1. COLECȚIA INSTITUȚIONALĂ: Recent submissions

  • Impact of climate change on cardiovascular outcomes 
    Gordaș, Cătălin; Manic, Milena; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cardiovascular disease (CVD) remains a leading cause of global morbidity and mortality, through an interplay between climate change and the prevalence, progression, and prevention of CVD. In late years, a ...
  • Immunohistochemical particularities as prognostic factors in diffuse large B-cell non-Hodgkin lymphoma 
    Dudnic, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diffuse Large B-Cell Lymphoma (DLBCL), the most common type of NonHodgkin Lymphoma (NHL) globally, is classified into two distinct biological categories based on the gene expression profile (GEP): the germinal ...
  • Genetic aspects of migraine 
    Morari, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Migraine is a common neurological disorder which affects 15–20% of the population and usually begins at puberty, but has the greatest impact on people aged 35 to 45 years. Migraines present a severe headache ...
  • Incidence, risk factors, and complications of cardiovascular system in patient with Graves disease 
    Saravanane, Essaimathi (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Graves' disease, a common autoimmune illness characterized by a rise in thyroid hormone production, has been widely researched in terms of its effects on the thyroid gland. However, a new study emphasizes the ...
  • Autism spectrum disorder - a comprehensive literary review 
    Lupașcu, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Autism spectrum disorder (ASD) can be identified from other neurodevelopmental disorders by its distinctive combination of symptoms: difficulties in social interaction and communication, repetitive, stereotyped, ...
  • Secondary prevention of sudden cardiac death in patient with ischemic heart disease 
    Pruteanu, Albert (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sudden cardiac death (SCD) is the cause of about ½ of all cardiovascular deaths, while up to 50% is the first manifestation of heart disease. The annual incidence of SCD increases with age, so in the eighth ...
  • Treatment of Hodgkin’s lymphoma in advanced stages 
    Marandici, Daniel; Musteață, Larisa; Musteață, Vasile (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hodgkin's lymphoma is a relatively frequent neoplasm of the lymphatic system representing one of the most common types of cancer in young adults. Hodgkin's lymphoma is an aggressive, clinico-pathologically ...
  • The medical rehabilitation program improves the quality of life of patients with AMI 
    Badan, Maxim; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The incidence of acute myocardial infarction (AMI) is continuously increasing. In 2019, mortality from cardiovascular diseases reached 9 million people each year in Europe. Cardiovascular diseases are the ...
  • Unraveling the molecular signaling pathways in glial tumors with methylated MGMT promoters 
    Croitoru, Dan; Andronachi, Victor; Andrușca, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Most gliomas are typically assessed using imaging methods. A recent advancement in this regard involves the integration of biomarkers in conjunction with imaging techniques, such as 18F-FDG-PET-based radiomics ...
  • Key non-receptor tyrosine kinases in adaptive immunity 
    Osoianu, Inesa (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-receptor tyrosine kinases (NRTKs) are cytosolic enzymes, grouped together as a subclass of protein tyrosine kinases (TKs) due to their lack of an extracellular and transmembrane domain, unlike receptor ...
  • The clinical value of enthesitis in the early diagnosis of psoriatic arthritis 
    Melnic, Nicolae (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Joint diseases are one of the most common chronic diseases of society, and one of the most common is psoriatic arthritis (PsA), which is differentiated by a high incidence of enthesitis. Aim of study. ...
  • Dietary habits of patients with ischemic heart disease 
    Abraș, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ischemic heart disease continues to be the leading cause of mortality, morbidit y and high hospitalization rates in both high-income and developing countries. According to data from the World Health Organization, ...
  • Awareness of stroke– degree of patients concern regarding this condition 
    Babii, Regina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. One in four people will suffer a stroke in their lifetime, so stroke can affect all of us. The person who develops a stroke needs ultra-fast access to the medical facility able to provide him specialized ...
  • The peculiarities of the psychological profile in the perinatal period in pregnant adolescents 
    Valache, Mădălina; Budianu, Cătălina; Leșco, Dorina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The mental health of pregnant women has long been a focus of reproductive health. Pregnant adolescents, being an important link, are at greater risk of developing reproductive health problems. To be able to ...
  • Tiny seeds, mighty struggles: pregnancy evolution in intrauterine growth restriction 
    Manic, Milena; Budianu, Cătălina; Coșpormac, Mihaela; Vicol, Maria-Magdalena; Bubulici, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intrauterine Growth Restriction (IUGR) represents a very serious yet often silent threat to fetal and neonatal welfare, manifesting as a rate of fetal growth below the expected norm for a given infant. IUGR ...
  • The principles of the "fast track" program in obstetrical emergencies 
    Vasilachi, Cristian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Currently, the trend of contemporary surgery is to ensure a perioperative result of an increased quality, with the reduction of the stressful impact of the surgical act on the internal homeostasis of the human ...
  • Vaginal cones with vibrating ball inside in pelvic floor dysfunction 
    Villani, Federico; Rigano, Damiano; Moratti, Elisabetta; Minopoli, Bruno; Guglielmino, Alessandra; Todut, Oana; Ciobanu, Victoria; Furau, Roxana; Furau, Cristian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. These are the first results of an ongoing multicentrum observative trial to determine the effectiveness of vaginal cones (VC) in pelvic floor (PF) training. Because of a high economic burden of urine incontinence ...
  • The role of endometrial biopsy in the diagnosis of endometrial hyperplasia 
    Lavric, Irina; Burac. Mihaela; Prepelita, Madalina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Endometrial hyperplasia (EH) is a pathological process of the uterine mucosa characterized by gland proliferation and an increase in the gland-stromal ratio, which develops as a result of excessive estrogenic ...
  • Unintended pregnancy despite IUD, complicated with huge fibroid and scarred uterus, a rare case report 
    Marin, Dimitris; Ciobanu, Victoria; Henegariu, Irina; Furău, Cristian; Furău, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Unintended pregnancy rates remain high as a percentage in adolescents, socioeconomic groups and women that are already closed to the familiar planning. Thus, the variety of contraception methods are increasing ...
  • The influence of pregnancy on the evolution of uterine myoma 
    Guţu, Laura; Găină, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Uterine myoma is a benign, hormone-dependent tumor that occurs more frequently in women aged 25-45. It comprises 30-35% of all gynecological diseases with a correlation between pregnancy and uterine myoma. ...

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