The Materials of the National Scientific Conference with International Participation „Cells and tissues transplantation. Actualities and perspectives. The 3rd edition” dedicated to the 80th anniversary of the founding of Nicolae Testemitanu State University of Medicine and Pharmacy. Chisinau, March 21-22, 2025: [Abstracts]: Recent submissions

Now showing items 21-40 of 95

Liver transplantation from a brain-dead donor

Cheptea, Mihail; Hotineanu, Adrian (CEP Medicina, 2025)

Introduction: Liver transplantation from a brain-dead donor is a vital procedure, often the only solution for patients with terminal liver diseases. Evaluating its outcomes will involve analyzing demographic data, ...
Therapeutic drug monitoring of tacrolimus in renal transplant recipients

Caracaș, Anastasia; Guțu, Ina; Latus, Svetlana; Spînosu, Galina; Bacinschi, Nicolae (CEP Medicina, 2025)

Introduction. Tacrolimus, the calcineurin inhibitor has been the cornerstone of immunosuppression following renal transplantation for the last 10–15 years. The narrow therapeutic index and large pharmacokinetic interindividual ...
Urinary tract infections treatment in kidney transplant recipients

Caracaș, Anastasia; Babcinețchi, Victoria; Vasilache, Eugenia; Coreţchi, Ianoş; Bacinschi, Nicolae (CEP Medicina, 2025)

Introduction. Kidney transplantation remains the treatment of choice for patients with end-stage renal disease. Urinary tract infection in kidney transplant recipients is the most frequent and considered a potential cause ...
Isolation of mesenchymal stem cells from Wharton’s jelly

Caproş, Hristiana; Dondiuc, Iurie; Surguci, Mihai; Bologan, Ion; Potacevschi, Oleg (CEP Medicina, 2025)

Introduction: Mesenchymal stem cells (MSCs) derived from Wharton’s jelly of the umbilical cord are increasingly recognized for their potential in regenerative medicine. These cells offer significant advantages, including ...
Regenerative approaches for epidermolysis bullosa: tissue engineering and gene therapy

Bulicanu, Adelia; Cemortan, Igor (CEP Medicina, 2025)

Introduction: Epidermolysis bullosa (EB) is a group of rare genetic disorders characterized by skin fragility and blister formation. The current management of EB is mainly symptomatic, with no definitive cure. Recent ...
The effect of stimulating local immunity with autologous cells in the treatment of tissue inflammatory process on the body’s resistance to infection

Danilov, Lucian; Maniuc, Mihail; David, Valeriu; Ababii, Polina; Bugan, Maria; Furculița Daniel; Nacu, Viorel (CEP Medicina, 2025)

Introduction. The application of autologous mononuclear cells to the area of inflammatory affected tissue produces the stimulation of certain cytokines with anti-inflammatory properties, the proliferation of cells involved ...
Human tissue donation and transplantation in the Republic of Moldova

Buga, Diana; Țîmbalari, Tatiana; Romanciuc, Grigore; Ciubotaru, Ludmila; Visterniceanu, Dorian; Cornea, Cornelia; Fărîma, Marc; Ungureanu, Alina; Nacu, Viorel (CEP "Medicina", 2025)

Introduction: In recent years, human tissue transplantation has gained increasing importance in modern medicine, expanding both in scope and medical applications. Advances in surgical techniques, improvements in tissue ...
Renal transplant to a patient with type 2 cardiorenal syndrome who is on hemodialysis: clinical and prognostic factors to think about

Purteanu, Lilia; Pîntea, Dumitrița; Grejdieru, Alexandra; Tonofa, Marina; Slonovschi, Tamara; Ciobanu, Gabriela; Matcovschi, Laur (CEP Medicina, 2025)

Introduction. Type 2 cardiorenal syndrome (CRS-2) is a complex pathological entity characterized by decompensated chronic heart failure, leading to progressive deterioration of renal function. For patients with CRS-2 who ...
Breast tissue engineering: innovations, methods, and future perspective

Popova, Daria; Iordăchescu, Rodica; Verega, Grigore; Jian, Mariana; Nacu, Viorel; Stoian, Alina (CEP Medicina, 2025)

Introduction.The incidence of breast cancer, based on L.Wilkinson et al. in 2020, has reached 2.26 million cases worldwide, with mastectomy remaining the primary surgical approach. The critical importance of breast ...
Amniotic membrane therapy: a step toward faster ulcer healing

Mihaluța, Viorica; Stoian, Alina; Iordăchescu, Rodica; Raischi, Ion; Verega, Grigore; Nacu, Viorel (CEP Medicina, 2025)

Introduction. Neuropathic foot ulcers are a major health issue, particularly in patients with diabetes or peripheral neuropathy, significantly impacting mobility and quality of life. These ulcers are often difficult to ...
Epidemiology of healthcare-associated infections in children undergoing hematopoietic stem cell transplantation

Marga, Irina (CEP Medicina, 2025)

Introduction. Approximately half a century ago, allogeneic hematopoietic stem cell transplantation (HSCT) became an essential therapeutic option for treating severe conditions, thus offering a new chance at life for ...
Regenerative medicine in liver diseases and cellular mechanism of liver regeneration and cell-based therapies

Marcu, Beatrice; Sardari, Veronica (CEP Medicina, 2025)

Background. Liver transplantation remains the gold standard for end-stage liver diseases, but donor shortages necessitate regenerative alternatives. Induced pluripotent stem cells (iPSCs), liver progenitor cells (LSPCs), ...
Evaluation of the regenerative efficacy of biological dressings developed through tissue engineering

Macagonova, Olga; Cociug, Adrian; Țarălungă, Tatiana; Braniște, Tudor; Vereștiuc, Liliana; Nacu, Viorel (CEP Medicina, 2025)

Introduction. Recent advances in tissue engineering and regenerative medicine have developed innovative methods in skin regeneration, in the case of cutaneous wounds, where standard approaches are limited. The aim of the ...
Autotransplantation of the thyroid gland

Cojocaru, Cristina; Bour, Alin (CEP Medicina, 2025)

Introduction: Thyroid autotransplantation, where thyroid tissue is relocated within the same individual, is utilized in both human and animal models to preserve thyroid function following thyroidectomy, which aims to ...
Mimicking the host: gene addition via adeno-associated virus (AAV) to reduce rejection in organ transplants

Leanca, Iosif; Capcelea, Svetlana (CEP Medicina, 2025)

Background.Organ transplantation is a crucial medical advancement, offering life-saving treatment for patients with end-stage organ failure. Despite significant progress, graft rejection remains a major cause of transplant ...
The role of mesenchymal stem cell-derived extracellular vesicles in cardiac repair

Bogdanov, Alan; Badalyan, Albert; Babuci, Angela (CEP Medicina, 2025)

Introduction: Cardiovascular diseases remain the predominant cause of global morbidity and mortality. Traditional treatments, including therapeutical and surgical approaches, primarily address symptoms rather than ...
Addressing artificial intelligence gaps in transplant medecine: a machine learning solution

Scevenels, Laura; Bogdanov, Alan; Topor, Boris (CEP Medicina, 2025)

Introduction: Artificial intelligence (AI) shows promise in transplant medicine, particularly in organ matching and rejection prediction. However, gaps remain in personalized immunosuppression, including optimal drug ...
Trends in the development of tissue grafts for biomedical applications

Jian, Mariana; Nacu, Ana-Maria; Mostovei, Andrei; Cobzac, Vitalie; Motelica, Ludmila; Oprea, Ovidiu Cristian; Pantea, Valeriana; Corețchi, Ianoș; Ficai, Denisa; Ficai, Anton; Nacu, Viorel (CEP Medicina, 2025)

Introduction. Bone defects can occur as a result of trauma, infection, tumor, or extensive surgery. Graft-assisted bone regeneration is an evolving field, with trends aimed at optimizing biocompatibility, accelerating ...
Bacterial resistance in urinary tract infections in kidney transplant patients: literature review

Bacinschi, Nicolae; Dabija, Maria; Mihalachi-Anghel, Maria; Spinosu, Galina (CEP Medicina, 2025)

Introduction. Urinary tract infections are the most common complication in renal transplant patients and a major cause of morbidity, hospitalization and mortality. The incidence of urinary tract infections varies widely ...
Antimicrobial resistance of uropathogens after kidney transplantation

Babcinețchi, Victoria; Caracaș, Anastasia; Guţu, Ina; Bacinschi, Nicolae (CEP Medicina, 2025)

Introduction. Antibiotic resistance, particularly among gram-negative pathogens, has become a growing challenge in clinical practice. In kidney transplant recipients, the management of infections is particularly complex ...

Now showing items 21-40 of 95

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