Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova: Recent submissions

  • Evaluation of the rationality of perioperative antibiotic prophylaxis 
    Coretchi, Ianoș; Garaba, Cristina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Irrational perioperative antibacterial prophylaxis increases microbial resistance, treatment cost, and length of hospital stay. Objective of the study. Evaluation of the rationality of perioperative antibiotic ...
  • Evaluation of serum and tissue nitric oxid levels in patients with nasal polyposis 
    Istratenco, Ala (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Nasal polyposis (NP) - a multifactorial pathology with negative impact on quality of life. The pathogenesis of NP has not yet been fully elucidated. This limits the pathogenic treatment. Recent studies suggest ...
  • The level of knowledge and attitude towards adverse drug reaction reporting 
    Guțanu, Diana; Corețchi, Ianoș; Țurcan, Lucia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The action of drugs is like a balance, on the one side being placed the benefits and on the other the risks. Each drug has a wide range of adverse reactions, so their detection, analysis and reporting have a ...
  • The influence of entomological preparations on oxidative stress in subacute inflammation 
    Guțu, Ina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The role of oxidative stress in the evolution of inflammation is demonstrated. Preparations of entomological origin have revealed antioxidant effect in various pathological processes. Objective of the study. ...
  • Changes of glutathione peroxidase activity in the blood serum on the administration of some local coordination compounds 
    Pantea, Valeriana; Popa, Veaceslav; Fulga, Ala; Șveț, Inna; Tagadiuc, Olga (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Testing of new remedies to correct the redox imbalance are of particular interest. In this aspect an important role is assigned to glutathione peroxidase - the key enzyme, maintaining the optimum level of ...
  • The prognostic value of D-Dimer in COVID-19 infection 
    Martîn, Cristina; Tagadiuc, Olga (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The infection with novel Coronavirus (COVID-19) represents a new form of infection, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Thrombotic complications are manifested paraclinically ...
  • Value of some biomarkers of oxidative stress in patients with coraliform nephrolithiasis and chronic calculated pyelonephritis 
    Rotaru, Liliana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Coral nephrolithiasis and chronic calculous pyelonephritis have an important medical and social impact on quality of life and professional or extra-professional performance. Objective of the study. The study ...
  • Carrier frequency of the 35delG mutation in GJB2 gene in the moldavian population 
    Buza, Anastasia; Parii, Sergiu; Butovscaia, Cristina; Galea-Abdusa, Daniela; Curocichin, Ghenadie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The single-nucleotide guanine deletion 35delG in GJB2 exon 2 is the leading pathogenic mutation for up to 70% of cases of congenital nonsyndromic sensorineural hearing loss (NSHL) among Europeans. The early ...
  • Pulmonary embolism syndrome 
    Ursan, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Pulmonary embolism is a common complication of deep vein thrombosis (DVT) or the penetration of amniotic fluid into the maternal circulation. Risk factors include varicose vein disease of the lower limbs, use ...
  • Updates in laboratory diagnosis of primary immunodeficiencies 
    Ivanciuc, Daniela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Primary immunodeficiency disorders (PID) comprise more than 150 disorders that affect the development and/or function of the immune system. PID has the greatest diagnostic burden due to the complexity and ...
  • Role of adipokines in the pathogenesis of atherosclerosis 
    Ostap, Felicia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Obesity is one of the modifiable cardiovascular risk factors. Adipokines, which represent a series of hormones and cytokines secreted by adipose tissue, seem to explain the correlation between obesity and ...
  • Colchicine induced hepatotoxicity: a case report and literature review 
    Caracaș, Anastasia; Vasilache, Eugenia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Colchicine demonstrates the greatest anti-mitotic activity on rapidly dividing tissue and has only infrequently been associated with hepatotoxicity. It has usually been associated with cases of overdose in ...
  • Drug-induced ventricular arrhytmogenesis in patients with COVID-19. A literature review 
    Lablic, Anastasia; Feghiu, Iuliana; Baltaga, Ruslan (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Several existing medications are being repurposed for treatment of COVID-19, including chloroquine and hydroxychloroquine. The use of these medications has been associated with QT prolongation. Their use in ...
  • The role of micro-RNA in fibrinolysis 
    Dumitraș, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Micro-RNAs (miRNAs) were defined as small endogenous non-coding RNAs consisting of 18-24 nucleotides, responsible for the gene expression and involved in many cellular processes. The exact role of miRNA in ...
  • miRNA in oncological pathology: ovarian cancer 
    Pojoga, Maria-Magdalena; Vicol, Adrian (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. miRNAs errors and their defective interference in regulation of gene expression, as well as their long distance action can be correlated with the development and malignization of ovarian cancer, affecting ...
  • The quality of sleep in high school urban students 
    Dumitraș, Mariana; Lupușor, Adrian; Vovc, Victor (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. High school students, in their adolescence age, need at least 8-9 hours of good quality sleep. Their sleeping problems are thought to be due to late melatonin secretion and bad sleep habits, especially in the ...
  • The role of metalloproteinases (MMPS) in tumor development 
    Spoială, Augustina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. MMPs are a family of proteinases that regulate cell behavior by remodeling stromal and cell surface proteins, thereby influencing cell survival, genomic stability, and differentiation. MMPs are key players ...
  • Predictive power of RTS, ASCOT, NISS, ISS and TRISS scores in severe trauma patients from Republic of Moldova. Preliminary data 
    Grabovschi, Ion (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Attempts to predict the evolution course of the pathological conditions led to the traumatic scores’ elaboration based on the distinct medical systems realities that differ in many respects from the local ...
  • The importance of c-reactive protein (CRP) in respiratory infections 
    David, Adrian-Bogdan (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. CRP is a homopentamer protein, an acute phase reactant, present in tissue damage and inflammation. The mechanisms by which it activates the complement, induces apoptosis, phagocytosis, the production of NO ...
  • The role of angiotensin-converting enzyme 2 into the patogenesis of COVID-19 infection 
    Toma, Alina; Vișnevschi, Anatolie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The angiotensin-converting enzyme 2 (ACE2) is an exopeptidase that catalyzes the conversion of angiotensin II to angiotensin 1-7. ACE2 receptor has recently been identified as the entry point of the severe ...

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