Resections in advanced pancreatic, colon and gastric cancer

Abstract

Introduction : The prognosis for life in patients with locally advanced malignant tumors is extremely poor in any primary location. The invasion of adjacent organs and trunk vessels over the decades has been considered unresectable for technical reasons and also for oncological radicalism. The aggressive surgical approach will extend the limits of the resection and in the association of perioperative chemotherapy can provide greater survival in this patient population. Material and methods: We analyzed 54 patients with locally advanced malignant tumors with invasion in neighboring organs, which underwent multivisceral resections. From the total group 12 patients were diagnosed with gastric cancer, 24 patients with colorectal cancer, 18 patients with pancreatic cancer. Results: R0 resection was achieved in 86% of cases. Postoperative morbidity 7.4%, morbidity 21.4% and are directly proportional to the number of anastamosis performed in stages of reconstruction. Conclusions: The morbidity and mortality of multiorganic resections is significantly higher than standard resections, therefore requires careful selection of patients for aggressive surgical approach. Multivisceral resections have curative potential and are feasible in R0. Overall survival in locally advanced in IV stage for patients after multivisceral resection is much longer than patients after palliative treatment.