Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova by Issue Date

Browsing Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova by Issue Date

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  • Clinical manifestations, diagnostic and contemporary treatment of chronic granulocitary leukemia 
    Ungureanu, Cezara; Plamadeala, Natalia; Dancuța, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Chronic granulocytic leukemia is a chronic myeloproliferative disease characterized by the presence of translocation t(9;22)(q34;q11), also know as the Ph1 and/or BCR-ABL rearrangement. Causal factors remain ...
  • Changes of glutathione peroxidase activity in the blood serum on the administration of some local coordination compounds 
    Pantea, Valeriana; Popa, Veaceslav; Fulga, Ala; Șveț, Inna; Tagadiuc, Olga (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Testing of new remedies to correct the redox imbalance are of particular interest. In this aspect an important role is assigned to glutathione peroxidase - the key enzyme, maintaining the optimum level of ...
  • The importance of c-reactive protein (CRP) in respiratory infections 
    David, Adrian-Bogdan (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. CRP is a homopentamer protein, an acute phase reactant, present in tissue damage and inflammation. The mechanisms by which it activates the complement, induces apoptosis, phagocytosis, the production of NO ...
  • Molecular and genetic aspects of senescence 
    Pădure, Cătălina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Senescence is the last stage of the physiological development of the human body, in which the cell division stops and the accumulation of damaged cells takes place. Trigger factors are DNA damage, telomere ...
  • The role of metalloproteinases (MMPS) in tumor development 
    Spoială, Augustina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. MMPs are a family of proteinases that regulate cell behavior by remodeling stromal and cell surface proteins, thereby influencing cell survival, genomic stability, and differentiation. MMPs are key players ...
  • The influence of entomological preparations on oxidative stress in subacute inflammation 
    Guțu, Ina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The role of oxidative stress in the evolution of inflammation is demonstrated. Preparations of entomological origin have revealed antioxidant effect in various pathological processes. Objective of the study. ...
  • Predictive power of RTS, ASCOT, NISS, ISS and TRISS scores in severe trauma patients from Republic of Moldova. Preliminary data 
    Grabovschi, Ion (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Attempts to predict the evolution course of the pathological conditions led to the traumatic scores’ elaboration based on the distinct medical systems realities that differ in many respects from the local ...
  • Predictive model of treatment result in polytraumatism 
    Arnaut, Oleg (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Assessing the severity of the injuries, as well as estimating the polytrauma patient’s prognosis are the key moments in their management. Predictive models for polytrauma treatment outcome are poorly described ...
  • Diagnosis of chronic lymphocytic leukemia 
    Motreac, Cristina; Bîcu, Ionela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Chronic lymphocytic leukemia is oncohematological pathologies characterized by the progressive accumulation of monoclonal lymphocytes in blood, bone marrow and lymphoid tissues. In the majority of cases ...
  • The level of knowledge and attitude towards adverse drug reaction reporting 
    Guțanu, Diana; Corețchi, Ianoș; Țurcan, Lucia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The action of drugs is like a balance, on the one side being placed the benefits and on the other the risks. Each drug has a wide range of adverse reactions, so their detection, analysis and reporting have a ...
  • Cytogenetic analysis in men with azoospermia 
    Racoviță, Stela; Moșin, Veaceslav; Capcelea, Svetlana; Mișina, Anna; Cemortan, Igor; Sprincean, Mariana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. It is estimated that one in six couples are infertile for different reasons, and the male factor is involved in half of the cases. Azoospermia is detected in up to 8% of male infertility situations. The prevalence ...
  • Disorders of catalase activity in hypertensive retinopathy 
    Pavlovschi, Ecaterina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. The pathobiochemical mechanism of hypertensive retinopathy (HR) is with certainty not established. High blood pressure by itself could not explain the retinal changes that occur, therefore additional pathogenetic ...
  • The role of micro-RNA (miRNA) in development of lymphomas 
    Nica, Loredana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Small miRNA molecules, non-coding, regulate the expression of approximately 2/3 of total human genes, most of which are located in cancer-associated genomic regions. Moreover, in all types of cancer an abnormal ...
  • Evaluation of serum and tissue nitric oxid levels in patients with nasal polyposis 
    Istratenco, Ala (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Nasal polyposis (NP) - a multifactorial pathology with negative impact on quality of life. The pathogenesis of NP has not yet been fully elucidated. This limits the pathogenic treatment. Recent studies suggest ...
  • Changes in vegetative heart tonus after endotracheal intubation during induction of general anesthesia with propofol and fentanyl 
    Smelansky, Emily Ghenady; Feghiu, Iuliana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Induction of general anesthesia, especially the stage of endotracheal intubation is frequently associated with changes in heart rhythm and cardiac arrhythmias triggered by changes in vegetative tonus of the ...
  • Native vegetable oils: properties and mechanisms 
    Rakovskaia, Tatiana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Vegetable oils with lipophilic compounds (polyunsaturated fatty acids, tocopherols, phytosterols, carotenoids, organic acids, alcohols, esters, aldehydes, ketones) and hydrophilic (phenolic acids, aldehydes, ...
  • Evaluation of the rationality of perioperative antibiotic prophylaxis 
    Coretchi, Ianoș; Garaba, Cristina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Irrational perioperative antibacterial prophylaxis increases microbial resistance, treatment cost, and length of hospital stay. Objective of the study. Evaluation of the rationality of perioperative antibiotic ...
  • Evaluation of MELD score and derived MELD scores in the prediction of short-term mortality after liver transplantation 
    Iurciuc, Vladislav; Hotineanu, Adrian; Taran, Natalia; Berliba, Elina; Toaca, Inesa (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. MELD score and derived MELD scores estimate survival at 3 months in patients with decompensated liver cirrhosis on the waiting list for liver transplantation. It is unclear whether these scores would be ...
  • The impact of the rehabilitation methods in children with Type 1 diabetes mellitus – an update 
    Eșanu, Valeriu; Palii, Ina; Golovin, Boris; Chiriac, Andrian (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. In children with Type 1 diabetes mellitus (T1DM) is necessary to implement prevention and treatment measures, aimed to reduce the risk of premature morbidity and mortality. Objective of the study. To evaluate ...
  • Epileptic spasms in children: clinical - electroencephalographic aspects 
    Feghiu, Ludmila; Hadjiu, Svetlana; Călcîi, Cornelia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2020)
    Background. Epileptic spasms (ES) are common in West syndrome (WS), a devastating encephalopathy, common in children up to 2 years, of various etiologies, such as: structural disorders of the brain and chromosomes, ...

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