Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025 by Issue Date

Browsing „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025 by Issue Date

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  • Cardiorenal syndrome and cellular therapeutic perspectives: risk factor identification for targeted interventions 
    Tonofa, Maria; Purteanu, Lilia; Benescu, Irina; Cozma, Octavian; Grib, Livi (CEP Medicina, 2025)
    Introduction. Cardiorenal syndrome (CRS) is a complex pathological condition that highlights the bidirectional relationship between heart failure and chronic kidney disease. This interdependence is driven by multiple ...
  • Specific features of the facial nerve trunk 
    Babuci, Angela; Zorina, Zinovia; Bendelic, Anastasia; Ostahi, Nadia; Botnari, Tatiana; Botnaru, Doina; Lehtman, Sofia; Motelica, Gabriela; Nastas, Liliana; Calancea, Sergiu (CEP Medicina, 2025)
    Introduction: The facial nerve trunk (FNT) is vulnerable to iatrogenic injures in surgery of the retromandibular region, particularly in mastoidectomy. Variation of the FNT number, topography and course increase the risk ...
  • Exploring the impact of mesenchymal stem cells on chronic wound repair 
    Țarălungă, Maxim; Nacu, Viorel; Țarălungă, Tatiana; Bour, Alin (CEP Medicina, 2025)
    Introduction: Chronic wounds are a significant medical concern, especially among the aging population, with conditions like diabetic ulcers, and venous leg ulcers being prominent examples. These wounds often fail to heal ...
  • Stem cells in regenerative dentistry: actualities and future directions 
    Țurcan, Paula; Capcelea, Svetlana (CEP Medicina, 2025)
    Introduction. Stem cells are pluripotent cells capable of differentiating into various specialized cell types, making them a promising tool in regenerative dentistry. Their potential to regenerate different parts of the ...
  • Endocrine disruptors - a current problem for the human body 
    Zavtoni, Mariana; Miron, Inga; Bernic, Vladimir; Corețchi, Roman (CEP Medicina, 2025)
    Introduction. Endocrine disruptors are chemical substances that cause adverse effects in an organism or its offspring, leading to morphological and physiological changes and contributing to the deterioration of functional ...
  • Review of rodent hypertension glaucoma models 
    Țarălungă, Tatiana; Iacubițchii, Maria; Paduca, Ala; Nacu, Viorel (CEP Medicina, 2025)
    Background: Hypertension is a major risk factor for glaucoma, a leading cause of irreversible blindness. Elevated intraocular pressure (IOP) is central to glaucoma pathology, often causing optic nerve damage and retinal ...
  • Current events in liver transplatology 
    Zavtoni, Ana-Maria; Harea, Gheorghe (CEP Medicina, 2025)
    Background. Liver transplantation is a surgical procedure that involves removing a diseased liver and replacing it with a healthy liver from another person, called a donor. This procedure is used when the liver is unable ...
  • The role of glycation processes in aging 
    Ghinda, Daniela; Sardari, Veronica (CEP Medicina, 2025)
    Background. Glycation is a non-enzymatic reaction in which reducing sugars react with free amino groups in proteins, lipids, or nucleic acids, leading to the formation of advanced glycation end products (AGEs). AGE ...
  • Review of literature on combined liver elastography techniques 
    Calistru, Natalia; Țarălungă, Tatiana; Harti, Aliona (CEP Medicina, 2025)
    Background. Liver elastography has become a pivotal non-invasive method for assessing liver fibrosis, offering an alternative to traditional biopsy. Techniques such as transient elastography (TE), point shear wave ...
  • Tissue and cells transplantation in the Republic of Moldova, trendlines 
    Nacu, Viorel; Stepa, Serghei; Coșpormac, Igor; Cociug, Adrian; Cobzac, Vitalie; Guțu-Bahov, Cornelia; Tambalari, Tatiana (CEP Medicina, 2025)
    The development of tissue transplantation in the Republic of Moldova began in the 1960s with the use of bone grafts. This laid the foundation for the establishment of national infrastructure for tissue preservation and ...
  • Challenges in the use of glucocorticoids in transplantology 
    Guțu, Ina; Bacinschi, Nicolae; Țurcan, Lucia; Caracas, Anastasia; Mihalachi-Anghel, Maria (CEP Medicina, 2025)
    Introduction. Glucocorticoids (GCs) have long time played a key role in solid organ transplantation (SOT), thanks to their strong anti-inflammatory and immunosuppressive effects. However, their use presents a significant ...
  • The role of glycation on transplantology methods in cancer treatment 
    Grusac, Evgheni; Tagadiuc, Olga; Munteanu, Roman; Pantea, Valeriana; Sardari, Veronica (CEP Medicina, 2025)
    Background. Advanced glication end products (AGEs) are formed in result of Millard reaction in hiperglycemic conditions caused by Warburg`s effect. Many studies have shown the presence of AGEs in neoplastic tissues through ...
  • Exploring trabecular meshwork stem cells: potential roles, therapeutic implications and challenges in glaucoma 
    Iacubițchii, Maria; Bendelic, Eugeniu; Țarălungă, Tatiana; Nacu, Viorel (CEP Medicina, 2025)
    Introduction: Recent investigations surrounding trabecular mesh (TM) stem cells have generated significant interest due to their possible role in glaucoma treatment. Trabecular mesh cells are crucial in maintaining IOP ...
  • Biomaterials and nanotechnology in dental osseointegration 
    Babuci, Angela; Paz, Eli; Zorina, Zinovia; Stratulat, Silvia; Lehtman, Sofia; Calancea, Sergiu (CEP Medicina, 2025)
    Introduction: The osseointegration is a process of bone ingrowth into the surface of a load-carrying implant. Due to its low elastic modulus, excellent biocompatibility and resistance to corrosion, titanium is the most ...
  • Stem cell transplantation in infertility treatment: new perspectives in regenerative medicine 
    Ivanova, Svetlana; Foca, Ecaterina (CEP Medicina, 2025)
    Background. Female infertility is a multifactorial condition caused by factors such as ovarian dysfunction, endometrial disorders, hormonal imbalances, and age-related decline in reproductive potential. Stem cell ...
  • Cellular therapy with growth factors: a promising neuroregenerative approach in cerebral palsy 
    Iachimovschi, Dumitrița; Stratu, Ecaterina; Catcov, Carolina (CEP Medicina, 2025)
    Introduction: Cerebral palsy is a non-progressive condition caused by a series of neurological disorders that occur during fetal brain development, either before or after birth. It represents a major global issue that ...
  • Agent-based modeling of fluid dynamics in lung tissue engineering 
    Iapăscurtă, Victor (CEP Medicina, 2025)
    Introduction: In tissue engineering for lung applications, understanding and controlling fluid dynamics within engineered constructs is paramount. Agent-based modeling (ABM) offers a powerful framework to simulate complex ...
  • Liver transplantation for hepatocellular carcinoma 
    Hotineanu, Adriana; Burgoci, Sergiu (CEP Medicina, 2025)
    Introduction. Hepatocellular carcinoma is one of the most frequent complications of advanced liver cirrhosis, associated with high mortality. Liver transplantation is an effective therapeutic solution in selected cases, ...
  • The effect of stimulating local immunity with autologous cells in the treatment of tissue inflammatory process on the body’s resistance to infection 
    Danilov, Lucian; Maniuc, Mihail; David, Valeriu; Ababii, Polina; Bugan, Maria; Furculița, Daniel; Nacu, Viorel (CEP Medicina, 2025)
    Introduction. The application of autologous mononuclear cells to the area of inflammatory affected tissue produces the stimulation of certain cytokines with anti-inflammatory properties, the proliferation of cells involved ...
  • Human tissue donation and transplantation in the Republic of Moldova 
    Buga, Diana; Țîmbalari, Tatiana; Romanciuc, Grigore; Ciubotaru, Ludmila; Visterniceanu, Dorian; Cornea, Cornelia; Fărîma, Marc; Ungureanu, Alina; Nacu, Viorel (CEP "Medicina", 2025)
    Introduction: In recent years, human tissue transplantation has gained increasing importance in modern medicine, expanding both in scope and medical applications. Advances in surgical techniques, improvements in tissue ...

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