Abstract:
Introduction:
Since the beginning of the COVID-19
pandemic, an increasing number of patients
with Transient Global Amnesia (TGA) was
attested in neurological emergency
departments [1,2].
However, there is limited data on the
mechanism of TGA linked with COVID-19,
in the convalescence period.
Purpose: To analyze the possible
linkage between SARS-CoV-2 infection
and TGA in two patients, during the
convalescence state.
Material and methods: 2 clinical
cases of TGA, manifested during the
convalescence period of the COVID19 infection.
Results
Case no. 1
A 62-year-old man, that suffered a
mild form of COVID-19 infection
in February 2021, he presented an
episode of TGA within one month.
Brain MRI was normal.
Case no. 2
A 68-year-old man with TGA, 4 months
after a severe COVID-19 pneumonia.
Fronto-temporal, bilateral, cerebral
atrophy was established on brain MRI.
Conclusions: Novel coronavirus may be implicated in
possible pathophysiological mechanisms, involving the
frontal and temporal lobes, which might trigger TGA.
Further studies are required.
Description:
“Nicolae Testemitanu” State University of Medicine and
Pharmacy, Residency Faculty, Department of neurology no.2,
Chisinau, Republic of Moldova, Institute of Emergency Medicine, Clinical Department of
Neurology, Epileptology and Internal Disease, Chisinau, Republic
of Moldova
