Abstract:
Introduction: Among the rheumatic diseases osteoarthritis ranks first in the world and is the second
spread ailment after ischemic heart disease and cerebrovascular disease in Europe (Kovalenko V. M.,
2009). The gradual development of osteoporosis and its invisible clinical signs lead to disease progression
and severe consequences. Involutive and pathological changes in cartilage and bone tissue lead to the
development of osteoarthritis and osteoporosis which are interconnected, inter-processes and progress
with age and are parallel.
Aims: The purpose of the work was to stress the impact of osteoarthritis duration on the bone mineral density. To achieve this goal, we examined 87 patients with primary osteoarthritis (OA), aged from
35 to 76 year (57,28 ± 2,2 year), where women predominate.
results. The average duration of osteoarthritis was (7,56 ± 1,02 year). Osteopenic syndrome was diagnosed in 41,38% (n = 36) patients, among which 11 patients were diagnosed with primary osteoporosis.
Results: Study of osteoarthritis disease duration influences basic densitometric parameters of the
bone showing reliable differences between groups of patients with disease duration below 5 years and
over 10 years.
Bone mineral density decreases consequently with increasing of osteoarthritis disease duration, in
the group with duration of OA over 10 years it is (0, 826 ± 0,04) g/cm2, which is 14, 32% less than in the
group with duration of disease below 5 years and by 10, 02% less than in the group with disease duration
from 5 to 10 years.
Indicator Young - Adult was less in patients with disease duration more than 10 years - (70,33 ±
3,38)%, which is 13, 30% less than in patients with disease duration below 5 years and 7.43% percent less
than in patients with disease duration from 5 to 10 years.
The percentage patient’s BMD deviation from the average population rate is the lowest in patients
with a osteoarthritis duration more than 10 years and is (75,67 ± 4,98%), which is 13, 58% less than in the
group with duration of the disease of «1 - 5 years» and by 11, 37% less than in the group with the duration of disease of «5 -10 years.»
Conclusion: Summarizing we can say that the degree of bone demineralization increases consequently with duration of OA disease.
