IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • Cardiotoxicity induced by contemporary oncologic therapies: early biomarkers and practical clinical algorithms 
    Chetrean, Cristina; Gutium, Iulian; Gutium, Loredana; Potop-Rotari, Dorina; Tcaciuc, Angela (CEP Medicina, 2026)
    Background. Anticancer therapies (anthracyclines, anti-HER2 agents, PD-1/PD-L1 inhibitors) reduce cancer-related mortality; however, they are associated with cardiotoxicity. According to the ESC guidelines, hs-cTn and ...
  • Dimensiuni demografice, medicale și sociale ale sănătății populaționale în era antibioticorezistenței 
    Ferdohleb, Alina; Spinei, Larisa; Țapu, Livia; Ciobanu, Elena; Croitoru, Cătalina; Iaconi, Oana-Simina; Burduniuc, Olga; Balan, Greta (Asociaţia chirurgilor “Nicolae Anestiadi” din Republica Moldova, 2026)
    Rezumat. Introducere. Rezistența la antimicrobiene (RAM) compromite eficiența tratamentelor antiinfecțioase și contribuie semnificativ la pierderi evitabile de ani de viață sănătoasă. Impactul său este tot mai frecvent ...
  • Trunchiul celiac: variante anatomice și malformații – revizuire narativă a literaturii 
    Dănilă, Alina; Grosu, Iurie; Dănilă, Valeria; Bernic, Valentin; Gudumac, Eva (Academia de Ştiinţe a Moldovei, Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu", IMPS Institutul Mamei şi Copilului, 2025)
    Obiective: Să sintetizeze datele actuale privind variantele anatomice și malformațiile trunchiului celiac, cu accent pe implicațiile lor clinice în chirurgia hepatopancreatobiliară, transplant și radiologie intervențio ...
  • Prevalența și managementul hepatoblastomului la copil 
    Gudumac, Eva; Hotineanu, Adrian; Gîncu, Gheorghe; Bernic, Valentin; Burgoci, Sergiu; Gura, Nicolae; Samciuc, Oleg (Academia de Ştiinţe a Moldovei, Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu", IMPS Institutul Mamei şi Copilului, 2025)
    Hepatoblastomul reprezintă cea mai frecventă tumoră hepatică malignă la copil, cu o pondere de aproximativ 80% dintre neoplaziile hepatice pediatrice. Deși progresele în chimioterapie și chirurgie au îmbunătățit supraviețuirea ...
  • Renal complications of gout: a synthesis of current evidence 
    Cornea, Cornelia; Groppa, Liliana; Tagadiuc, Olga; Sasu, Boris; Rotaru, Larisa (CEP Medicina, 2026)
    Background. Gout, a chronic inflammatory disease caused by the deposition of urate, involves not only the joints but also the renal structures, generating complications with severe evolution. Renal damage associated with ...
  • Peripheral nerve compression in the lower limbs of athletes – clinical, diagnostic, and therapeutic aspects 
    Galușca, Vitalie; Hacina, Tamara (CEP Medicina, 2026)
    Background. Peripheral nerve compression is a common yet frequently overlooked cause of lower limb pain in athletes. Without timely diagnosis, it can delay return to sport. The underlying mechanisms include repetitive ...
  • Etiopathogenetic aspects of supraventricular tachycardia in young people 
    Musteață, Maria; Bugai, Rodica (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2026)
    Background. Supraventricular tachycardia (SVT) is the most common arrhythmia diagnosed in young people. The prevalence of SVT in young adults is about 2,29/1000 people, with a higher incidence in women vs men. Studying ...
  • Hypertrophic cardiomyopathy with left ventricular outflow tract obstruction. Clinical case presentation 
    Ostap, Felicia; Damaşcan, Alexandru; Ciobanu, Maria; Țurcan, Victor; Samohvalov, Elena; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Hypertrophic cardiomyopathy (HCM) is caused by genetic defects in sarcomeric proteins, with autosomal dominant inheritance. The estimated prevalence is 1:500 cases. It may remain undiagnosed for a long time, ...
  • Anomalie congenitală rară a ambelor uretere asociată cu despicatura palatină (prezentare de caz clinic) 
    Bernic, Jana; Roller, Victor; Ceban, Emil; Dumbrăveanu, Ion; Galescu, Andrei; Revenco, Adrian; Ciuntu, Angela; Sagaidac, Irina; Țarcă, Elena; Mîndru, Elena; Poștaru, Cristina; Sandrosean, Argentina; Railean, Silvia; Costiuc, Ecaterina; Gudumac, Eva (Academia de Ştiinţe a Moldovei, Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu", IMPS Institutul Mamei şi Copilului, 2025)
    This paper discusses two aspects of renal malformation pathology. This is an old condition, diagnosed only when the child was 11 years old. The correct diagnosis, based on dynamic monitoring of the patient, clinically, 42 ...
  • Knowledge, attitudes and practices regarding antimicrobial resistance: a study among the general population from the Orhei constructed wetland 
    Țapu, Livia; Ferdohleb, Alina; Burduniuc, Olga; Spinei, Larisa (Asociaţia chirurgilor “Nicolae Anestiadi” din Republica Moldova, 2026)
    Rezumat. Obiective. Rezistența la antimicrobiene este o problemă majoră de sănătate, deoarece compromite eficacitatea tratamentelor și crește riscul de infecții severe. Identificarea lacunelor în cunoștințe și planificarea ...
  • The correlation between prolonged NSAID use and the incidence of acute digestive complications 
    Munteanu, Artur; Munteanu, Ecaterina; Sârbu, Oxana; Rezneac, Larisa; Istrati, Valeriu (CEP Medicina, 2026)
    Background. Long-term administration of nonsteroidal anti-inflammatory drugs (NSAIDs) is one of the most frequent medication-related causes of upper gastrointestinal pathology, with a significant impact on population ...
  • Sănătatea este o condiție primordială în dezvoltarea durabilă a societății 
    Condraticova, Liliana (Asociaţia chirurgilor “Nicolae Anestiadi” din Republica Moldova, 2026)
  • Graves’ orbitopathy: the importance of statin therapy 
    Tidvă, Adelina; Rizov, Cristina (CEP Medicina, 2026)
    Background. Graves’ orbitopathy is the most common extrathyroidal autoimmune disorder, predominantly caused by hyperthyroidism. Prevention and development of an individualized treatment plan involve the use of statins ...
  • Cardiac myxoma as a rare etiological substrate of stroke: a case report 
    Dornea, Diana; Covali, Anton; Rezneac, Larisa (CEP Medicina, 2026)
    Background. Stroke is a serious neurological emergency with a high risk of long-term disability or death, especially in young patients with unclear or undetermined etiology. Benign cardiac tumors, such as right ventricular ...
  • Management of acute hyperkalemia in heart failure – a major challenge 
    Țurcan, Victor; Harghel, Inga; Samohvalov, Elena; Grăjdieru, Romeo; Saracuța, Ala; Grib, Livi (CEP Medicina, 2026)
    Background. Hyperkalemia is an entity with high prevalence in patients with heart failure (HF). Elevated potassium levels in HF represent both a direct risk of cardiovascular complications and an indirect biomarker of ...
  • Acute miocardial infarction in a patient with diabetes mellitus, clinical case 
    Anghelcev, Avenir; Avramova, Tatiana; Grib, Livi; Samohvalov, Elena; Grinevich, Pavel; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Diabetes mellitus (DM) is a major cardiovascular risk factor associated with an increased incidence of acute ischemic events, including acute myocardial infarction (AMI). Chronic hyperglycemia contributes to ...
  • The importance of early diagnosis and adequate treatment of anemia in the elderly 
    Dron, Dorina; Țerna, Eudochia (CEP Medicina, 2026)
    Background. Anemia affects a large part of the elderly population and represents a public health problem expected to increase in the coming years due to the aging population. Anemia in the elderly is perceived as a minor ...
  • Empirical antimicrobian treatment of the patient with infectious endocarditis. Clinical case 
    Turcu, Corina; Istrati, Alina; Samohvalov, Elena; Panfile, Elena; Găină, Valeria; Jacotă, Elena; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Infective endocarditis (IE) with negative blood cultures (BC) remains a severe pathology, with a high risk of mortality, caused by the progression of heart failure, embolic and neurological complications. ...
  • The impact of psychological stress and depression on functional gastrointestinal disorders in young people 
    Danoi, Ionela; Bugai, Rodica; Bugai, Rodica (CEP Medicina, 2026)
    Background. Functional gastrointestinal disorders affect up to 25% of young people. Psychological stress and depression, through complex mechanisms, due to the close interdependence between the gastrointestinal tract, ...
  • Non-Hodgkin's lymphomas of gastro-intestinal tract: actual diagnosis and treatment options 
    Capanji, Alina; Musteață, Vasile; Urescu, Dumitrița; Musteață, Larisa (CEP Medicina, 2026)
    Background. The gastrointestinal tract is the most common primary localization for extranodal non-Hodgkin's lymphomas, accounting for 20 to 40% of all extranodal malignant lymphomas. Approximately in 60-75% of cases, the ...