Abstract:
Summary.
Aim: evaluation of respiratory syndromes found in children with primary
immunodeficiencies.
Methods: in the study, were evaluated 14 children with primary
immunodeficiencies, diagnosed in the Pneumology Clinic of IMSP Mother and Child
Institute. The patients in the study were divided according to the type of PID. The
patients were evaluated by methods: determination of serum Ig, determination of
cellular immunity, imaging examination of the chest by Rx or CT.
Results. Of 14 patients evaluated in study, 46.8% were diagnosed with primary
immunodeficiencies due to antibody deficiency, and 53.2% presented with combined
primary immunodeficiencies (PID). Pulmonary infections, especially pneumonia, were
the most common clinical manifestations in all patients with PID. Until the
establishment of the diagnosis all patients (100%) present at least one episode of
pneumonia, the number of episodes being directly proportional to the age of the
diagnosed.
Conclusion: Complications of respiratory system diseases are frequent in primary
immunodeficiencies in children, PID due to antibody deficiency being mainly
associated with irreversible bronchopulmonary processes, with severe evolution.
