Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing Medicina internă în tranziţie de la medicina bazată pe dovezi la medicina personalizată: Congresul aniversar „80 de ani de inovaţie în sănătate şi educaţie medicală”, 20-22 octombrie 2025: Culegere de rezumate by Issue Date

Browsing Medicina internă în tranziţie de la medicina bazată pe dovezi la medicina personalizată: Congresul aniversar „80 de ani de inovaţie în sănătate şi educaţie medicală”, 20-22 octombrie 2025: Culegere de rezumate by Issue Date

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  • miRNA expression in papillary thyroid carcinoma tissue 
    Manda, Dana; Nedelcu, Ioana; Botezatu, Anca; Ioachim, Dumitru; Oros, Sabina; Schipor, Sorina; Badiu, Corin (CEP Medicina, 2026)
    Background. MicroRNAs (miRNAs) play a crucial role in the development and progression of papillary thyroid cancer (PTC), the most common thyroid malignancy. They are small noncoding RNAs that regulate gene expression ...
  • Glucose is not always the answer: a case of Auto-Brewery Syndrome 
    Țânț, Andrada; Reuț, Anca; Puriș, Cătălina-Maria; Țichindeleanu, Andra; Iancu, Bianca (CEP Medicina, 2026)
    Background. Auto-Brewery Syndrome (ABS) is a rare metabolic disorder characterized by the endogenous production of ethanol through the fermentation of ingested carbohydrates in the gastrointestinal tract, causing ...
  • Infective endocarditis in a pacient with diabetes mellitus. Clinical case 
    Preguza, Victoria; Grăjdieru, Romeo; Samohvalov, Elena; Istrati, Alina; Spatari, Xenia; Jacotă, Elena; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) frequently develops in an immunocompromised patients with multiple comorbidities: diabetes mellitus (DM) (17–30%), hepatitis, liver cirrhosis, renal diseases, cancer, or AIDS. ...
  • Infective endocarditis complicated by septic nephritis. Clinical case 
    Spatari, Xenia; Jacotă, Elena; Samohvalov, Elena; Spatari, Anastasia; Preguza, Victoria; Istrati, Alina; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) is a severe microbial disease that often occurs on the Background. of comorbidities and progresses with multi-organ complications, negatively impacting the disease prognosis. The ...
  • Acute miocardial infarction in a patient with diabetes mellitus, clinical case 
    Anghelcev, Avenir; Avramova, Tatiana; Samohvalov, Elena; Grib, Livi; Grib, Andrei; Grăjdieru, Romeo; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Diabetes mellitus (DM) is a major cardiovascular risk factor associated with an increased incidence of acute ischemic events, including acute myocardial infarction (AMI). Chronic hyperglycemia contributes to ...
  • Empirical antimicrobian treatment of the patient with infectious endocarditis. Clinical case 
    Turcu, Corina; Istrati, Alina; Samohvalov, Elena; Panfile, Elena; Gaina, Valeria; Simon, Ana; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Infective endocarditis (IE) with negative blood cultures (BC) remains a severe pathology, with a high risk of mortality, caused by the progression of heart failure, embolic and neurological complications. ...
  • Chronic silent coronary syndrome – diagnostic features 
    Carauş, Victoria; Filimon, Silvia; Grib, Andrei; Lutîca, Nicolae; Samohvalov, Elena; Grejdieru, Alexandra; Grăjdieru, Romeo (CEP Medicina, 2026)
    Introduction. Chronic coronary syndrome (CCS) is a range of clinical manifestations or syndromes Resulting from structural and/or functional changes in the coronary arteries and/or microvascular system, often Resulting ...
  • Left ventricular free wall rupture - the most severe complication of acute myocardial infarction 
    Nadejda, Albu; Tcaciuc, Angela; Carauș, Victoria; Damascan, Alexandru; Grib, Andrei (CEP Medicina, 2026)
    Introduction. Left ventricular free wall rupture is a mechanical complication that can occur on the 5th-14th day post-AMI with an incidence of 2-4% and a mortality of 20%. The most common rupture is the posterior ...
  • Frederick syndrome associated with beta-blocker overdosage, clinical case 
    Cojocari, Doina; Samohvalov, Elena; Carauș, Victoria; Saracuța, Ala; Stepan, Ion; Lupu, Diana; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Frederick syndrome is a rare entity characterized by atrial fibrillation (AF) associated with complete atrioventricular (AV) block. Incidence consisting of 1-2 cases per 100,000 people/year, predominantly in ...
  • Ascending aortic aneurysm with severe valvular insufficiency and atypical onset with epigastric pain, case report 
    Ciobanu, Maria; Samohvalov, Elena; Banciu, Vera; Mileșco, Lenuța; Avram, Svetlana; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Ascending aortic aneurysm remains a severe condition with high risk of dissection or rupture. Atypical clinical presentation may delay diagnosis. Objective(s) of the study. To present a case of ascending ...
  • Hypertensive emergency caused by severe carotid stenosis, clinical case 
    Avramova, Tatiana; Grib, Livi; Benesco, Irina; Samohvalov, Elena; Avenir, Anghelcev; Grinevici, Pavel; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Carotid stenosis is diagnosed in 25% of hypertensive patients, more commonly in men over 50 years of age. Interventional treatment facilitates the prognosis of patients. Hypertensive emergency and ineffective ...
  • Echocardiographic features in diagnosing aortic stenosis 
    Stratu, Andreea; Samohvalov, Elena; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Aortic stenosis (AS) is a valvular condition that obstructs left ventricular outflow, commonly seen in the elderly and associated with increased morbidity and mortality. Echocardiography remains the standard ...
  • Drug-induced ventricular tachycardia in a patient with atrial flutter: a clinical case 
    Moroz, Serghei; Grib, Liviu; Grib, Andrei; Samohvalov, Elena; Stepan, Ion; Damașcan, Alexandru; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Atrial flutter (AFL) often persists in the absence of appropriate therapy and carries a high risk of thromboembolism. Flecainide, a class IC antiarrhythmic, is effective and safe in patients without structural ...
  • Type 2 diabetes alters local T-cell immune status in breast carcinoma 
    Brînză, Dumitru; Foca, Ecaterina; David, Valeriu; Fulga, Veaceslav (CEP Medicina, 2026)
    Background. Breast cancer and type 2 diabetes mellitus (T2DM) are prevalent chronic diseases that substantially affect health. T2DM can remodel the tumor microenvironment (TME) through several mechanisms. Yet the influence ...
  • Management of complicated infective endocarditis in the immunocompromised patient 
    Harghel, Inga; Grib, Liviu; Grăjdieru, Romeo; Carauș, Victoria; Perveneț, Cristina; Fiodorova, Natalia; Samohvalov, Elena (CEP Medicina, 2026)
    Background. Infective endocarditis represents a major public health challenge. The incidence of infective endocarditis is 13.8 cases per 100,000 population, causing 66,300 deaths annually worldwide. Among immunocompromised ...
  • Prevention of cardio-reno-metabolic syndrome in 2025 
    Purteanu, Lilia; Jugurt, Victoria; Benesco, Irina; Filimon, Silvia; Grib, Livi (CEP Medicina, 2026)
    Background. Cardiorenal-metabolic syndrome is the describtion of the health disorder attributable to the interconnection between obesity, diabetes, chronic kidney disease and cardiovascular diseases (CHD, AF, stroke, ...
  • Prevention of cardio-reno-metabolic syndrome in 2025 
    Purteanu, Lilia; Grib, Livi (CEP Medicina, 2026)
    Background. Cardiorenal-metabolic syndrome is the description of the health disorder attributable to the interconnection between obesity, diabetes, chronic kidney disease and cardiovascular diseases (CHD, AF, stroke, ...
  • Stretching methods used in the prevention of sports injuries 
    Hitova, Anastasia; Chihai, Victoria (CEP Medicina, 2026)
    Background. Prevention of sports injuries is essential in training programs and recovery complexes for athletes of different level of mastership. Every year, 20-30% of athletes suffer injuries. An effective method of ...
  • Efficacy of myopia-control glasses in managing myopia progression after discontinuation of orthokeratology treatment 
    Arama, Crina; Dumbrăveanu, Lilia; Nastiuc, Sabina; Curca, Stelian; Spoiala, Errica; Bilba, Rodica (CEP Medicina, 2026)
    Background. According to WHO projections, the rising prevalence of myopia warrants increased attention, as approximately 50% of the global population is expected to be affected by 2050. Early intervention in controlling ...
  • Chronic myeloid leukemia: contemporary approaches to diagnosis management 
    Musteață, Vasile; Mereuță, Ion (CEP Medicina, 2026)
    Background. Chronic myeloid leukemia (CML) is characterized by excessive proliferation of myeloid cells, with an increase in the circulating mass and global reservoir of granulocytes, constituting 15-20% of all leukemia ...

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