective ...
  • New technologies in the development of anti-COVID-19 vaccines 
    Sîrbu, Inesa; Diug, Eugen; Ciobanu, Nicolae; Guranda, Diana; Ciobanu, Cristina; Anton, Mihail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The COVID-19 pandemic as presented unique challenges for the development of modern technologies for large-scale vaccine production. Such an urgent need for a new vaccine has led to a significant reduction in ...
  • Pharmacological properties of direct factor Xa inhibitors 
    Oboroc, Sandu (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Severe and critical COVID-19 complications include embolism or pulmonary thrombosis, hypercoagulable state, following pathological mechanisms: activation of coagulation factors, decreased anticoagulant and ...
  • Characteristics of infiltrative pulmonary tuberculosis cases (Caseous pneumonia) 
    Rafe, Marian Mohammad (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Caseous pneumonia is included in acute progressive form of pulmonary tuberculosis which usually affects multiple segments, either unilaterally or bilaterally. The clinical picture of caseous pneumonia is ...

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