Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing Cells and Tissues Transplantation. Actualities and Perspectives: The Materials of the National Scientific Conference with International Participation, the 4 th edition, Chisinau, March 20-21, 2026 by Issue Date

Browsing Cells and Tissues Transplantation. Actualities and Perspectives: The Materials of the National Scientific Conference with International Participation, the 4 th edition, Chisinau, March 20-21, 2026 by Issue Date

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  • The role of angiogenesis in ischemic disease 
    Grusac, Evgheni; Cebotari, Dionisie; Railean, Nadejda; Oboroc, Sandu; Sardari, Veronica (CEP Medicina, 2026)
    Background. Ischemic heart disease, myocardial infarction, ischemic stroke, and peripheral arterial disease are non-communicable, highly disabling conditions with high incidence and mortality rates. It is well recognized ...
  • Strategies for mitigating oxidative stress in transplanted cells 
    Satheswaran, Maharajan; Cebotari, Dionisie; Railean, Nadejda; Tagadiuc, Olga; Sardari, Veronica (CEP Medicina, 2026)
    Introduction. Transplantation is a vital treatment for organ failure, degenerative diseases and severe tissue injuries. Challenge being, the poor function, survival of transplanted cells caused by oxidative stress. During ...
  • Evaluation of BCL-2 expression in 33 consecutive cases of serous ovarian carcinoma 
    Mărițoi, Tatiana; Pînzaru, Valeria; Tașci, Xenia; Fulga, Veaceslav; Șaptefrati, Lilian; David, Valeriu (CEP Medicina, 2026)
    Introduction: Serous ovarian carcinoma, the most frequent subtype, exhibits aggressive behavior and late diagnosis. The BCL-2 protein, with its anti-apoptotic role, promotes tumor cell survival. BCL-2 expression is ...
  • Spectral analysis of the submandibular gland sialoliths 
    Lehtman, Sofia; Babuci, Angela; Motelica, Gabriela; Zorina, Zinovia; Dandara, Mihaela; Procopenco, Olga (CEP Medicina, 2026)
    Introduction. Sialoliths are intraductal or intraparenchymal calculi of the large salivary glands. They consist of organic and inorganic mater, with a nucleus and plastic peripheral structures. The sialoliths predominantly ...
  • The role of copper in angiogenesis 
    Grusac, Evgheni; Pantea, Valeriana; Railean, Nadejda; Stratulat, Silvia; Sardari, Veronica (CEP Medicina, 2026)
    Background. In disease conditions, the goal of therapeutic targeting of the angiogenic process is to normalize vasculature in target tissues by enhancing angiogenesis, where reduced vascularity and blood flow occur, such ...
  • Anatomical clinical aspect in the etiology of inguinal hernia 
    Guzun, Gheorghe; Turchin, Radu (CEP Medicina, 2026)
    Background. Decreased tone of the anterolateral abdominal wall muscles, actually is considered the main etiological factor in the appearance of inguinal hernia. Taking into consideration that the spinal nerves have the ...
  • ADSC - enriched autologus fat grafting in facial rejuvenation 
    Tripadus, Cristiana; Ghețiu, Alexandru; Chele, Nicolae; Sîrbu, Dumitru (CEP Medicina, 2026)
    Introduction: Autologous fat transfer (AFT) is widely applied in facial rejuvenation due to its biocompatibility and capacity to restore age-related volume loss. Although patient satisfaction remains high, long-term ...
  • The role of angiogenesis in osteoarthritis 
    Basistii, Alexander; Pulucciu, Elena; Grusac, Evgheni; Bețisor, Alexandru; Cepoi, Daniela; Sardari, Veronica (CEP Medicina, 2026)
    Background. Osteoarthritis (OA), a degenerative joint disease, involves synovial inflammation, subchondral bone erosion, and cartilage degeneration affecting nowadays more than 630M people worldwide for which there is ...
  • In vitro modulation of pseudocholinesterase activity by Cu-thiosemicarbazone compounds in rat C6 glioma cells 
    Pantea, Valeriana; Pavlovschi, Ecaterina; Sardari, Veronica; Șveț, Inna; Tagadiuc, Olga (CEP Medicina, 2026)
    Introduction. Glioma represents one of the most aggressive forms of primary tumors of the central nervous system, characterized by rapid proliferation, high invasiveness, and resistance to conventional therapies. The C6 ...
  • Lymphatic tissue engineering: experience of the laboratory of tissue engineering and cell culture at Nicolae Testemitanu State University of Medecine and Pharmacy 
    Aparece, Alexandra; Jian, Mariana; Cobzac, Vitalie; Nacu, Ana-Maria; Hîncota, Dumitru; Verega, Grigore; Nacu, Viorel; Stoian, Alina (CEP Medicina, 2026)
    Introduction: Lymphedema (LE) is a chronic and progressive disease caused by damage to lymphatic vessels and/or lymph nodes (LNs). Conservative treatment includes complex decongestive therapy, physiotherapy, exercise, ...
  • Cellular therapy in diabetic retinopathy 
    Vicol, Catalina; Nacu, Viorel (CEP Medicina, 2026)
    Introduction. Diabetic retinopathy is one of the most common microvascular complications of type 1 and type 2 diabetes and a major cause of visual impairment and blindness in adults. Its pathogenesis involves complex ...
  • Methods for inducing glaucoma in animal models: experimental approaches and research applications 
    Țarălungă, Tatiana; Scheghelskaya, Elena; Țarălungă, Maxim; Vicol, Adrian; Iacubițchi, Maria; Paduca, Ala; Bendelic, Eugeniu; Nacu, Viorel (CEP Medicina, 2026)
    Introduction. Glaucoma is a leading cause of irreversible blindness worldwide, characterized by progressive optic neuropathy and retinal ganglion cell loss, often associated with elevated intraocular pressure. Experimental ...
  • Correlation between the width of the facial nerve trunk and greater auricular nerve 
    Babuci, Angela; Midrigan, Corina; Zorina, Zinovia; Bendelic, Anastasia; Ostahi, Nadia; Botnari, Tatiana; Botnaru, Doina; Lehtman, Sofia; Motelică, Gabriela; Nastas, Liliana (CEP Medicina, 2026)
    Introduction. Surgical repair of the facial nerve trunk (FNT) after iatrogenic injures, trauma or tumor removal is one of the primary goals in head and neck surgery. As grafts for facial nerve repair in large nerve defects ...
  • Kinking sydrome of the abdominal aorta: case presentation 
    Botnari, Tatiana; Zorina, Zinovia; Babuci, Angela; Cealan, Andrei; Catereniuc, Ilia; Botnaru, Doina; Ostahi, Nadia (CEP Medicina, 2026)
    Introduction: Abdominal aortic kinking syndrome is a rare congenital malformation characterized by angulation of the abdominal aorta (AA), which, depending on the degree of inflection, can alter the origin and trajectory ...
  • Brainstem in morphoclinical aspect 
    Armașula, Mihaela; Zorina, Zinovia (CEP Medicina, 2026)
    Introduction. Morphoclinical analysis of the brainstem is essential due to its structural complexity and the severity of associated disorders. Stroke represents the main acute neurological pathology, presenting a wide ...
  • Lung transplantation in the management of cystic fibrosis 
    Rotaru, Ludmila; Rotaru, Tudor (CEP Medicina, 2026)
    Introduction. Cystic fibrosis (CF) is an autosomal recessive genetic disorder caused by mutations in the CFTR gene, affecting multiple organs, particularly the lungs, and leading to progressive respiratory failure. Despite ...
  • The immediate and delayed loading of dental implants 
    Melnic, Svetlana; Uncuța, Diana; Poștaru, Cristina (CEP Medicina, 2026)
    Introduction: Implant supported restorations for partially edentulous patients are a well-accepted and predictable treatment modality. Provisional restorations may be used at the time of implant placement or after an ...
  • Perinatal stem cells in regenerative medecine and transplantation: current applications and future perspectives 
    Mudzhuk, Alona; Nacu, Viorel (CEP Medicina, 2026)
    Introduction. The preservation of perinatal biological materials - umbilical cord blood, umbilical cord tissue, and placental tissue - has become one of the most important developments in modern preventive and regenerative ...
  • Implementing regenerative medecine across surgical pathways in liver cirrhosis 
    Negarî, Nadejda; Minchevici, Delia; Cazacov, Vladimir; Nacu, Viorel (CEP Medicina, 2026)
    Introduction: Liver cirrhotic patients often face surgical and interventional procedures, such as hepatectomy with modulation of future liver remnant, portoenterostomy in cases of biliary atresia, transjugular intrahepatic ...
  • Restoring thyroid function with tissue-engineered products after total thyroidectomy 
    Minchevici, Delia; Negarî, Nadejda; Bour, Alin; Gîlea, Angela; Nacu, Viorel (CEP Medicina, 2026)
    Introduction: Post-thyroidectomy hypothyroidism is a common complication of total thyroid removal, traditionally managed with lifelong hormone replacement therapy. Thyroid models developed through tissue engineering ...

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