Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing The Materials of the National Scientific Conference with International Participation „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025: [Abstracts] by Issue Date

Browsing The Materials of the National Scientific Conference with International Participation „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025: [Abstracts] by Issue Date

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  • The influence of calcitriol on the Warburg efect in cancer 
    Cojoc, Daniela; Sardari, Veronica; Munteanu, Roman; Stratulat, Silvia; Pantea, Valeriana; Tagadiuc, Olga (CEP Medicina, 2025)
    Background. Cancer cells undergo changes in the tumorigenic process through the Warburg effect, also known as aerobic gligolysis. The Warburg effect ensures the conversion of glucose to pyruvate and subsequently to lactate ...
  • The role of vitamin D in the Wnt/β-catenin signaling pathway 
    Cojoc, Daniela; Sardari, Veronica (CEP Medicina, 2025)
    Background. The Wnt/β-catenin signaling pathway is a complex system involved in immune homeostasis, tissue regeneration, and various physiological processes. Aberrant activation of the signaling pathway, driven by genetic ...
  • LUCAs testimonies: cell evolution 
    Cotelea-Baligari, Ana; Șaptefrați, Lilian (CEP Medicina, 2025)
    Introduction. The last universal common ancestor (LUCA) represents a pivotal stage in cell evolution, serving not only as the bridge between prebiotic chemistry and modern biological systems but also providing insights ...
  • Why is “brainwashing” necessary? Histophysiology investigation 
    Crețu, Maxim; Șaptefrați, Lilian (CEP Medicina, 2025)
    Background. The glymphatic system represents the indispensable mechanism for maintaining cerebral homeostasis, facilitating the drainage of cerebrospinal fluid (CSF) and the direct evacuation of neurotoxic metabolites. ...
  • Adipose tissue in chest region and its impact on the condition of various organs 
    Hacina, Tamara; Darwich, Jasmin (CEP Medicina, 2025)
    Introduction. The presence of the adipose tissue in the chest region might be linked to many pathological conditions meanwhile it can be physiological in many cases. A comprehensive assessment requires a morphological ...
  • Liver transplantation in Wilson’s disease 
    Rotaru, Ludmila (CEP Medicina, 2025)
    Background. Wilson’s disease is a rare genetic disorder caused by excessive copper accumulation in the body, particularly in the liver and brain. In severe cases, where the disease leads to liver failure, liver transplantation ...
  • The influence of vitamin D on metabolic syndrome 
    Condrea, Daniela; Protopop, Svetlana (CEP Medicina, 2025)
    Introduction. Metabolic syndrome (MS) is a major public health concern, characterized by a combination of central obesity, dyslipidemia, hypertension, and insulin resistance. In recent years, increasing evidence has ...
  • The role of endothelins in cancer progression: recent insights and therapeutic opportunities 
    Cazacu, Felicia; Sardari, Veronica; Munteanu, Roman; Rudic, Ciprian; Tagadiuc, Olga (CEP Medicina, 2025)
    Background. Endothelins (ETs) and their receptors (ETAR and ETBR) play a significant role in cancer progression, influencing processes such as proliferation, invasion, and metastasis. The endothelin axis contributes to ...
  • Correlations between echocardiographic findings and SPECT CT as a predective tool for chronic thromboembolic pulmonary hypertension in post-pulmonary embolism patients 
    Sorici, Galina; Diaconu, Nadejda; Civirjic, Irina; Ivanes, Igor; Gorohova, Marina; Plugaru, Ana; Grosu, Aurel (CEP Medicina, 2025)
    Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe but potentially treatable complication of pulmonary embolism (PE). SPECT CT has emerged as a non-invasive modality capable of detecting residual ...
  • Telomere shortening as a mechanism for the induction of neurodegenetative diseases 
    Casian, Andreea; Sardari, Veronica; Stratulat, Silvia; Munteanu, Roman; Cojoc, Daniela; Tagadiuc, Olga (CEP Medicina, 2025)
    Background. Telomeres are considered the "cellular biological clock" because their length could determine the possible number of cell divisions. Telomerase plays a role in maintaining telomere length. Telomerase ensures ...
  • Molecular mechanisms of neuronal aging and neurodegeneration 
    Demidova, Inga; Șaptefrați, Lilian (CEP Medicina, 2025)
    Background. Aging of the nervous system is accompanied by complex molecular changes that contribute to the development of neurodegenerative diseases. Understanding these mechanisms is crucial for developing effective ...
  • Mitochondrial calcium regulation in Alzheimer`s disease 
    Casian, Andreea; Sardari, Veronica (CEP Medicina, 2025)
    Background. Calcium ions (Ca²⁺) play an essential role in neuronal function, contributing to synaptic transmission, interneuronal communication, and neuroglial interactions. Mitochondria regulate the intracellular ...
  • Q-SPECT CT in the assesment of post-pulmonary embolism complications: a new perspective on risk stratification and management 
    Ivanes, Igor; Sorici, Galina; Cîvîrjîc, Irina; Diaconu, Nadejda; Grosu, Aurel; Gorohova, Marina; Ivanes, Anastasia; Plugaru, Ana; Ambroci, Rada; Cărăuș, Victoria; Lupu, Diana; Rusanovschi-Balica, Olga; Surev, Artiom (CEP Medicina, 2025)
    Introduction. Pulmonary embolism (PE) is a severe cardiovascular condition associated with significant morbidity, often resulting in long-term complications despite adequate anticoagulation. Chronic thromboembolic pulmonary ...
  • Fecal microbiota transplantation in cirrhosis: a microbiome-based therapeutic revolution 
    Marcu, Beatrice; Sardari, Veronica (CEP Medicina, 2025)
    Introduction. The gut microbiota, as well as the gut-liver axis, play a significantly important role in the fibrosis process. As fibrosis progresses to cirrhosis, it further worsens the microbiota, creating a vicious cycle ...
  • Neuroprotective effects of ethanolic extracts from Solanum macrocarpon in a zebrafish model of scopolamine-induced Alzheimer's disease-related dementia 
    Brînza, Ion; Guliev, Corina A.; Oluwabukola Oresanya, Ibukun; Nazli Gok, Hasya; Erdogan Orhan, Ilkay; Hrițcu, Lucian (CEP Medicina, 2025)
    Introduction. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and oxidative stress. Natural bioactive compounds with antioxidant and neuroprotective properties have ...
  • Correlation between CD45 expression and clinical-pathological variables in invasive ductal breast carcinoma associated with type 2 diabetes mellitus 
    Brînza, Dumitru (CEP Medicina, 2025)
    Introduction. This study investigates the correlation between CD45 expression and clinicalpathological variables in invasive ductal breast carcinoma associated with type 2 diabetes mellitus. CD45, an immune regulator, was ...
  • Specific features of the facial nerve trunk 
    Babuci, Angela; Zorina, Zinovia; Bendelic, Anastasia; Ostahi, Nadia; Botnari, Tatiana; Botnaru, Doina; Lehtman, Sofia; Motelica, Gabriela; Nastas, Liliana; Calancea, Sergiu (CEP Medicina, 2025)
    Introduction: The facial nerve trunk (FNT) is vulnerable to iatrogenic injures in surgery of the retromandibular region, particularly in mastoidectomy. Variation of the FNT number, topography and course increase the risk ...
  • Nasal permeability in inflammatory rhinosinusal diseases in children 
    Maniuc, Mihail; Danilov, Lucian; Ababii, Polina; Nacu, Viorel; Furculița, Daniel; Bugan, Maria; Crețu, Carolina; Vishnumaya, Sureshan (CEP Medicina, 2025)
    Introduction: Rhinosinusal inflammatory diseases constitute a current problem of contemporary rhinology. Rhinitis, sinusitis seriously affect the physiological functions of the nose, including the most important of them, ...
  • Endocrine disruptors - a current problem for the human body 
    Zavtoni, Mariana; Miron, Inga; Bernic, Vladimir; Corețchi, Roman (CEP Medicina, 2025)
    Introduction. Endocrine disruptors are chemical substances that cause adverse effects in an organism or its offspring, leading to morphological and physiological changes and contributing to the deterioration of functional ...
  • Variability of the paired visceral branches of the abdominal aorta 
    Botnari, Tatiana; Babuci, Angela; Zorina, Zinovia; Catereniuc, Ilia; Botnaru, Doina; Ostahi, Nadia (CEP Medicina, 2025)
    Introduction: The demand for an individualized approach in interventional surgery of abdominal cavity organs has recently increased. Due to various surgical techniques and large number of surgeries, including kidney ...

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