Abstract:
Introduction. Venous trophic ulcers are a common clinical entity, affecting 0.3% - 1% of the adult
population, being associated with a significant reduction in quality of life. Most studies note the
predominance of females, the ratio of women:men ranging from 1,5:1 to 10:1. The treatment is lasting,
often with low efficacy, a high recurrence and requires a multidisciplinary approach.
Case presentation. A prospective study was conducted on 5 patients with venous trophic ulcers, associated
with hypertension, treated in Septic Surgery Department (IMU) during 2021. Patient selection criteria:
active venous ulcer, adults>18 years, administration of topical treatment. The treatment with DibuCell
Active was performed according to the scheme proposed by the manufacturer without any other local
treatment. The dynamics of epithelialization of the ulcers and duration of treatment was analysed. The
surface dynamics of ulcers was evaluated by using computerised analysis of digital images according to the
ImageJ program.
Discussion. According to the duration of treatment and the size of the ulcer, the patients were divided into:
I lot (ulcer<5cm2) complete epithelialization in 20 days – 2; II lot (ulcer - 5-10cm2) complete
epithelialization in 30 days – 2; III lot (ulcer >10cm2) complete epithelialization in 90 days – 1.
Conclusion. The new therapeutic approach in the control of chronic venous ulcers - the biodegradable
dressing DibuCell Active has a major effectiveness by increasing epithelialization and reducing the duration
of treatment. Also, the biodegradable dressing DibuCell Active, minimises the trauma of the newly formed
granules and ensures an optimal environment for increase of the healing.
