1. COLECȚIA INSTITUȚIONALĂ: Recent submissions

  • Liver transplantation for hepatocellular carcinoma 
    Hotineanu, Adriana; Burgoci, Sergiu (CEP Medicina, 2025)
    Introduction. Hepatocellular carcinoma is one of the most frequent complications of advanced liver cirrhosis, associated with high mortality. Liver transplantation is an effective therapeutic solution in selected cases, ...
  • Challenges in the use of glucocorticoids in transplantology 
    Guțu, Ina; Bacinschi, Nicolae; Țurcan, Lucia; Caracas, Anastasia; Mihalachi-Anghel, Maria (CEP Medicina, 2025)
    Introduction. Glucocorticoids (GCs) have long time played a key role in solid organ transplantation (SOT), thanks to their strong anti-inflammatory and immunosuppressive effects. However, their use presents a significant ...
  • The role of glycation on transplantology methods in cancer treatment 
    Grusac, Evgheni; Tagadiuc, Olga; Munteanu, Roman; Pantea, Valeriana; Sardari, Veronica (CEP Medicina, 2025)
    Background. Advanced glication end products (AGEs) are formed in result of Millard reaction in hiperglycemic conditions caused by Warburg`s effect. Many studies have shown the presence of AGEs in neoplastic tissues through ...
  • Regenerative approaches for managing percutaneous nephrostomy complications: stem cell and tissue engineering strategies 
    Goras, Valeria; Tanase, Adrian (CEP Medicina, 2025)
    Introduction: Percutaneous nephrostomy (PCN) is a crucial intervention for urinary tract decompression in obstructive uropathy, malignancy, and infection. However, it carries significant risks, including hemorrhage, ...
  • Material design in hard tissue engineering 
    Jian, Mariana; Codrea, Cosmin; Spoiala, Angela; Ficai, Denisa; Nacu, Viorel; Ficai, Anton (CEP Medicina, 2025)
    Introduction: Considering the high incidence and the relatively large amount needed, the overall market share of the bone grafting materials is ~49% of the total field of biomaterials and thus many researchers focused ...
  • Challenges in the treatment of ocular surface pathologies 
    Cușnir, Valeriu; Dumbraveanu, Lilia; Lupan, Valentina; Cociug, Andrian; Procopciuc, Vitalie; Cușnir, Valeriu V.; Balba, Rodica; Bostan, Mihaela; Nacu, Viorel (CEP Medicina, 2025)
    Introduction. Tissue transplantation at the ocular surface for therapeutic, tectonic, reconstructive, or optical purposes is a routine practice among ophthalmic surgeons worldwide. The main ocular surface pathologies ...
  • Nanocarriers that may bypass the blood-brain barrier 
    Croitoru, Dan; Todica, Vladislav; Andronachi, Victor; Andrusca, Alexandru; Visnevschi, Sergiu (CEP Medicina, 2025)
    Introduction: The blood-brain barrier (BBB), blood-cerebrospinal fluid barrier (BCSFB) and bloodbrain tumour barrier (BBTB) are regarded as potential barriers for drug delivery. Nanocarriers are designed in order to bypass ...
  • The prospects of selective JAK inhibitors in hematopoietic stem cells transplantation 
    Cozma, Octavian; Tonofa, Maria; Timercan, Tatiana (CEP Medicina, 2025)
    Introduction. Hematopoietic stem cell transplantation (HSCT) represents a life-saving therapy for hematological malignancies, but its efficacy is often compromised by graft-versus-host disease (GVHD). GVHD remains a major ...
  • Clinical case: the impact of renal transplantation in the patient with renal pathology and gout 
    Cornea, Cornelia; Ceban, Emil; Rotaru, Larisa; Groppa, Liliana; Sasu, Boris; Tagadiuc, Olga; Romanciuc, Grigore; Timbalari, Tatiana; Buga, Diana; Nacu, Viorel (CEP Medicina, 2025)
    Introduction:Renal transplantation is a radical treatment option for patients with chronic kidney disease (CKD), significantly impacting those with coexisting renal pathology, such as gout. The use of immunosuppressants ...
  • Cancer stem cells and tumor microenvironment: implications for therapy resistance and novel strategies 
    Colibaba, Vasile; Sardari, Veronica (CEP Medicina, 2025)
    Background. Cancer stem cells (CSCs) represent a distinct subpopulation of tumors, characterized by self-renewal capacity and multilineage differentiation potential. These cells interact dynamically with the tumor ...
  • The role of miR-152-5p in renal transplantation 
    Cojocaru, Madalina; Ambros, Ala (CEP Medicina, 2025)
    Introduction. miR-152-5p is a microRNA involved in the regulation of gene expression at the posttranscriptional level, primarily expressed in hematopoietic cells. It impacts the regulation of genes involved in T cells and ...
  • Fecal microbiota transplantation in cirrhosis: a microbiome-based therapeutic revolution 
    Marcu, Beatrice; Sardari, Veronica (CEP Medicina, 2025)
    Introduction. The gut microbiota, as well as the gut-liver axis, play a significantly important role in the fibrosis process. As fibrosis progresses to cirrhosis, it further worsens the microbiota, creating a vicious cycle ...
  • Q-SPECT CT in the assesment of post-pulmonary embolism complications: a new perspective on risk stratification and management 
    Ivanes, Igor; Sorici, Galina; Cîvîrjîc, Irina; Diaconu, Nadejda; Grosu, Aurel; Gorohova, Marina; Ivanes, Anastasia; Plugaru, Ana; Ambroci, Rada; Cărăuș, Victoria; Lupu, Diana; Rusanovschi-Balica, Olga; Surev, Artiom (CEP Medicina, 2025)
    Introduction. Pulmonary embolism (PE) is a severe cardiovascular condition associated with significant morbidity, often resulting in long-term complications despite adequate anticoagulation. Chronic thromboembolic pulmonary ...
  • The role of glycation processes in aging 
    Ghinda, Daniela; Sardari, Veronica (CEP Medicina, 2025)
    Background. Glycation is a non-enzymatic reaction in which reducing sugars react with free amino groups in proteins, lipids, or nucleic acids, leading to the formation of advanced glycation end products (AGEs). AGE ...
  • Review of literature on combined liver elastography techniques 
    Calistru, Natalia; Țarălungă, Tatiana; Harti, Aliona (CEP Medicina, 2025)
    Background. Liver elastography has become a pivotal non-invasive method for assessing liver fibrosis, offering an alternative to traditional biopsy. Techniques such as transient elastography (TE), point shear wave ...
  • Peculiarities of the molecular markers expression on peripheral blood lymphocytes in complicated relapse of recurrent idiopathic anterior uveitis 
    Khramenko, N.I.; Velychko, L.M.; Konovalova, N.V.; Bogdanova, O.V. (CEP Medicina, 2024)
    Uveitis is one of the most common ophthalmic diseases with many phenotype and clinical manifestations, involves a complex of immune-related cells interactions, including neutrophils and lymphocytes. It is important to ...
  • Emerging treatment possibilities in noninfectious ocular inflammation: what's on the horizon? 
    Vidovic Valentincic, Natasa (CEP Medicina, 2024)
    Noninfectious ocular inflammation, particularly uveitis, continues to be a leading cause of visual impairment and blindness globally. Traditionally, the management of these conditions has depended on corticosteroids and ...
  • Lienal vein – hemodynamic aspects in portal insufficiency 
    Cobîleanschii, Eugeniu; Cobîleanscaia, Liubov (CEP Medicina, 2025)
    Introduction. The length of the lienal vein is 8–12 cm; caliber 6–12 mm, rectilinear trajectory. The lienal vein traverses the border of the pancreatic body, then joins the superior mesenteric vein at the pancreas neck ...
  • The capacity of hepatic henodynamics in the nutritional assurance of hepatocytes in the elderly 
    Cobîleanschii, Eugeniu; Cobîleanscaia, Liubov (CEP Medicina, 2025)
    Introduction. Blood supply to hepatocytes is severely compromised as a result of the difficult exchange of substances between hepatocytes and plasma, by the continuous deposition of collagen in the space of Disse, ...
  • Hemodynamic indicators in the superior mesenteric vein in patients with hepatic cirrhosis 
    Cobîleanschii, Eugeniu; Cobîleanscaia, Liubov (CEP Medicina, 2025)
    Introduction. Blood from the small intestine drains through the superior mesenteric vein. Defective blood flow, caused by hemodynamic deviations, lead to intestinal ischemia. Under these conditions, the cells of the ...

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