IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • Vaginal cones with vibrating ball inside in pelvic floor dysfunction 
    Villani, Federico; Rigano, Damiano; Moratti, Elisabetta; Minopoli, Bruno; Guglielmino, Alessandra; Todut, Oana; Ciobanu, Victoria; Furau, Roxana; Furau, Cristian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. These are the first results of an ongoing multicentrum observative trial to determine the effectiveness of vaginal cones (VC) in pelvic floor (PF) training. Because of a high economic burden of urine incontinence ...
  • The role of endometrial biopsy in the diagnosis of endometrial hyperplasia 
    Lavric, Irina; Burac. Mihaela; Prepelita, Madalina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Endometrial hyperplasia (EH) is a pathological process of the uterine mucosa characterized by gland proliferation and an increase in the gland-stromal ratio, which develops as a result of excessive estrogenic ...
  • Unintended pregnancy despite IUD, complicated with huge fibroid and scarred uterus, a rare case report 
    Marin, Dimitris; Ciobanu, Victoria; Henegariu, Irina; Furău, Cristian; Furău, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Unintended pregnancy rates remain high as a percentage in adolescents, socioeconomic groups and women that are already closed to the familiar planning. Thus, the variety of contraception methods are increasing ...
  • The influence of pregnancy on the evolution of uterine myoma 
    Guţu, Laura; Găină, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Uterine myoma is a benign, hormone-dependent tumor that occurs more frequently in women aged 25-45. It comprises 30-35% of all gynecological diseases with a correlation between pregnancy and uterine myoma. ...
  • The impact of obesity on pregnant women and fetus 
    Baxan, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity is a condition characterised by excess of body fat and low body mass (BMI ≥ 30). Statistics show that more than 50% of obese and overweight people in Europe are overweight, 26.5% of women of reproductive ...
  • Understanding the impact of covid-19 on pregnancy: a comprehensive study 
    Bambuleac, Iulia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The COVID-19 pandemic has raised concerns about its potential impact on pregnant individuals. This study aims to fill the existing knowledge gap by investigating how COVID-19 affects pregnancy. With the virus ...
  • Gluten intolerance. Celiac disease 
    Volc, Renata (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Celiac disease (CD) is an immune-mediated inflammatory condition of the small intestine that occurs in genetically predisposed individuals when they are exposed to gluten (a plant-based protein component found ...
  • The influence of type 2 pregestational diabetes mellitus on the fetus 
    Surlaru, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of type 2 diabetes among women of reproductive age is increasing. According to the latest data from the International Diabetes Federation in 2019, one in six live births is affected by hyperglycemia ...
  • Mechanisms of action and metabolic effects of anticoagulants 
    Curelariu, Mădălina; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Anticoagulant drugs antagonize coagulation and are used to prevent or prolong the clotting time. Nowadays physicians from different fields possess a broad panel of multiple anticoagulants to meet a patient's ...
  • Decoding AMD: exploring lipofuscin accumulation and metabolomics insights 
    Platon, Angela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Age-related macular degeneration (AMD) represents a multifactorial, degenerative pathology of the retina, with mechanisms that remain incompletely understood. Lipofuscin accumulation is believed to play a ...
  • Biochemical aspects of malabsorption syndromes 
    Burdeniuc, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Malabsorption affects millions of people worldwide. Prevalence of coeliac disease in the general population ranges from 0,5% to 2%, with an average of about 1%. At present over 100,000 people suffer from ...
  • The anatomical variability of the last three pairs of the intercostal arteries 
    Croitoru, Dan; Coșciug, Stanislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The intercostal arteries are of vital significance in the vascularisation of the intercostal musculature, fascia and the ribs. The last three pairs are involved in the blood supply of the antero-lateral ...
  • Variational aspects of the deep femoral artery 
    Nacu, Zinaida (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The deep femoral artery (DFA), also known as the deep artery of the thigh, classically, originates from the lateral semi-circumference of the femoral artery (FA), in the distal direction, at a distance of ...
  • Estrogen therapy - metabolic and clinical consequences 
    Briciuc, Eugenia; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Estrogen therapy has been a cornerstone in the treatment of various medical conditions, especially in menopausal management symptoms, preventing osteoporosis and addressing gynecological concerns. However, ...
  • Corpus callosum agenesis in morphoclinical aspect 
    Rotaraș, Arina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Agenesis of the corpus callosum (ACC) is a congenital brain anomaly, characterized by the absence of commissural fibers connecting the two large hemispheres of the brain. This can be partial or total and can ...
  • Exploring the role of N-terminal pro-brain natriuretic peptide as a diagnostic biomarker in Kawasaki disease 
    Duca, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome, is an acute febrile illness of unknown cause that stands out as a unique and challenging pediatric vasculitis, characterized by acute ...
  • Metabolic peculiarities of immunotherapeutic medicines (chimeric antigen receptor t cells) used in cancer treatment (b-cell acute lymphoblastic leukemia) 
    Sluchin, Andrei (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In the dynamic realm of cancer therapeutics, many studies explore the metabolic nuances of Chimeric Antigen Receptor (CAR) T-cell therapy in treating B-cell acute lymphoblastic leukemia (B-ALL). Understanding ...
  • The interplay of growth hormone, insulin-like growth factors, and cancer susceptibility: a medical perspective 
    Briceag, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. GH and IGF-I, known for promoting growth, are under scrutiny for their potential involvement in cancer progression. While we understand their normal effects, the disruption caused by these factors and their ...
  • Variation of the mastoid segment of the facial canal and of the stylomastoid foramen 
    Ashkar, Laila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Taking into consideration that the ratio of the facial nerve iatrogenic injuries in primary mastoidectomy is 0.6%-3.7%, and a twice higher ratio of 4%-10% is reported for the revision surgery, the knowledge ...
  • Biochemical aspects of heart diseases in patients with diabetes mellitus 
    Parapuravalappil Sathyan, Krishnadas (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of diabetes mellitus is continuously increasing globally and is estimated to reach approx. 366 million by 2030. According to the latest research, the cardiovascular changes due to diabetes are ...