Medicina internă în tranziţie de la medicina bazată pe dovezi la medicina personalizată: Congresul aniversar „80 de ani de inovaţie în sănătate şi educaţie medicală”, 20-22 octombrie 2025: Culegere de rezumate: Recent submissions

  • Management of infective endocarditis in the immunocompromised patient 
    Harghel, Inga; Grib, Livi; Grăjdieru, Romeo; Carauș, Victoria; Perveneț, Cristina; Fiodorova, Natalia; Samohvalov, Elena (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) represents a major public health challenge. The incidence of IE is 13.8 cases per 100,000 population, causing 66,300 deaths globally each year. Among immunocompromised patients, ...
  • Coronary artery dominance may predict future risk of atrial fibrillation 
    Grinevici, Pavel; Grejdieru, Alexandra; Catereniuc, Ilia; Samhvalov, Elena; Avramova, Tatiana; Grinevici, Irina; Grib, Livi (CEP Medicina, 2026)
    Introduction. Most patients have a right-dominant vascularization of the heart 85%, and 8% have left-dominant vascularization and 7% demonstrate variation of codominant. The population with left-dominant circulation is ...
  • The role of ferinject in the management of anemia in cardiorenal syndrome 
    Colnic, Diana; Perveneț, Cristina; Purteanu, Lilia; Carauș, Victoria; Jugurt, Victoria; Grib, Livi (CEP Medicina, 2026)
    Introduction. Cardiorenal syndrome (CRS) includes a spectrum of renal and cardiac disabilities, where loss of function of one organ contributes to diminished function of the other. Cardiorenal syndrome is frequently ...
  • Frederick syndrome associated with beta-blocker overdosage, clinical case 
    Cojocari, Doina; Samohvalov, Elena; Carauș, Victoria; Saracuța, Ala; Stepan, Ion; Lupu, Diana; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Frederick syndrome is a rare entity characterized by atrial fibrillation (AF) associated with complete atrioventricular (AV) block. Incidence consisting of 1-2 cases per 100,000 people/year, predominantly in ...
  • Ascending aortic aneurysm with severe valvular insufficiency and atypical onset with epigastric pain, case report 
    Ciobanu, Maria; Samohvalov, Elena; Banciu, Vera; Mileșco, Lenuța; Avram, Svetlana; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Ascending aortic aneurysm remains a severe condition with high risk of dissection or rupture. Atypical clinical presentation may delay diagnosis. Objective(s) of the study. To present a case of ascending ...
  • Chronic silent coronary syndrome – diagnostic features 
    Carauş, Victoria; Filimon, Silvia; Grib, Andrei; Lutîca, Nicolae; Samohvalov, Elena; Grejdieru, Alexandra; Grăjdieru, Romeo (CEP Medicina, 2026)
    Introduction. Chronic coronary syndrome (CCS) is a range of clinical manifestations or syndromes Resulting from structural and/or functional changes in the coronary arteries and/or microvascular system, often Resulting ...
  • Hypertensive emergency caused by severe carotid stenosis, clinical case 
    Avramova, Tatiana; Grib, Livi; Benesco, Irina; Samohvalov, Elena; Avenir, Anghelcev; Grinevici, Pavel; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Carotid stenosis is diagnosed in 25% of hypertensive patients, more commonly in men over 50 years of age. Interventional treatment facilitates the prognosis of patients. Hypertensive emergency and ineffective ...
  • Acute miocardial infarction in a patient with diabetes mellitus, clinical case 
    Anghelcev, Avenir; Avramova, Tatiana; Samohvalov, Elena; Grib, Livi; Grib, Andrei; Grăjdieru, Romeo; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Diabetes mellitus (DM) is a major cardiovascular risk factor associated with an increased incidence of acute ischemic events, including acute myocardial infarction (AMI). Chronic hyperglycemia contributes to ...
  • Left ventricular free wall rupture - the most severe complication of acute myocardial infarction 
    Nadejda, Albu; Tcaciuc, Angela; Carauș, Victoria; Damascan, Alexandru; Grib, Andrei (CEP Medicina, 2026)
    Introduction. Left ventricular free wall rupture is a mechanical complication that can occur on the 5th-14th day post-AMI with an incidence of 2-4% and a mortality of 20%. The most common rupture is the posterior ...
  • Empirical antimicrobian treatment of the patient with infectious endocarditis. Clinical case 
    Turcu, Corina; Istrati, Alina; Samohvalov, Elena; Panfile, Elena; Gaina, Valeria; Simon, Ana; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Infective endocarditis (IE) with negative blood cultures (BC) remains a severe pathology, with a high risk of mortality, caused by the progression of heart failure, embolic and neurological complications. ...
  • Echocardiographic features in diagnosing aortic stenosis 
    Stratu, Andreea; Samohvalov, Elena; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Aortic stenosis (AS) is a valvular condition that obstructs left ventricular outflow, commonly seen in the elderly and associated with increased morbidity and mortality. Echocardiography remains the standard ...
  • Infective endocarditis complicated by septic nephritis. Clinical case 
    Spatari, Xenia; Jacotă, Elena; Samohvalov, Elena; Spatari, Anastasia; Preguza, Victoria; Istrati, Alina; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) is a severe microbial disease that often occurs on the Background. of comorbidities and progresses with multi-organ complications, negatively impacting the disease prognosis. The ...
  • Infective endocarditis in a pacient with diabetes mellitus. Clinical case 
    Preguza, Victoria; Grăjdieru, Romeo; Samohvalov, Elena; Istrati, Alina; Spatari, Xenia; Jacotă, Elena; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) frequently develops in an immunocompromised patients with multiple comorbidities: diabetes mellitus (DM) (17–30%), hepatitis, liver cirrhosis, renal diseases, cancer, or AIDS. ...
  • Infective endocarditis with embolic syndrome. Clinical case 
    Istrati, Alina; Spatari, Xenia; Grib, Livi; Samohvalov, Elena; Jacotă, Elena; Gaina, Valeria; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) presents with systemic embolic complications in 10-57% of cases: cerebral (26.3%), splenic (6.8%), and pulmonary (6.1-32%), leading to a malignant course with disabilities (172,359 ...
  • Infective endocarditis with neurological complications. Clinical case 
    Gaina, Valeria; Jacotă, Elena; Samohvalov, Elena; Panfile, Elena; Turcu, Corina; Feodorovici, Evelina; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) is a serious infectious disease, with polyorganic complications, which causes a high risk of death (20-25%). In 20-40% of cases, IE is complicated by neurological disorders as: ...
  • Vascular damage in patients with diabetes mellitus and smoking 
    Dina, More; Angela, Tcaciuc; Tatiana, More (CEP Medicina, 2026)
    Background. Atherosclerosis is a progressive systemic disease associated with fatal cardiovascular (CV) complications. Diabetes mellitus (DM) and smoking are two major CV risk factors contributing to the onset of ...
  • The role of personalized medicine in redefining the clinical management of chronic obstructive pulmonary diseases (COPD) 
    Popovici, Daniela Georgeta; Lixandru-Dohotariu, Sorana; Lavinia, Carmen; Panait, Silvia; Scîntee, Gabriela; Vlădescu, Cristian; Ciutan, Marius (CEP Medicina, 2026)
    Background. For decades COPD has been managed uniformly based on pulmonary function parameters. Personalized medicine takes into account relevant phenotypes, endotypes, biomarkers, advanced imaging and comorbidities into ...
  • Glucose is not always the answer: a case of Auto-Brewery Syndrome 
    Țânț, Andrada; Reuț, Anca; Puriș, Cătălina-Maria; Țichindeleanu, Andra; Iancu, Bianca (CEP Medicina, 2026)
    Background. Auto-Brewery Syndrome (ABS) is a rare metabolic disorder characterized by the endogenous production of ethanol through the fermentation of ingested carbohydrates in the gastrointestinal tract, causing ...
  • miRNA expression in papillary thyroid carcinoma tissue 
    Manda, Dana; Nedelcu, Ioana; Botezatu, Anca; Ioachim, Dumitru; Oros, Sabina; Schipor, Sorina; Badiu, Corin (CEP Medicina, 2026)
    Background. MicroRNAs (miRNAs) play a crucial role in the development and progression of papillary thyroid cancer (PTC), the most common thyroid malignancy. They are small noncoding RNAs that regulate gene expression ...

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