Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025 by Issue Date

Browsing „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025 by Issue Date

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  • The influence of calcitriol on the Warburg efect in cancer 
    Cojoc, Daniela; Sardari, Veronica; Munteanu, Roman; Stratulat, Silvia; Pantea, Valeriana; Tagadiuc, Olga (CEP Medicina, 2025)
    Background. Cancer cells undergo changes in the tumorigenic process through the Warburg effect, also known as aerobic gligolysis. The Warburg effect ensures the conversion of glucose to pyruvate and subsequently to lactate ...
  • The role of vitamin D in the Wnt/β-catenin signaling pathway 
    Cojoc, Daniela; Sardari, Veronica (CEP Medicina, 2025)
    Background. The Wnt/β-catenin signaling pathway is a complex system involved in immune homeostasis, tissue regeneration, and various physiological processes. Aberrant activation of the signaling pathway, driven by genetic ...
  • LUCAs testimonies: cell evolution 
    Cotelea-Baligari, Ana; Șaptefrați, Lilian (CEP Medicina, 2025)
    Introduction. The last universal common ancestor (LUCA) represents a pivotal stage in cell evolution, serving not only as the bridge between prebiotic chemistry and modern biological systems but also providing insights ...
  • Why is “brainwashing” necessary? Histophysiology investigation 
    Crețu, Maxim; Șaptefrați, Lilian (CEP Medicina, 2025)
    Background. The glymphatic system represents the indispensable mechanism for maintaining cerebral homeostasis, facilitating the drainage of cerebrospinal fluid (CSF) and the direct evacuation of neurotoxic metabolites. ...
  • The influence of vitamin D on metabolic syndrome 
    Condrea, Daniela; Protopop, Svetlana (CEP Medicina, 2025)
    Introduction. Metabolic syndrome (MS) is a major public health concern, characterized by a combination of central obesity, dyslipidemia, hypertension, and insulin resistance. In recent years, increasing evidence has ...
  • Q-SPECT CT in the assesment of post-pulmonary embolism complications: a new perspective on risk stratification and management 
    Ivanes, Igor; Sorici, Galina; Cîvîrjîc, Irina; Diaconu, Nadejda; Grosu, Aurel; Gorohova, Marina; Ivanes, Anastasia; Plugaru, Ana; Ambroci, Rada; Cărăuș, Victoria; Lupu, Diana; Rusanovschi-Balica, Olga; Surev, Artiom (CEP Medicina, 2025)
    Introduction. Pulmonary embolism (PE) is a severe cardiovascular condition associated with significant morbidity, often resulting in long-term complications despite adequate anticoagulation. Chronic thromboembolic pulmonary ...
  • The role of glycation processes in aging 
    Ghinda, Daniela; Sardari, Veronica (CEP Medicina, 2025)
    Background. Glycation is a non-enzymatic reaction in which reducing sugars react with free amino groups in proteins, lipids, or nucleic acids, leading to the formation of advanced glycation end products (AGEs). AGE ...
  • Fecal microbiota transplantation in cirrhosis: a microbiome-based therapeutic revolution 
    Marcu, Beatrice; Sardari, Veronica (CEP Medicina, 2025)
    Introduction. The gut microbiota, as well as the gut-liver axis, play a significantly important role in the fibrosis process. As fibrosis progresses to cirrhosis, it further worsens the microbiota, creating a vicious cycle ...
  • Human tissue donation and transplantation in the Republic of Moldova 
    Buga, Diana; Țîmbalari, Tatiana; Romanciuc, Grigore; Ciubotaru, Ludmila; Visterniceanu, Dorian; Cornea, Cornelia; Fărîma, Marc; Ungureanu, Alina; Nacu, Viorel (CEP "Medicina", 2025)
    Introduction: In recent years, human tissue transplantation has gained increasing importance in modern medicine, expanding both in scope and medical applications. Advances in surgical techniques, improvements in tissue ...
  • Regarding corneal preparation in the human tissue bank of the Republic of Moldova, during 11 years of activity 
    Cociug, Adrian; Macagonova, Olga; Dumbrăveanu, Lilia; Cușnir, Valeriu; Nacu, Viorel (CEP Medicina, 2025)
    Introduction. The cornea is the tissue of the human eye that improves the quality of the image formed on the retina. The quality of corneal tissue can be influenced by several factors inherent to the recipient, the donor, ...
  • Vestibular migraine. Pathogenesis, differential diagnosis, treatment method 
    Zemleanschih, Ecaterina; Istrati, Nina (CEP Medicina, 2025)
    Introduction. Vestibular migraine (VM) is probably the second most common cause of dizziness, affecting approximately 3% of population. In recent years, the appearance of new studies aiming to understanding the pathophysiology ...
  • Chronic pelvic pain syndrome in neurological practice. Etiology, differential diagnosis and treatment 
    Rudencu, Alina; Istrati, Nina (CEP Medicina, 2025)
    Introduction. Chronic pelvic pain is an interdisciplinary problem that affects not only the neurological field but also the gynecological and surgical fields. It is estimated that between 5-26% of women and 2-10% of men ...
  • The implications of autophagy in Crohn’s disease 
    Țarălungă, Constantin; Munteanu, Roman; Repciuc, Ana; Sardari, Veronica (CEP Medicina, 2025)
    Introduction: Inflammatory bowel disease comprises a variety of chronic inflammatory disorders, that affect the gastrointestinal tract, the most common ones being ulcerative colitis and Crohn's disease, that, if left ...
  • The role of pericytes in modulating ophthalmic diseases: a review of current insights and therapeutic perspectives 
    Pavlovschi, Ecaterina; Tagadiuc, Olga (CEP Medicina, 2025)
    Introduction. Pericytes have an important role in preserving the blood vessels in the retina by keeping them stable and ensuring proper functioning of the endothelial cells. Meanwhile they also preserve the integrity of ...
  • Obesity in postmenopausal osteoporosis 
    Repciuc, Ana; Țarălungă, Constantin; Sardari, Veronica (CEP Medicina, 2025)
    Introduction. Obesity is a chronic disease that is closely correlated with bone mineral density (BMD), resulting in contradictory effects. The aim of this study is to assess the potential risks in overweight individuals ...
  • Bone graft use in internal fixation of proximal and diaphyseal humeral fractures and pseudoarthrosis 
    Cojocari, Ștefan; Cobzac, Vitalie; Nacu, Viorel; Cociug, Adrian; Buzu, Dumitru; Vacarciuc, Ion; Țîcu, Ion; Guțu, Andrian; Suveică, Teodor; Frasineac, Victor; Caproș, Nicolae; Taran, Anatolie (CEP Medicina, 2025)
    Introduction: This study explores the use of bone graft in combination with internal fixation for treating fractures and pseudarthrosis of the proximal and diaphyseal humerus. Materials and Methods: We retrospectively ...
  • Analysis of contemporary trends in morphometry 
    Petreanu, Carina; Șaptefrați, Lilian (CEP Medicina, 2025)
    Background: Morphometry plays a crucial role in modern histology, allowing for the quantitative analysis of the morphological parameters of cells and tissues. With the advancement of digital technologies and machine ...
  • Effects of vitamin D supplements on patients with hypothyroidism 
    Rabbi, Syeda; Catcov, Carolina (CEP Medicina, 2025)
    Introduction: Hypothyroidism is a common endocrine disorder, ranging from 0.1% to 12.5%; women are more likely to develop the condition. The causes can be multiple, but most often 20-30% of cases are of autoimmune origin. ...
  • Use of cell transplants in jaw reconstructive surgeries 
    Rusu-Radzichevici, Natalia; Radzichevici, Mihail; Ștefaneț, Veronica (CEP Medicina, 2025)
    Introduction: During th eyears 2006-2024, a lot of 190 patients were studied, all of which underwent treatment in the department of oral and maxillofacial surgery, for jaw bone necrosis, caused by drug use, bisphosphonates ...
  • Tissue and cells transplantation in the Republic of Moldova, trendlines 
    Nacu, Viorel; Stepa, Serghei; Coșpormac, Igor; Cociug, Adrian; Cobzac, Vitalie; Guțu-Bahov, Cornelia; Tambalari, Tatiana (CEP Medicina, 2025)
    The development of tissue transplantation in the Republic of Moldova began in the 1960s with the use of bone grafts. This laid the foundation for the establishment of national infrastructure for tissue preservation and ...

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