Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025 by Issue Date

Browsing „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025 by Issue Date

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  • Neuroprotective effects of ethanolic extracts from Solanum macrocarpon in a zebrafish model of scopolamine-induced Alzheimer's disease-related dementia 
    Brînza, Ion; Guliev, Corina A.; Oluwabukola Oresanya, Ibukun; Nazli Gok, Hasya; Erdogan Orhan, Ilkay; Hrițcu, Lucian (CEP Medicina, 2025)
    Introduction. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and oxidative stress. Natural bioactive compounds with antioxidant and neuroprotective properties have ...
  • Correlation between CD45 expression and clinical-pathological variables in invasive ductal breast carcinoma associated with type 2 diabetes mellitus 
    Brînza, Dumitru (CEP Medicina, 2025)
    Introduction. This study investigates the correlation between CD45 expression and clinicalpathological variables in invasive ductal breast carcinoma associated with type 2 diabetes mellitus. CD45, an immune regulator, was ...
  • Cardiorenal syndrome and cellular therapeutic perspectives: risk factor identification for targeted interventions 
    Tonofa, Maria; Purteanu, Lilia; Benescu, Irina; Cozma, Octavian; Grib, Livi (CEP Medicina, 2025)
    Introduction. Cardiorenal syndrome (CRS) is a complex pathological condition that highlights the bidirectional relationship between heart failure and chronic kidney disease. This interdependence is driven by multiple ...
  • Specific features of the facial nerve trunk 
    Babuci, Angela; Zorina, Zinovia; Bendelic, Anastasia; Ostahi, Nadia; Botnari, Tatiana; Botnaru, Doina; Lehtman, Sofia; Motelica, Gabriela; Nastas, Liliana; Calancea, Sergiu (CEP Medicina, 2025)
    Introduction: The facial nerve trunk (FNT) is vulnerable to iatrogenic injures in surgery of the retromandibular region, particularly in mastoidectomy. Variation of the FNT number, topography and course increase the risk ...
  • Stem cells in regenerative dentistry: actualities and future directions 
    Țurcan, Paula; Capcelea, Svetlana (CEP Medicina, 2025)
    Introduction. Stem cells are pluripotent cells capable of differentiating into various specialized cell types, making them a promising tool in regenerative dentistry. Their potential to regenerate different parts of the ...
  • Endocrine disruptors - a current problem for the human body 
    Zavtoni, Mariana; Miron, Inga; Bernic, Vladimir; Corețchi, Roman (CEP Medicina, 2025)
    Introduction. Endocrine disruptors are chemical substances that cause adverse effects in an organism or its offspring, leading to morphological and physiological changes and contributing to the deterioration of functional ...
  • Variability of the paired visceral branches of the abdominal aorta 
    Botnari, Tatiana; Babuci, Angela; Zorina, Zinovia; Catereniuc, Ilia; Botnaru, Doina; Ostahi, Nadia (CEP Medicina, 2025)
    Introduction: The demand for an individualized approach in interventional surgery of abdominal cavity organs has recently increased. Due to various surgical techniques and large number of surgeries, including kidney ...
  • Anatomical variability of the deep femoral artery 
    Botnaru, Doina; Zorina, Zinovia; Babuci, Angela; Catereniuc, Ilia; Botnari, Tatiana (CEP Medicina, 2025)
    Introduction: The deep femoral artery (DFA) serves as a crucial „turning point” between collateral circulation of the pelvis and that of the lower limb (LL), playing a determinant role not only in femoropopliteal axis ...
  • Current events in liver transplatology 
    Zavtoni, Ana-Maria; Harea, Gheorghe (CEP Medicina, 2025)
    Background. Liver transplantation is a surgical procedure that involves removing a diseased liver and replacing it with a healthy liver from another person, called a donor. This procedure is used when the liver is unable ...
  • Stem cell transplantation in bipolar disorder: exploring regenerative treatment approaches 
    Sîrbu, Mariana; Bologan, Alina (CEP Medicina, 2025)
    Introduction: Bipolar disorder (BD) is a chronic neuropsychiatric condition affecting over 1% of the global population, characterized by alternating episodes of mania and depression. Traditional pharmacological treatments, ...
  • Exploring the impact of mesenchymal stem cells on chronic wound repair 
    Țarălungă, Maxim; Nacu, Viorel; Țarălungă, Tatiana; Bour, Alin (CEP Medicina, 2025)
    Introduction: Chronic wounds are a significant medical concern, especially among the aging population, with conditions like diabetic ulcers, and venous leg ulcers being prominent examples. These wounds often fail to heal ...
  • Adipose tissue in chest region and its impact on the condition of various organs 
    Hacina, Tamara; Darwich, Jasmin (CEP Medicina, 2025)
    Introduction. The presence of the adipose tissue in the chest region might be linked to many pathological conditions meanwhile it can be physiological in many cases. A comprehensive assessment requires a morphological ...
  • Review of rodent hypertension glaucoma models 
    Țarălungă, Tatiana; Iacubițchii, Maria; Paduca, Ala; Nacu, Viorel (CEP Medicina, 2025)
    Background: Hypertension is a major risk factor for glaucoma, a leading cause of irreversible blindness. Elevated intraocular pressure (IOP) is central to glaucoma pathology, often causing optic nerve damage and retinal ...
  • Liver transplantation from a living-donor 
    Stoian, Carolina (CEP Medicina, 2025)
    Introduction. Living-donor liver transplantation (LDLT) is vital for end-stage liver disease and acute liver failure, alleviating organ shortages and reducing wait times. In the Republic of Moldova, where deceased-donor ...
  • Liver transplantation in Wilson’s disease 
    Rotaru, Ludmila (CEP Medicina, 2025)
    Background. Wilson’s disease is a rare genetic disorder caused by excessive copper accumulation in the body, particularly in the liver and brain. In severe cases, where the disease leads to liver failure, liver transplantation ...
  • The influence of calcitriol on the Warburg efect in cancer 
    Cojoc, Daniela; Sardari, Veronica; Munteanu, Roman; Stratulat, Silvia; Pantea, Valeriana; Tagadiuc, Olga (CEP Medicina, 2025)
    Background. Cancer cells undergo changes in the tumorigenic process through the Warburg effect, also known as aerobic gligolysis. The Warburg effect ensures the conversion of glucose to pyruvate and subsequently to lactate ...
  • The role of vitamin D in the Wnt/β-catenin signaling pathway 
    Cojoc, Daniela; Sardari, Veronica (CEP Medicina, 2025)
    Background. The Wnt/β-catenin signaling pathway is a complex system involved in immune homeostasis, tissue regeneration, and various physiological processes. Aberrant activation of the signaling pathway, driven by genetic ...
  • LUCAs testimonies: cell evolution 
    Cotelea-Baligari, Ana; Șaptefrați, Lilian (CEP Medicina, 2025)
    Introduction. The last universal common ancestor (LUCA) represents a pivotal stage in cell evolution, serving not only as the bridge between prebiotic chemistry and modern biological systems but also providing insights ...
  • Why is “brainwashing” necessary? Histophysiology investigation 
    Crețu, Maxim; Șaptefrați, Lilian (CEP Medicina, 2025)
    Background. The glymphatic system represents the indispensable mechanism for maintaining cerebral homeostasis, facilitating the drainage of cerebrospinal fluid (CSF) and the direct evacuation of neurotoxic metabolites. ...
  • The influence of vitamin D on metabolic syndrome 
    Condrea, Daniela; Protopop, Svetlana (CEP Medicina, 2025)
    Introduction. Metabolic syndrome (MS) is a major public health concern, characterized by a combination of central obesity, dyslipidemia, hypertension, and insulin resistance. In recent years, increasing evidence has ...

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