1. COLECȚIA INSTITUȚIONALĂ: Recent submissions

  • Left ventricular free wall rupture - the most severe complication of acute myocardial infarction 
    Nadejda, Albu; Tcaciuc, Angela; Carauș, Victoria; Damascan, Alexandru; Grib, Andrei (CEP Medicina, 2026)
    Introduction. Left ventricular free wall rupture is a mechanical complication that can occur on the 5th-14th day post-AMI with an incidence of 2-4% and a mortality of 20%. The most common rupture is the posterior ...
  • Empirical antimicrobian treatment of the patient with infectious endocarditis. Clinical case 
    Turcu, Corina; Istrati, Alina; Samohvalov, Elena; Panfile, Elena; Gaina, Valeria; Simon, Ana; Grejdieru, Alexandra (CEP Medicina, 2026)
    Background. Infective endocarditis (IE) with negative blood cultures (BC) remains a severe pathology, with a high risk of mortality, caused by the progression of heart failure, embolic and neurological complications. ...
  • Echocardiographic features in diagnosing aortic stenosis 
    Stratu, Andreea; Samohvalov, Elena; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Aortic stenosis (AS) is a valvular condition that obstructs left ventricular outflow, commonly seen in the elderly and associated with increased morbidity and mortality. Echocardiography remains the standard ...
  • Infective endocarditis complicated by septic nephritis. Clinical case 
    Spatari, Xenia; Jacotă, Elena; Samohvalov, Elena; Spatari, Anastasia; Preguza, Victoria; Istrati, Alina; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) is a severe microbial disease that often occurs on the Background. of comorbidities and progresses with multi-organ complications, negatively impacting the disease prognosis. The ...
  • Infective endocarditis in a pacient with diabetes mellitus. Clinical case 
    Preguza, Victoria; Grăjdieru, Romeo; Samohvalov, Elena; Istrati, Alina; Spatari, Xenia; Jacotă, Elena; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) frequently develops in an immunocompromised patients with multiple comorbidities: diabetes mellitus (DM) (17–30%), hepatitis, liver cirrhosis, renal diseases, cancer, or AIDS. ...
  • Infective endocarditis with embolic syndrome. Clinical case 
    Istrati, Alina; Spatari, Xenia; Grib, Livi; Samohvalov, Elena; Jacotă, Elena; Gaina, Valeria; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) presents with systemic embolic complications in 10-57% of cases: cerebral (26.3%), splenic (6.8%), and pulmonary (6.1-32%), leading to a malignant course with disabilities (172,359 ...
  • Infective endocarditis with neurological complications. Clinical case 
    Gaina, Valeria; Jacotă, Elena; Samohvalov, Elena; Panfile, Elena; Turcu, Corina; Feodorovici, Evelina; Grejdieru, Alexandra (CEP Medicina, 2026)
    Introduction. Infective endocarditis (IE) is a serious infectious disease, with polyorganic complications, which causes a high risk of death (20-25%). In 20-40% of cases, IE is complicated by neurological disorders as: ...
  • Vascular damage in patients with diabetes mellitus and smoking 
    Dina, More; Angela, Tcaciuc; Tatiana, More (CEP Medicina, 2026)
    Background. Atherosclerosis is a progressive systemic disease associated with fatal cardiovascular (CV) complications. Diabetes mellitus (DM) and smoking are two major CV risk factors contributing to the onset of ...
  • The role of personalized medicine in redefining the clinical management of chronic obstructive pulmonary diseases (COPD) 
    Popovici, Daniela Georgeta; Lixandru-Dohotariu, Sorana; Lavinia, Carmen; Panait, Silvia; Scîntee, Gabriela; Vlădescu, Cristian; Ciutan, Marius (CEP Medicina, 2026)
    Background. For decades COPD has been managed uniformly based on pulmonary function parameters. Personalized medicine takes into account relevant phenotypes, endotypes, biomarkers, advanced imaging and comorbidities into ...
  • Glucose is not always the answer: a case of Auto-Brewery Syndrome 
    Țânț, Andrada; Reuț, Anca; Puriș, Cătălina-Maria; Țichindeleanu, Andra; Iancu, Bianca (CEP Medicina, 2026)
    Background. Auto-Brewery Syndrome (ABS) is a rare metabolic disorder characterized by the endogenous production of ethanol through the fermentation of ingested carbohydrates in the gastrointestinal tract, causing ...
  • Stigmatization in medicine: impact on patients, healthcare providers, and ethical standards of care 
    Anisei-Cojocaru, I.; Rogozea, L. (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    Stigmatization is a social phenomenon that adversely affects not only access to care but also the quality of medical services. Stigma occurs when patients – or even healthcare professionals – are treated differently, ...
  • Innovations in the treatment of severe and complex mental disorders 
    Coșciug, Ion V.; Deliv, Inga D. (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    The target group of patients of Community Mental Health Centers are patients with Severe Mental Disorders, such as schizophrenia, bipolar affective disorder, major depressive disorder, patients with dual diagnosis. ...
  • Historia vitae magistra est: the past and future of psychiatry in Bulgaria 
    Nakov, V.V.; Dimitrova, I.D. (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    Psychiatry in Bulgaria has evolved through a complex interplay of historical, social, and political forces. Understanding its development offers crucial lessons for improving contemporary mental health services and anticipating ...
  • Modulation of neurotransmitters and reconfiguration of brain circuits in treatment-resistant depression 
    Chihai, Jana (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    Treatment-resistant depression (TRD) represents a major public health challenge, affecting nearly one-third of patients with depressive disorders. Persistent neurobiological dysregulation of serotonergic, dopaminergic, ...
  • Actualities in addiction medicine training program 
    Alexinschi, O.E. (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    The complementary study program for the Addiction Medicine certificate offers a comprehensive, interdisciplinary approach, blending both educational content and practical skills needed to provide medical care for patients ...
  • Peculiarities of stigmatization of people with depression in adolescents 
    Suman, M.; Eșanu, A. (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    Depression is a complex mental disorder characterized by the lack of a positive affective background and a spectrum of associated emotional, cognitive, physical and behavioral problems. Understanding the causes and risk ...
  • Efficacy and mechanisms of dialectical behavior therapy (DBT) in borderline personality disorder: integrating evidence, clinical practice, and implementation 
    Adeola, Cornelia (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    Borderline Personality Disorder (BPD) and disorders of emotional dysregulation represent significant challenges in both diagnostic assessment and therapeutic management. DBT was developed to address these core features, ...
  • Artificial intelligence for early screening of depressive disorders in young adults 
    Rotarciuc, J.; Tureac, Irina; Nastas, Igor (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    Depressive disorders are highly prevalent among young adults but often remain undetected in early stages. Initial symptoms are usually subtle and overlooked, delaying access to care. Early recognition is crucial to reduce ...
  • Adolescent anxiety – a contemporary challenge for mental health 
    Cartaleanu, V.; Cebanu, A.; Nastas, Igor (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    Adolescence is a critical stage of development, marked by biological, cognitive, and social changes. Anxiety disorders affect approximately 31.9% of adolescents worldwide. The importance of understanding and addressing ...
  • Contemporary antipsychotic treatment in schizophrenia patients during pregnancy 
    Croitoru, V.; Oprea, Valentin (Universitatea de Stat de Medicină și Farmacie "Nicolae Testemiţanu" din Republica Moldova, Ministerul Sănătăţii al Republicii Moldova, 2025)
    Gestational schizophrenia reveals a major dilemma. Discontinuation of antipsychotic therapy exposes the patient to the risk of relapse, and maintenance of treatment involves possible adverse effects. Management requires ...

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