MedEspera: International Medical Congress for Students and Young Doctors: Recent submissions

  • Endocrine changes and menstrual dysfunctions in adolescent girls with obesity 
    Solcanu, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent decades, there has been a significant increase in the obesity rate among adolescent girls. According to the specialized literature, obesity induces hormonal changes that have consequences on sexual ...
  • HPV status and associated precursor lesion in vulvar squamous cell carcinoma 
    Butnaru, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There are distinctive precursor lesions related to vulvar squamous cell carcinoma (VSCC) that are associated with high-risk human papillomavirus (HPV) type 16,18 specifically vulvar intraepithelial neoplasia ...
  • Advancing Parkinson's disease management: novel strategies and therapeutic innovations 
    Budianu, Cătălina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parkinson's disease is a long-term neurodegenerative condition of the central nervous system that mainly affects the control of voluntary movements due to the gradual degeneration of dopaminergic neurons ...
  • Contemporary approaches to the treatment of frontotemporal dementia 
    Iarovoi, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Frontotemporal dementia or FTD relates to a group of diseases that are caused by neuronal degeneration. FTD is mainly of genetic etiology, due to mutations occurring in specific genes, and may be transmitted ...
  • Mesenchymal stem cell-derived exosomes and their antineoplastic potential 
    Louka, George (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Mesenchymal stem cells (MSC) are pluripotent cell types derived from mesenchyme able to differentiate and proliferate into a variety of tissues. Exosomes derived from MSC exhibit a round morphology (40-160 ...
  • Gene therapy for adenosine deaminase severe combined immunodeficiency (ADA-SCID) 
    Bogdanov, Alan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. About 1 in 500,000 people are born with severe combined immunodeficiency (SCID). The adenosine deaminase variant is a fatal inborn error of purine metabolism. Accumulation of adenosine and deoxyadenosine ...
  • Combination of beta-blockers with ace inhibitors in the treatment of hypertension in patients with cardiac comorbidities 
    Ticlenco, Teodorina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Approximately 1.28 billion people worldwide are estimated to have hypertension, and it can either promote or accompany other cardiac comorbidities. The combination of betablockers with angiotensin-converting ...
  • Mechanisms of drug-induced nephrotoxicity 
    Iapara, Olga (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Drug-induced nephrotoxicity or drug-induced renal disease (DRID) is a common clinical problem. It has been reported that the incidence of drug-induced renal disease in adults can range from 14-26% to 66% ...
  • Drugs of choice in hypertensive emergency associated with acute aortic dissection 
    Prijilevschi, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acute aortic dissection is a hypertensive emergency that requires an immediate reduction of blood pressure (BP) by administering intravenous drug therapy. Diligent control of BP is the most crucial in order ...
  • Acute drug intoxication - a modern look at old problem 
    Zveaghintev, Piotr (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acute drug intoxication is a persistent and critical problem in the modern healthcare landscape. Study of the problem in recent years has marked an increase in the incidence of acute poisoning. Given the ...
  • Dapagliflozin as an SGLT2 inhibitor and its effect on the treatment of type 2 diabetes 
    Minchevici, Delia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sodium-glucose cotransporter 2 (SGLT2) inhibitors represent a drug class commonly used in the management of type 2 diabetes. Aim of study. Dapagliflozin demonstrated a significant decrease in the occurrence ...
  • The ways to improve drug stability 
    Cojocari, Cristina; Mazur, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The stability of medicine represents capacity to maintain physical, chemical, biological and microbiological stability. It directly influences the effectiveness and safety of drugs. Aim of study. To elucidate ...
  • The pharmacist's role in the therapeutic partnership relationship with the elderly patient 
    Diaconu, Alina; Șchiopu, Tatiana; Groian, Alexandra; Adauji, Stela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The collaboration between the pharmacist and the elderly in the community pharmacy is being defined through a therapeutic partnership that ensures the quality of pharmaceutical care provided. This relationship ...
  • Chronotype in patients with sleep apnea headaches 
    Candice, Dreyah (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronotype describes the hormonal schedule of an individual that makes them naturally inclined to a specific sleep pattern or period of alertness in a day, and unlike circadian rhythm, which describes a ...
  • The use of magnesium salts in the therapy of arterial hypertension 
    Nicolăescu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Annually, more than 10 million lives are lost due to high blood pressure (HT). A low magnesium content in drinking water leads to increased risk of developing cardiovascular disease (especially coronary ...
  • Chronic stress and its inducing factors in a group of second-year medical students 
    Andrieș, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. General medicine is one of the most prestigious academic fields in the Republic of Moldova. The study of general medicine is considered one of the most demanding, both in terms of the volume of information, ...
  • The role of polymers in the development of some adhesive forms 
    Berzan, Vladislava (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Oropharyngeal preparations represent a modern trend in the technology of solid forms, which have been developed to overcome some disadvantages of other forms (complex manufacturing, variable stability). ...
  • Autonomic nervous system activity parameters in individuals with affective disorders 
    Rudic, Ciprian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Studies have shown a potential correlation between affective disorders and disturbances in the autonomic nervous system (ANS) activity, particularly heart rate variability (HRV). HRV is observed to be reduced ...
  • Infectious complications after caesarean delivery 
    Zuico, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cesarean delivery, also known as a C-section, is characterized by the delivery of a fetus through surgical incisions performed on both the abdominal wall (laparotomy) and the uterine wall (hysterotomy). ...
  • The impact of COVID-19 disease on platelets and coagulation 
    Vartic, Iana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Platelets are formed elements of blood that play an important role in blood clotting. As the main mediator of thrombus formation, platelets have become one of the key aspects in the study of SARS-CoV-2. ...

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