IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • Genetic factors responsible for ovarian reserve 
    Guțu, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The number of primordial follicles at birth, their quality, and the rate of germ cell depletion are the factors that define reproductive lifespan in women. In some women, oocyte depletion occurs during the ...
  • The cardiotoxicity of local anesthetics 
    Talasimov Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Local anesthetic toxicity is, occasionally, the cause of severe cardiovascular complications. The long-acting local anesthetics as bupivacaine, levobupivacaine and ropivacaine have their toxicity mostly ...
  • Applicability of the CLDQ in the monitoring of patients with delta viral liver cirrhosis 
    Cebanu Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The clinical burden of delta viral cirrhosis is significant in terms of health, quality of life, and economic impact on patients and society. The Chronic Liver Disease Questionnaire (CLDQ) is an instrument ...
  • Chronic obstructive pulmonary disease and depression 
    Avadănii Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic obstructive pulmonary disease encompasses various complications and comorbidities such as respiratory failure, cardiovascular disease, the development of lung cancer, osteoporosis, metabolic syndrome, ...
  • Laboratory markers in the diagnosis of hereditary gluten intolerance 
    Rotari Mădălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gluten intolerance (celiac disease) is a genetic autoimmune disease with a prevalence of approximately 1% of the population in which the consumption of gluten-containing foods causes damage to the small ...
  • Strategies and approaches adopted by community nurses from the Republic of Moldova in promoting a healthy lifestyle 
    Chitoroagă, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Community nurses play a vital role in promoting the health and well-being of the population, particularly in adopting and maintaining a healthy lifestyle. In the Republic of Moldova, these medical professionals ...
  • Indications and limits of gene therapy 
    Doni, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gene therapies represent advanced medical tools that aim to fix or improve genes by correcting mutations or making modifications at a specific site. While there are several successful protocols, it remains a ...
  • Hyperferritinemia in liver diseases - diagnosis and controversies 
    Faraj Shehab (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ferritin is a protein that plays a crucial role in iron storage and regulation within the body. It is found primarily within cells, particularly in the liver, spleen, bone marrow, and other tissues that store ...
  • Treat-to-target strategy in the treatment of rheumatoid arthritis 
    Sufichaev, Simona (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by progressive joint inflammation and structural damage that frequently results in severe disability. Aim of study. The "Treat-to-Target" ...
  • Epilepsy associated with cerebral toxoplasmosis 
    Olaru, Natalia; Dragan, Diana; Vataman, Anatolie; Chiosa, Vitalie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parasitic infections of the central nervous system (CNS) are an acquired cause of epileptic seizures and epilepsy in countries with low and medium economic incomes, including the Republic of Moldova. Cerebral ...
  • RpoB S450L mutation and transmission features of MDR mycobacterium tuberculosis strains in the Republic of Moldova. 
    Chesov, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Republic of Moldova (RM) faces a significant challenge with a high prevalence of multidrug-resistant tuberculosis (MDR-TB). Aim of study. This study aims to explore the potential impact of rpoB S450L ...
  • Bullous pemphigoid, clinical aspects and treatment 
    Caradjova, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bullous pemphigoid is a chronic, potentially fatal autoimmune skin disease that results in generalized pruritic bullous eruptions in older patients. Local and systemic glucocorticosteroid drugs are prescribed ...
  • Role of neurofilament light chain in neurological disease 
    Vasilieva, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Neurofilament light chain (NF-L) is a cytoplasmic protein highly expressed in large-caliber myelinated axons. The degree of axonal damage in a variety of neurological disorders, including inflammatory, ...
  • The role of 3D-printing technologies in oncology - a comprehensive study among medical students 
    Valic, Eugeniu; Valic, Vladimir (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The 3D-printing technologies (3D-PT) are considered as a game-changing way of manufacturing a variety of objects and products with a computer-guided precision. They are used nowadays in various domains, ...
  • Male breast cancer: epidemiology and risk factors 
    Saini, Jai (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Although the prevalence of breast cancer is significantly lower in men than in women, understanding the unique epidemiology and associated risk factors of breast cancer is of paramount importance. This study ...
  • Navigating the challenges of short Bowel syndrome 
    Cucu, Alexandra-Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Short bowel syndrome (SBS) is a rare condition characterized by malabsorption of macronutrients, micronutrients, electrolytes, and water following extensive resection or loss of a significant portion of the ...
  • Study of the chemotherapy treatment of patients with malignant melanoma with distant metastases during the years 2018-2022 within the IMSPIO of the Republic of Moldova 
    Miaun, Cătlin-Cătălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Malignant melanoma is one of the most aggressive malignant tumors in the world, and the incidence and mortality increase annually due to the multitude of risk factors and insufficient information among the ...
  • Malignant tumors in children: epidemiological and evolutionary aspects 
    Rusu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The spectrum of malignant tumors in children differs significantly from that of adults. Whereas adult tumors are the result of cell differentiation from a mature tissue histologically, pediatric tumors originate ...
  • Surgical treatment of cutaneous malignant melanoma 
    Pușcaș, Nina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cutaneous malignant melanoma (MMC) represents a current problem of clinical oncology, the cause being its biological particularities, aggressive evolution and early metastasis. The actuality is determined by ...
  • The occurrence of venous thromboembolism at patients undergoing neoadjuvant chemotherapy 
    Rotaru, Dan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Venous thromboembolism (VTE) is a common complication in cancer patients receiving adjuvant treatment, but its prevalence during neoadjuvant chemo-radiotherapy remains uncertain. Aim of study. This systematic ...