„Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025: Recent submissions

Now showing items 1-20 of 35

Fecal microbiota transplantation in cirrhosis: a microbiome-based therapeutic revolution

Marcu, Beatrice; Sardari, Veronica (CEP Medicina, 2025)

Introduction. The gut microbiota, as well as the gut-liver axis, play a significantly important role in the fibrosis process. As fibrosis progresses to cirrhosis, it further worsens the microbiota, creating a vicious cycle ...
Q-SPECT CT in the assesment of post-pulmonary embolism complications: a new perspective on risk stratification and management

Ivanes, Igor; Sorici, Galina; Cîvîrjîc, Irina; Diaconu, Nadejda; Grosu, Aurel; Gorohova, Marina; Ivanes, Anastasia; Plugaru, Ana; Ambroci, Rada; Cărăuș, Victoria; Lupu, Diana; Rusanovschi-Balica, Olga; Surev, Artiom (CEP Medicina, 2025)

Introduction. Pulmonary embolism (PE) is a severe cardiovascular condition associated with significant morbidity, often resulting in long-term complications despite adequate anticoagulation. Chronic thromboembolic pulmonary ...
The role of glycation processes in aging

Ghinda, Daniela; Sardari, Veronica (CEP Medicina, 2025)

Background. Glycation is a non-enzymatic reaction in which reducing sugars react with free amino groups in proteins, lipids, or nucleic acids, leading to the formation of advanced glycation end products (AGEs). AGE ...
Review of literature on combined liver elastography techniques

Calistru, Natalia; Țarălungă, Tatiana; Harti, Aliona (CEP Medicina, 2025)

Background. Liver elastography has become a pivotal non-invasive method for assessing liver fibrosis, offering an alternative to traditional biopsy. Techniques such as transient elastography (TE), point shear wave ...
Lienal vein – hemodynamic aspects in portal insufficiency

Cobîleanschii, Eugeniu; Cobîleanscaia, Liubov (CEP Medicina, 2025)

Introduction. The length of the lienal vein is 8–12 cm; caliber 6–12 mm, rectilinear trajectory. The lienal vein traverses the border of the pancreatic body, then joins the superior mesenteric vein at the pancreas neck ...
The capacity of hepatic henodynamics in the nutritional assurance of hepatocytes in the elderly

Cobîleanschii, Eugeniu; Cobîleanscaia, Liubov (CEP Medicina, 2025)

Introduction. Blood supply to hepatocytes is severely compromised as a result of the difficult exchange of substances between hepatocytes and plasma, by the continuous deposition of collagen in the space of Disse, ...
Hemodynamic indicators in the superior mesenteric vein in patients with hepatic cirrhosis

Cobîleanschii, Eugeniu; Cobîleanscaia, Liubov (CEP Medicina, 2025)

Introduction. Blood from the small intestine drains through the superior mesenteric vein. Defective blood flow, caused by hemodynamic deviations, lead to intestinal ischemia. Under these conditions, the cells of the ...
Correlations between echocardiographic findings and SPECT CT as a predective tool for chronic thromboembolic pulmonary hypertension in post-pulmonary embolism patients

Sorici, Galina; Diaconu, Nadejda; Civirjic, Irina; Ivanes, Igor; Gorohova, Marina; Plugaru, Ana; Grosu, Aurel (CEP Medicina, 2025)

Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe but potentially treatable complication of pulmonary embolism (PE). SPECT CT has emerged as a non-invasive modality capable of detecting residual ...
Molecular mechanisms of neuronal aging and neurodegeneration

Demidova, Inga; Șaptefrați, Lilian (CEP Medicina, 2025)

Background. Aging of the nervous system is accompanied by complex molecular changes that contribute to the development of neurodegenerative diseases. Understanding these mechanisms is crucial for developing effective ...
The role of endothelins in cancer progression: recent insights and therapeutic opportunities

Cazacu, Felicia; Sardari, Veronica; Munteanu, Roman; Rudic, Ciprian; Tagadiuc, Olga (CEP Medicina, 2025)

Background. Endothelins (ETs) and their receptors (ETAR and ETBR) play a significant role in cancer progression, influencing processes such as proliferation, invasion, and metastasis. The endothelin axis contributes to ...
Mitochondrial calcium regulation in Alzheimer`s disease

Casian, Andreea; Sardari, Veronica (CEP Medicina, 2025)

Background. Calcium ions (Ca²⁺) play an essential role in neuronal function, contributing to synaptic transmission, interneuronal communication, and neuroglial interactions. Mitochondria regulate the intracellular ...
Telomere shortening as a mechanism for the induction of neurodegenetative diseases

Casian, Andreea; Sardari, Veronica; Stratulat, Silvia; Munteanu, Roman; Cojoc, Daniela; Tagadiuc, Olga (CEP Medicina, 2025)

Background. Telomeres are considered the "cellular biological clock" because their length could determine the possible number of cell divisions. Telomerase plays a role in maintaining telomere length. Telomerase ensures ...
Review: the role of color Doppler ultrasound in the evaluation of thyroid nodules

Calistru, Natalia; Țarălungă, Tatiana; Vangheli, Ludmila (CEP Medicina, 2025)

Background: Thyroid nodules are commonly detected in clinical practice, with a significant portion being benign, but a small percentage harbor malignancy. Accurate evaluation of these nodules is crucial for guiding ...
Nasal permeability in inflammatory rhinosinusal diseases in children

Maniuc, Mihail; Danilov, Lucian; Ababii, Polina; Nacu, Viorel; Furculița, Daniel; Bugan, Maria; Crețu, Carolina; Vishnumaya, Sureshan (CEP Medicina, 2025)

Introduction: Rhinosinusal inflammatory diseases constitute a current problem of contemporary rhinology. Rhinitis, sinusitis seriously affect the physiological functions of the nose, including the most important of them, ...
Correlation between CD45 expression and clinical-pathological variables in invasive ductal breast carcinoma associated with type 2 diabetes mellitus

Brînza, Dumitru (CEP Medicina, 2025)

Introduction. This study investigates the correlation between CD45 expression and clinicalpathological variables in invasive ductal breast carcinoma associated with type 2 diabetes mellitus. CD45, an immune regulator, was ...
Neuroprotective effects of ethanolic extracts from Solanum macrocarpon in a zebrafish model of scopolamine-induced Alzheimer's disease-related dementia

Brînza, Ion; Guliev, Corina A.; Oluwabukola Oresanya, Ibukun; Nazli Gok, Hasya; Erdogan Orhan, Ilkay; Hrițcu, Lucian (CEP Medicina, 2025)

Introduction. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and oxidative stress. Natural bioactive compounds with antioxidant and neuroprotective properties have ...
Anatomical variability of the deep femoral artery

Botnaru, Doina; Zorina, Zinovia; Babuci, Angela; Catereniuc, Ilia; Botnari, Tatiana (CEP Medicina, 2025)

Introduction: The deep femoral artery (DFA) serves as a crucial „turning point” between collateral circulation of the pelvis and that of the lower limb (LL), playing a determinant role not only in femoropopliteal axis ...
Variability of the paired visceral branches of the abdominal aorta

Botnari, Tatiana; Babuci, Angela; Zorina, Zinovia; Catereniuc, Ilia; Botnaru, Doina; Ostahi, Nadia (CEP Medicina, 2025)

Introduction: The demand for an individualized approach in interventional surgery of abdominal cavity organs has recently increased. Due to various surgical techniques and large number of surgeries, including kidney ...
Specific features of the facial nerve trunk

Babuci, Angela; Zorina, Zinovia; Bendelic, Anastasia; Ostahi, Nadia; Botnari, Tatiana; Botnaru, Doina; Lehtman, Sofia; Motelica, Gabriela; Nastas, Liliana; Calancea, Sergiu (CEP Medicina, 2025)

Introduction: The facial nerve trunk (FNT) is vulnerable to iatrogenic injures in surgery of the retromandibular region, particularly in mastoidectomy. Variation of the FNT number, topography and course increase the risk ...
Current events in liver transplatology

Zavtoni, Ana-Maria; Harea, Gheorghe (CEP Medicina, 2025)

Background. Liver transplantation is a surgical procedure that involves removing a diseased liver and replacing it with a healthy liver from another person, called a donor. This procedure is used when the liver is unable ...

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„Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025: Recent submissions

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