Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing Cells and Tissues Transplantation. Actualities and Perspectives: The Materials of the National Scientific Conference with International Participation, the 4 th edition, Chisinau, March 20-21, 2026 by Issue Date

Browsing Cells and Tissues Transplantation. Actualities and Perspectives: The Materials of the National Scientific Conference with International Participation, the 4 th edition, Chisinau, March 20-21, 2026 by Issue Date

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  • Diabetogenic efect of immunosuppressive drugs in transplant recipients 
    Mihalachi-Anghel, Maria; Bacinschi-Gheorghița, Stela; Bacinschi, Nicolae (CEP Medicina, 2026)
    Introduction. In organ transplant patients, new onset diabetes mellitus after transplantation (NODAT) has been found to be a frequent and serious complication. The use of immunosuppressive drugs after transplantation has ...
  • Thirteen years of activity of the human tissue bank at the clinical hospital of orthopedics and traumatology 
    Nacu, Viorel; Stepa, Serghei; Cospormac, Igor; Cociug, Adrian; Cobzac, Vitalie; Țîmbalari, Tatiana (CEP Medicina, 2026)
    Introduction. Tissue transplantation represents an essential component of modern regenerative and reconstructive medicine. In the Republic of Moldova, this field has evolved progressively since the 1960s, beginning with ...
  • Tumour thickness as a prognostic factor in the evolution of cutaneous malignant melanoma 
    Cenușa, Alexandrina; Foca, Ecaterina; Carpenco, Ecaterina; Brînză, Dumitru; David, Valeriu; Șaptefrați, Lilian; Fulga, Veaceslav (CEP Medicina, 2026)
    Introduction. Cutaneous malignant melanoma is a biologically heterogeneous neoplasm characterized by marked variability in clinical behaviour and prognosis. Although, multiple histopathologic parameters are incorporated ...
  • ADSC - enriched autologus fat grafting in facial rejuvenation 
    Tripadus, Cristiana; Ghețiu, Alexandru; Chele, Nicolae; Sîrbu, Dumitru (CEP Medicina, 2026)
    Introduction: Autologous fat transfer (AFT) is widely applied in facial rejuvenation due to its biocompatibility and capacity to restore age-related volume loss. Although patient satisfaction remains high, long-term ...
  • The role of angiogenesis in osteoarthritis 
    Basistii, Alexander; Pulucciu, Elena; Grusac, Evgheni; Bețisor, Alexandru; Cepoi, Daniela; Sardari, Veronica (CEP Medicina, 2026)
    Background. Osteoarthritis (OA), a degenerative joint disease, involves synovial inflammation, subchondral bone erosion, and cartilage degeneration affecting nowadays more than 630M people worldwide for which there is ...
  • Decreased melanogenic activity correlate with enhanced aggressiveness of cutaneous malignant melanoma 
    Cenușa, Alexandrina; Foca, Ecaterina; Carpenco, Ecaterina; Brînză, Dumitru; David, Valeriu; Șaptefrați, Lilian; Fulga, Veaceslav (CEP Medicina, 2026)
    Introduction. Cutaneous malignant melanoma exhibits marked heterogeneity in clinical behaviour and histopathologic appearance. Although tumour thickness, Clark level, and invasive growth patterns remain key prognostic ...
  • Lymphatic tissue engineering: experience of the laboratory of tissue engineering and cell culture at Nicolae Testemitanu State University of Medecine and Pharmacy 
    Aparece, Alexandra; Jian, Mariana; Cobzac, Vitalie; Nacu, Ana-Maria; Hîncota, Dumitru; Verega, Grigore; Nacu, Viorel; Stoian, Alina (CEP Medicina, 2026)
    Introduction: Lymphedema (LE) is a chronic and progressive disease caused by damage to lymphatic vessels and/or lymph nodes (LNs). Conservative treatment includes complex decongestive therapy, physiotherapy, exercise, ...
  • Antibiotic time-out as an effective antimicrobial stewardship strategy: reduced duration, preserved clinical outcomes 
    Rabbi, Syeda; Catcov, Carolina (CEP Medicina, 2026)
    Background. Prolonged antibiotic therapy remains common, despite shorter guideline durations. Overexposure to antibiotics has reported negative impacts in patients, such as an increase in resistant, invasive fungal ...
  • PAX5 expression in breast carcinoma 
    Portnoi, Elena; Brînza, Dumitru; Foca, Ecaterina; Adam, Consuela; Pînzaru, Valeria; Stratan, Valentina; Fulga, Veaceslav (CEP Medicina, 2026)
    Introduction. PAX5 is a transcription factor essential for B-cell lineage differentiation, but recent studies suggest its involvement in other types of neoplasms, including breast carcinoma. Understanding PAX5 expression ...
  • Cellular therapy in diabetic retinopathy 
    Vicol, Catalina; Nacu, Viorel (CEP Medicina, 2026)
    Introduction. Diabetic retinopathy is one of the most common microvascular complications of type 1 and type 2 diabetes and a major cause of visual impairment and blindness in adults. Its pathogenesis involves complex ...
  • The development of low-cost simulators for medical training in punctures 
    Adam, Alexandru; Gonta, Kristi; Florea, Constantin; Prozorovschi, Daniel; Nacu, Viorel (CEP Medicina, 2026)
    Introduction. Medical procedures involving punctures require practical training for outmost effectiveness and low risks. Therefore, a project with the purpose of training medical students was developed constructing 4 ...
  • The molecular substrate of the human species: differencies between male and female sex 
    Catînsus, Patricia; Babuci, Angela (CEP Medicina, 2026)
    Introduction. Delegates of the same species – Homo Sapiens, males and females present strong contrasts which concern cognition, passions, goals and lifestyle. These differences are beyond the two completely unsimilar ...
  • Microsurgical replantation of the first digit following traumatic metacarpal-level amputation 
    Țarălungă, Maxim; Vicol, Adrian; Calistru, Anatolie (CEP Medicina, 2026)
    Introduction. Replantation of the first digit is one of the most complex and functionally significant procedures in hand microsurgery, due to its essential role in thumb opposition, grasp, and overall upper limb performance. ...
  • Tumor-infiltrating CD79α positive lymphocytes in breast cancer 
    Portnoi, Elena; Brînza, Dumitru; Foca, Ecaterina; Adam, Consuela; Pînzaru, Valeria; Stratan, Valentina; Fulga, Veaceslav (CEP Medicina, 2026)
    Introduction. Tumor-infiltrating lymphocytes (TILs) represent a critical component of the immune microenvironment in breast cancer, influencing tumor progression and patient prognosis. Among Bcell markers, CD79α is a ...
  • Metabolic effects and use of glucocorticoids in athletes 
    Ranev, Andreea; Timercan, Tatiana (CEP Medicina, 2026)
    Introduction. Glucocorticoids are hormones secreted by the adrenal cortex, playing an essential role in regulating basal metabolism and the inflammatory response. Due to their metabolic effects, glucocorticoids are ...
  • A case of arteriovenous malformation 
    Răcilă, Gheorghina; Zorina, Zinovia (CEP Medicina, 2026)
    Introduction. Arteriovenous malformations (AVM) are part of the group of cerebral vascular malformations that represent congenital defects of the circulatory system formed by a cluster of blood vessels through which ...
  • Role of cellular and molecular factors in alveolar ridge remodeling after tooth loss 
    Abaev, Eital; Babuci, Angela; Zorina, Zinovia (CEP Medicina, 2026)
    Introduction: The bone remodeling after the tooth loss is a complex process that occurs at the cellular level, being regulated by a complex mechanism, maintaining the balance between the bone resorption, influenced by ...
  • Synovial tissue in the functioning of synovial joints and the occurrence of ostheoarthritis 
    Labusca, Luminita (CEP Medicina, 2026)
    Synovial joints have traditionally been interpreted through a cartilage-centric framework, with synovial tissue often viewed primarily as a secondary responder to cartilage damage. However, increasing experimental and ...
  • Selenium-dependent glutathione peroxidase 4 regulation of ferroptosis: applications in graft survival and oncological therapy 
    Cebotari, Dionisie; Grusac, Evgheni; Railean, Nadejda; Tagadiuc, Olga; Sardari, Veronica (CEP Medicina, 2026)
    Introduction: Selenium is a fundamental micronutrient required for biosynthesizing glutathione peroxidase 4, a key antioxidant enzyme responsible for maintaining cellular redox homeostasis. Its primary biochemical function ...
  • Human collagen-based hydrogel with zinc oxide nanoparticles for articular cartilage engineering 
    Cobzac, Vitalie; Cojocari, Ștefan; Jian, Mariana; Stoian, Alina; Nacu, Ana-Maria; Motelica, Ludmila; Trusca, Roxana; Ficai, Anton; Nacu, Viorel (CEP Medicina, 2026)
    Introduction. Articular cartilage tissue engineering has a long history of using three-dimensional matrices seeded with cells of chondrogenic potential. Recent studies show that chondrogenesis is influenced not only by ...

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