Abstract:
Introduction. In the modern world, there are high placebo response rates in various diseases, in
particular in the field of psychiatry. Accordingly, there is an increasing demand from medical
professionals for the development of new expert recommendations on the scientifically sound and
ethical use of placebos in clinical practice.
Aim of study. a comparative study of the placebo effect in the treatment of mental disorders.
Methods and materials. Information was collected and analyzed in the electronic databases
PubMed, Hinari, elsevier, e-library, cyberleninka. All sources over the past 10 years have been
analyzed.
Results. The magnitude of the placebo effect varies depending on the psychological susceptibility
of the participant and the type of mental disorder. There have been studies that have caused
considerable resonance in the field of science, since the placebo effect was so pronounced that it
formed the opinion that it should be used independently in the treatment of depressed patients with
mild to moderate depression. In some studies, the response rate to placebo was almost as high as
to antidepressants administration.
Conclusion. In a comparative analysis of the placebo effect in schizophrenia, BPD and BDR, we
conclude that the use of the placebo effect is more appropriate for mood disorders than for
schizophrenia. Despite the fact that the placebo effect remains an intriguing and widely studied
topic, it requires more detailed consideration in the field of mental disorders in order to modernize
treatment methods.
