Abstract:
Background.
Anomalies of development of the reproductive system are combined with defects of organs of the urinary system.
Depending on the stage of intrauterine development at which the embryo is affected by the teratogenic factor or
genetic features, various abnormalities of the female reproductive and urinary system are formed.
Material and methods
The medical histories of 29 patients from the archive of the State Scientific Research Center “Mother and Child”
aged 11 to 38 years with congenital anomalies of the genital organs, who were admitted from 2017 to 2024, were
retrospectively studied. Statistical processing and calculation of the Spearman correlation criterion were carried out
using Microsoft Excel for Microsoft 365 MSO and an online calculator medstatistic.ru.
Results
The result of the calculation of the Spearman correlation criterion (p) was the identification of a link (p=0.950,
p<0.05) between the agenesis of one of the kidneys and the presence in patients of uterine doubling without or with
a vaginal septum/cervical atresia.
In patients with a vaginal septum, agenesis of the left kidney is associated with obstruction of the left uterus, and
agenesis of the right kidney is associated with obstruction of the right uterus.
Conclusions
It was found that the cause of congenital anomalies of the female reproductive system is the abnormal development,
fusion or absence of the Muller ducts during embryogenesis. A correlation was found (p=0.950, p<0.05) between
renal agenesis and uterine doubling.
